50results about How to "Improve the effect of medication" patented technology

The present invention provides an apparatus and a method for a medication management. More particularly, the present invention relates to an apparatus and a method for managing a user's medication by providing an image of medicine prescribed to be taken at a medication time by using prescription information.

The present disclosure relates to an exendin-4 analogue PEGylated with polyethylene glycol or a derivative thereof, a preparation method, and a pharmaceutical composition for prevention or treatment of diabetes containing the same as an active ingredient. According to the present invention, the yield of an exendin-4 analogue can be increased via the selective PEGylation by using exendin-4 in which a cysteine is introduced into #40 site of the C-terminal, and treatment effect of medications can be increased, so that the exendin-4 analogue can be usefully applied as a composition for prevention or treatment of diseases caused by insulin hypersecretion.

A composition for making a deer antler wine is disclosed, which includes: a deer antler powder in an amount of 6-24 parts by weight; grapes in an amount of 15.5-62 parts by weight; tea in an amount of 4.5-18 parts by weight; and a ginseng in an amount of 6-24 parts by weight. A method for making a deer antler wine and a deer antler wine made thereby are also disclosed.

The present disclosure relates to an exendin-4 analogue PEGylated with polyethylene glycol or a derivative thereof, a preparation method, and a pharmaceutical composition for prevention or treatment of diabetes containing the same as an active ingredient. According to the present invention, the yield of an exendin-4 analogue can be increased via the selective PEGylation by using exendin-4 in which a cysteine is introduced into #40 site of the C-terminal, and treatment effect of medications can be increased, so that the exendin-analogue can be usefully applied as a composition for prevention or treatment of diseases caused by insulin hypersecretion.

The invention relates to a method for manufacturing medicament application identification. The medicament application identification comprises a braille capable of providing medicament application information and a typography graph capable of providing medicament application information. The method comprises the following steps: (a) designing the braille and the typography graph, photographing the braille and the typography graph and drawing a black draft; (b) manufacturing a printing plate by using the black draft, a negative plate with thickness of 35 microns and a screen printing plate through a direct / indirect method which uses the drying temperature of 150 DEG C; (c) adding printing ink into the printing plate to print a printed object, wherein the printing ink contains aqueous foaming agent and aqueous red dye in a ratio of 1 to 1; and (d) drying the printed object at the temperature of between 30 and 50 DEG C, and foaming the printed object for 2 to 10 seconds at the temperature of between 115 and 125 DEG C to obtain the printed object printed with the braille or the graph with the thickness of 0.2 to 2 millimeters. The method of the invention can manufacture the medicament application identification enabling visual impairment people, illiterates and seniors to accurately learn the medicament application information by touching or looking at the graph.

The invention discloses a pharmaceutical preparation for bleeding, pain and edema, comprising ice and Chinese herbal medicines treating bleeding, pain and edema; wherein, the portion of the ice is 4000; the Chinese herbal medicines treating bleeding, pain and edema are composed of raw medicine with the following weight portion: 1-5000 portion of notoginseng, 1-5000 portion of bletilla, 1-5000 portion of galla chinensis, 1-5000 portion of asiatic moonseed, 1-1000 portion of borneol, 1-2000 portion of pearl powder. The pharmaceutical preparation has the advantages: the pharmaceutical preparation plays three roles of physical function of the ice, drug effect of the Chinese herbal medicines (notoginseng, asiatic moonseed), and direct effect on administration place; the pharmaceutical preparation has good therapeutic effect to stop bleeding, relieve pain or take away the pain, relieve edema, and prevent infection after oral or laryngeal surgery.

