Peppermint oil dripping pills and its prepn. method

Abstract

A dripping pill of mint oil for treating chronic lithocholeoystitis, chronic cholecystitis, cholelithiasis, etc is prepared from mint oil, polyethandiol 2000-20000, beta-cycoldextrin and carboxymethyl starch sodium.

Description

technical field [0001] The invention relates to a medicine for treating diseases such as chronic calculous cholecystitis, chronic cholecystitis, gallstone hepatobiliary stagnation, damp-heat stomach stagnation, etc., and particularly relates to an oral preparation of a pharmaceutical composition with mint oil as the active ingredient. Background technique [0002] In our country, gallbladder stone has become a common and frequently-occurring disease, which has aroused widespread concern. According to statistics, gallbladder stones accounted for 52.8% of the national gallstone disease in the 1980s, and rose to 79.9% in the 1990s. Gallbladder stones have become a common disease and frequently-occurring disease, which has troubled thousands of households (Wang Bingsheng. The treatment of gallbladder stones should be standardized. Chinese Journal of General Surgery, Volume 15, Issue 10, October 2000). Gallstones and chronic cholecystitis often coexist, and the two can often be ...

AI Technical Summary

Problems solved by technology

However, due to preparation technology and other reasons, most oral preparations of drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the efficacy of the drug. It also directly affects the therapeutic effect

In addition, conventional dosage forms such as capsules will generate large dust pollution during the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment.

[0007] Chinese Invention Patent No. 200410080513.4 discloses a peppermint oil dripping pill, which has significantly improved the above-mentioned defects in conventional oral preparations. Among them, its physical characteristics have a great impact on product quality. First, when the product is stored for a period of time, its volatile components will reduce the drug content due to natural volatilization, which will affect the accuracy of patients' medication and reduce the therapeutic effect; secondly, because of It exists in liquid form, so it makes the condensation and solidification time long, the shape is not very good, and it is easy to deform when the ambient temperature is high, which seriously affects the product qualification rate in industrial production and indirectly increases the production cost.