Preparation of oral local applied paster and application thereof
A topical and oral technology, applied in the field of propolis preparations in medicine, can solve the problems of difficulty in exerting a therapeutic effect, unreasonable administration carriers, and inconvenient medication for patients, so as to improve medication compliance, reduce adverse reactions, and reduce medication times. Effect
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Embodiment 1
[0047] Embodiment 1, the preparation 1 of propolis solid dispersion
[0048] Take 100g of propolis extract dry powder, 50g of soybean lecithin, add 500ml of ethanol, heat under reflux until all samples are dissolved, filter, take the filtrate, and spray dry to obtain propolis solid dispersion.
Embodiment 2
[0049] Embodiment 2, propolis solid dispersion preparation 2
[0050] Propolis extract 20g, PEG 6000 50g, take the carrier material and heat to melt, add propolis extract, stir quickly, mix evenly, place at -20°C for rapid cooling, stand, take out and pulverize to obtain.
Embodiment 3
[0051] Embodiment 3, propolis solid dispersion preparation 3
[0052]Take 10g of propolis extract, 5g of polyvinylpyrrolidone, 0.5g of SDS, add 100ml of ethanol, heat until completely dissolved, and evaporate the solvent under reduced pressure to obtain the product.
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