The invention discloses a solid or liquid pesticide composition of cyclodextrin and a dipyridyl herbicide clathrate compound. The solid or liquid pesticide composition comprises dipyridyl herbicide and cyclodextrin according to the mass ratio of 1: (0.5-1:9). The invention also discloses a preparation method of the solid or liquid pesticide composition of the cyclodextrin and the dipyridyl herbicide clathrate compound. The method comprises the following steps: mixing 9 parts by mass of cyclodextrin and 9-63 parts by mass of water; adding 1-18 parts by mass of dipyridyl herbicide to fully mix; heating to 60-80 DEG C in a dark condition and stirring, so that the system is completely or evenly dissolved; carrying out heat preservation for an hour; preparing the liquid pesticide composition from the system which is completely dissolved into a solution; and preparing the powdery solid pesticide composition from the evenly dissolved system. The pesticide composition disclosed by the invention can be in a solid state or a liquid state; the dipyridyl herbicide clathrate compound is strong in activity, stable in property, and long in quality guarantee period; the thrill is lower than that of a common water reducing agent; a contact damage of people and livestock is reduced; the pesticide composition is not easily diffused to pollute the environment.

The invention provides a systematic pesticide for the whole course of an apple plantation period. The pesticide comprises twelve components such as benziothiazolinone. The invention also provides an apple plantation period whole course systematic protection method. The method provides a systematic and globalized solution scheme, ensures scientific pesticide application through orchard workers, is convenient for scientific pesticide application and prevents pesticide abuse. Through prevention and promotion of health growth of a fruit tree, the method realizes less pesticide use and improves pesticide effects. All components of the pesticide can respectively produce effects and organically cooperate with each other according to a pesticide use stage order so that prevention and control effects are improved and fruit tree growth is promoted.

A dripping pill of mint oil for treating chronic lithocholeoystitis, chronic cholecystitis, cholelithiasis, etc is prepared from mint oil, polyethandiol 2000-20000, beta-cycoldextrin and carboxymethyl starch sodium.

The present invention pertains to the art of skin itching resistance. The present invention is characterized in that firstly anti-itching liquid is dripped on the itching skin surface; then cupping, or bell pumping, or suction bulb is used to produce negative pressure above the itching skin so as to make the skin rapidly bumped and promote the liquid to penetrate the skin, thus achieving the aim of rapidly resisting the itching. The anti-itching liquid of the present invention is obtained as follows: a mixture of one or more than one of lightyellow sophora root, manyleaf paris rhizome and violet is soaked in liquor or alcohol with corresponding concentration; then a soak solution is obtained through filtration and added with menthol. The present invention with simple production, low cost and less dosage has the functions of itching resistance and disinfection and greatly reduces the diseases spread by mosquitoes. The decompression method can greatly increase the curing effect of various anti-itching liquids and skin drugs in the market at present.

The present invention relates to a long-acting tretinoin intraocular slow-releasing system, including tretinoin and medicinal carrier, their weight ratio is 0.1:0.9-0.9:0.1, the medicinal carrier canbe synthetic biodegradable high-molecular material, natural biodegradable high-molecular material or their mixture. The medicine-releasing period of said invented long-acting tretinoin slow-releasingsystem is one week to one year. It has the important regulation action for proliferation and differentiation of cell, can influence differentiation and proliferation of tissue cell so as to can inhibit the growth of retinal pigment epithelial cell and fibroblast and production of PVR.

The inventeion discloses maca flower superfine powder and a preparation method thereof. The preparation method comprises the following steps: S1, drying, namely first pre-freezing maca flowers, and performing vacuum freeze drying, so that the moisture content is 3-7%; S2, coarse grinding, namely grinding the dried maca flowers into coarse powder, and standing under the condition of 0-15 DEG C; and S3, superfine grinding, namely introducing air subjected to freeze drying into the coarse powder, and obtaining the maca flower superfine powder by adopting a cell disruption superfine grinding technology, wherein the particle size of the powder is less than 10 microns. According to the invention, the defects that the traditional Chinese medicine health care products are complicated in processing, nutritive materials are lost in the processing process and the like are overcome due to the adoption of a low-temperature disruption superfine grinding method. Pigments, other additives and the like are not added in the operating process, so that the nutrition and flavor substances of the maca flower are remained to the greatest degree, the obtained maca flower superfine powder is pure, natural, safe and sanitary, the retention rate of active ingredients such as macamides, glucosinolate, adenosine, total saponins and the like is high, and the powder is uniform.

