Main ingredient of anemone rhizome, preparation process and application thereof

An extract and the technology of Diwu, applied in the main components, preparation and application fields of Diwu extract, can solve the problems of no specific treatment method and incompletely clear pathogenesis

Inactive Publication Date: 2006-02-22
湖北中医学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Because its pathogenesis is not completely...

Method used

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  • Main ingredient of anemone rhizome, preparation process and application thereof
  • Main ingredient of anemone rhizome, preparation process and application thereof
  • Main ingredient of anemone rhizome, preparation process and application thereof

Examples

Experimental program
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Embodiment 1

[0021] according to figure 1 The technical process is to extract the extract mainly composed of total saponins from the medicinal material of Radix Rhizoma Radix.

[0022] Take Radix Rhizoma Radix, add 2 to 8 times the mass of water and decoct 3 to 5 times, each time for 1 to 4 hours, filter, combine the filtrate, concentrate the filtrate into a liquid with a relative density of 1.04 to 1.1 at 60°C, let it cool, Add ethanol to make the alcohol content 40-80%, stir well, let it stand for 12 hours, filter, recover ethanol, volatilize until no alcohol smell, get extract, dissolve with water, clarify, and open non-polar or weak polar macropores Adsorption resin column, washed with water, discarded, and then eluted with 50-80% ethanol, collected eluate, recovered ethanol, concentrated, and vacuumed at 660-860mmH 2 O and drying at 60-100° C. for 12 hours, crushing, and passing through a 60-mesh sieve to obtain a Diwu extract with a mass content of 60%.

[0023] The resulting Diwu ...

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Abstract

The invention provides a Diwu extract with a mass content of 60%, which mainly comprises Diwu saponins, the four monomers are, 3-O-beta-D-pyran glucuronic acid-oleanolic acid-28-O-alpha-L-pyran rhamnose(1-4)-beta-D-glucopyranose(1-6)-beta-D-glycopyraniside, 3-O-beta-D-glucopyranose aldehyde acid-oleanolic acid-28-O-beta-D-glucopyranose(1-6)-beta-D-glucopyranoside, 3-O-alpha-L-pyran rhamnose(1-2)-beta-D-glucopyranose-oleanolic acid-28-O-alpha-L-pyran rhamnose(1-4)-beta-D-glucopyranose(1-6)-beta-D-glycopyraniside, 3-O-alpha-L-pyran rhamnose(1-2)-alpha-L-Arabinopyranosyl-oleanolic acid-28-O-alpha-L-pyran rhamnose(1-4)-beta-D-glucopyranose(1-6)-beta-D-glycopyraniside. The invention also discloses the process for preparing the abstract.

Description

technical field [0001] The present invention relates to an extraction process of a raw material drug, the structure of the main components of the raw material drug and the application of the raw material drug, specifically obtaining the Diwu extract from Diwu and the preparation process, and the structure of the four main monomer components in the Diwu extract , using Diwu extract as a raw material to make a traditional Chinese medicine preparation for the treatment of rheumatoid arthritis. Background technique [0002] Rheumatoid arthritis is the most common rheumatic disease and can affect multiple organs and tissues. Clinical morbidity is high. Because its pathogenesis is not completely clear, there is no specific treatment at present. [0003] The dried rhizome of Anemone flaccida Fr. Schmidt, a plant of the genus Anemone (Anemone flaccida Fr. Schmidt) in the Ranunculaceae family. It is recorded in "Guizhou Folk Medicine" and "Zhejiang Tianmu Mountain Drug Chronicle" ...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K31/704A61P29/00A61P19/02C07J63/00
Inventor 邴飞虹江俊
Owner 湖北中医学院
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