The invention discloses an umbilical region dropping liquid for eliminating dampness and reducing weight and a preparation method thereof, and belongs to the technical field of dampness-eliminating and weight-reducing herbal extracting solutions. The Umbilical region dropping liquid comprise the following components: pericarpium citri reticulatae, poria cocos, lotus leaves, semen cassiae and the like. The preparation method comprises the steps of raw material crushing, ethanol soaking, ethanol percolation, evaporation purification, ultrasonic activation, blending and further activation. At present, oral weight-reducing medicines in the market can damage bodies to different degrees, external medicines also have allergy phenomena, and the dampness-clearing weight-reducing umbilical region dropping liquid have no side effects, are quickly absorbed, have good fat-reducing effects and are particularly suitable for abdominal weight loss.

The invention discloses a preparation method and application of PAMs (natural plant antimicrobial solution) hydrogel patch. The hydrogel patch is prepared from 15-45 parts by weight of glycerol, 2-6 parts by weight of NP-700, 0.2-0.6 parts by weight of dihydroxyaluminium aminoacetate, 13.6-40.7 parts by weight of distilled water, 0.1-0.3 parts by weight of tartaric acid, 1.5-4.5 parts by weight ofazone, 1.5-4.5 parts by weight of propylene glycol, 0.25-0.75 parts by weight of SDS (sodium dodecyl sulfate), and 15.85-47.55 parts by weight of PAMs. The hydrogel patch provided by the invention has the beneficial effects of good moldability, viscoelasticity, gas permeability, good peeling property from skin and good therapeutic effect on skin burns, and can prevent skin ulceration, and has good antimicrobial and anti-inflammatory effects on wounds and good repairing effects on wound surface to slow down the problem of scar residue. The hydrogel patch is obtained by one-time heat preservation crosslinking, and the operation is convenient and advantageous for large-scale production.

The invention provides a green prevention and control method for diseases and insect pests in rice planting. The green prevention and control method comprises the following steps of soil selection andtreatment, specifically, selecting a dry field which is high in terrain, high in dryness, good in drainage and free of rice planting for many years, cleaning residual fallen leaves and weeds on the soil, deeply ploughing the soil by 30-40 cm for airing 20-25 days before sowing, and disinfecting the soil by 3-4 kg of potassium permanganate per mu; seed selection and treatment; mechanical plowing and rice seedling transplanting; and green prevention and control of the diseases and insect pests. By means of the green prevention and control method, according to the situation of the diseases and insect pests in the rice growth period, pesticides are scientifically applied, residues are few, the residual time is short, the use amount of the pesticides in the rice production process is reduced,and the occurrence of large-area diseases and insect pests of rice is effectively controlled and prevented.

The invention discloses a disposable urinary bladder perfusion apparatus and belongs to the field of medical devices. The disposable urinary bladder perfusion apparatus comprises a perfusion apparatusbody, wherein a main pipe cavity is formed in the perfusion apparatus body, a fixed balloon is arranged at the inserting end of the perfusion apparatus body and communicates with the main pipe cavity, and a plurality of injection micropores are uniformly distributed on the outer wall of the fixed balloon; a liquid medicine injection port is formed in the tail end of the main pipe cavity and connected with a three-way pipe, the three-way pipe comprises a first empty needle port and a second empty needle port which communicate with the main pipe cavity, a rotary switch is arranged at the intersection position of the two empty needle ports, and connection and disconnection of the two empty needle ports can be controlled by changing the angle of the rotary switch. By means of the injection micropores in the fixed balloon, a liquid chemotherapeutic drug can be dispersed in the urinary bladder, so that the liquid chemotherapeutic drug makes full contact with the inner wall of the urinary bladder, the medication effect is improved, and the staying time of a patient in a hospital is shortened; and by means of the design of the three-way pipe, the occupational exposure risk to a medical worker due to secondary puncture in the same position is reduced.

The invention provides medicinal liquor for treating rheumatic arthritis, hyperosteogeny and lumbar disc herniation, and a preparation method thereof. The medicinal liquor is prepared from the following raw materials in parts by weight: 43-47 parts of common threewingnut roots, 8-12 parts of raw kusnezoff monkshood roots, 8-12 parts of raw sichuan axonite roots, 7-11 parts of cassia twigs, 7-11 parts of Chinese angelica roots, 7-11 parts of achyranthes bidentata, 7-11 parts of pawpaw, 7-11 parts of safflower, 7-11 parts of notopterygium roots and 150-250 parts of white spirit. The preparationmethod comprises the following steps: a, decocting the common threewingnut roots, raw kusnezoff monkshood roots and raw sichuan axonite roots with big fire for 30-60 minutes; and b, adding other traditional Chinese medicines, and carrying out decoction twice; and c, mixing the decoction, carrying out concentrating, and then adding the white spirit, white spirit uniform mixing, and bottling. Compared with the prior art, the common threewingnut roots with are used for treating rheumatic stubborn arthralgia; meanwhile, a specific preparation method is applied, the toxicity of the medicinal materials is reduced, the medication effect is enhanced, the aim of curing severe rheumatism is achieved, and the cure rate reaches 95% or above.

The present invention relates to a mancozeb inclusion complex pesticide preparation. It is made up by including the mancozeb molecules with cyclodextrin with cyclic molecular structure. The describedcyclodextrin can be one of various cyclodextrins and its derivatives or mixture of them. Because several hydroxyl groups are distributed on the exterior of the cyclodextrin, it has good hydrophilic property, said cyclodextrin can be dissolved in water, so that the stability, water solubility and emulcification stability of the compound included by cyclodextrin can be raised, at the same time the release speed of the medicine included by said cyclodextrin can be delayed, and in the biological body said medicine can be quickly released.

The invention relates to an integrated disease and insect pet control method for rice. The control is carried out according to different growth periods of rice, and the method includes the following steps: 1) disease and insect pet control treatment for seeds before sowing; 2) disease and insect pet control treatment for a rice field before transplanting; and 3) disease and insect pet control treatment in the growth periods. The method carries out the disease and insect pet control management from three aspects of the soaked seeds, the rice planting field and the growth periods, mainly uses Chinese herbal medicine as a control agent instead of conventional pesticides for disease and inset pet control, and so the pesticide pollution is reduced and the agent application effect is improved. According to the method, a plurality of diseases and insect pests can be controlled, the chemical pesticide pollution can be reduced to the greatest extent, and the amount of pesticide residues in grain can be reduced, thereby guaranteeing the human health. Meanwhile, the method greatly reduces the production cost of grain crops, saves the labor, time and pesticide purchasing expense used by the disease and insect pet control during the grain production, and provides a novel way for the agricultural disease and insect pet control.

The invention discloses an auxiliary tray for replacing cesarean section incision auxiliary material. The auxiliary tray for replacing cesarean section incision auxiliary material comprises a base; the upper surface of the base is fixedly connected with a supporting column; the top end of the supporting column is fixedly connected with a containing box; a groove is formed in the top end of the supporting column; a rotating part is fixedly connected to the surface, close to the bottom end, of a rotating shaft; an impeller is fixedly connected to the surface, close to the top end, of the rotating shaft; a supporting tray is slidably connected to the inner wall of the containing box; the bottom end of a push rod is hinged to the inner wall of the containing box, and a material taking openingallowing an auxiliary material containing barrel to penetrate through is formed in the top of the containing box. Through cooperation of the above structures, the problems that an existing auxiliary tray is single in structure, common medical instruments are not easy to place while auxiliary material is placed, meanwhile, the auxiliary materials and the medical instruments are difficult to store in time after use, and inconvenience is brought to use are solved.

The invention belongs to the field of genetic engineering and tumor medicine, and discloses an SNP (single nucleotide polymorphism) marker relevant to prevention of colorectal cancer by the aid of non-steroidal anti-inflammatory medicines and application of the SNP marker. The SNP marker is a composition of rs12217975, rs1927466, rs7586006, rs17868336, rs1500482, rs16973225, rs10505806, rs6717546, rs2965667, rs73172231, rs16825767, rs1902023, rs2745559, rs73172243 and rs2920421. The SNP marker and the application have the advantages that the SNP marker can be used for guiding prevention and treatment clinical medication of the non-steroidal anti-inflammatory medicines for colorectal patients, accordingly, medicine abuse can be reduced, and excessive medical treatment can be prevented.

The invention discloses an extrudable glycerine enema container, which comprises a liquid medicine container bottle, a liquid medicine extrusion pipe and a liquid medicine extrusion pipe plug cover, wherein the bottom part of the liquid medicine extrusion pipe is inserted into the bottom part in the liquid medicine container bottle from a tubular opening in the upper part of the liquid medicine container bottle; the bottom opening of the liquid medicine extrusion pipe is a bevel angle; the liquid medicine extrusion pipe and the tubular opening in the upper part of the liquid medicine container bottle are fixedly connected with each other by a liquid medicine extrusion pipe sealing interface; the liquid medicine extrusion pipe plug cover is arranged in the upper opening of the liquid medicine extrusion pipe; and the liquid medicine container bottle is made of an elastic blow molding material. When the extrudable glycerine enema container is used, the opening in the upper end of the liquid medicine extrusion pipe is inserted into a human anus; and a liquid medicine bottle can be extruded for a plurality of times, so that a liquid medicine enters the opening in the upper end of the liquid medicine extrusion pipe to be extruded into the anus through the bottom part in the liquid medicine container bottle and the bottom opening of the liquid medicine extrusion pipe; and the liquid medicine can be completely extruded into the human anus through the liquid medicine container bottle. Therefore, the medication effect is greatly strengthened; and the extrudable glycerine enema container is economical, environmentally friendly, easy to process and manufacture, low in cost, convenient to use, healthy, comfortable and suitable for service conditions of various medication environments.

The invention belongs to the technical field of injection, and discloses a preparation and use method of an improved injection mixture. The improved injection mixture is composed of a transfected liposome vector, a foreign plasmid and an exogenous miRNAs solution in proportion. The preparation method comprises diluting the constructed foreign plasmid using the sterilized ddH2O to the concentrationof 500 ng / [mu]L; diluting the prepared miRNAs to the concentration of 20 pmol / [mu]L using the sterilized ddH2O; then preparing the transfected liposome vector; preparing 2-4[mu]L of mixed solution according to the proportion that the transfected liposome vector: Sox9a exogenous plasmid: exogenous miRNA (one or mixture of more) = 2:1:1 ratio. The use method includes adopting in vitro microinjection of gonadal glands combined with electrotransfection. The differentiation of the testis and the ovary of 6-month zebrafish and the gonad regeneration of the adult fish can be controlled by adding different proportions and different kinds of exogenous miRNAs to the original mixed solution.

The invention discloses an oral ulcer fixed-point nursing device, and relates to the technical field of medical nursing appliances. The device comprises a pair of magnets which attract each other. The outer wall of each magnet is sleeved with a protective sleeve. A connecting pad is adhered to the outer wall of the protective sleeve through an adhesive tape; absorbent cotton is arranged on the outer wall of the connecting pad. The device has the beneficial effects that the absorbent cotton is fed into the ulcer in the oral cavity after being dipped in the medicament and connected with the magnet, and is magnetically attracted by the magnet outside the oral cavity, so that the absorbent cotton is clamped at the ulcer to perform fixed-point medication treatment on the ulcer, the absorbent cotton prevents the medicament from being diffused to influence the drug effect, and the medication effect and the treatment effect are improved through fixed-point medication on the ulcer; the patient can close the oral cavity to prevent secreted saliva from flowing out, so that the use is more sanitary.

The invention belongs to the field of genetic engineering and tumor medicine, and discloses an SNP (single nucleotide polymorphism) marker relevant to prevention of colorectal cancer by the aid of non-steroidal anti-inflammatory medicines and application of the SNP marker. The SNP marker is a composition of rs12217975, rs1927466, rs7586006, rs17868336, rs1500482, rs16973225, rs10505806, rs6717546, rs2965667, rs73172231, rs16825767, rs1902023, rs2745559, rs73172243 and rs2920421. The SNP marker and the application have the advantages that the SNP marker can be used for guiding prevention and treatment clinical medication of the non-steroidal anti-inflammatory medicines for colorectal patients, accordingly, medicine abuse can be reduced, and excessive medical treatment can be prevented.

The inventeion discloses maca flower superfine powder and a preparation method thereof. The preparation method comprises the following steps: S1, drying, namely first pre-freezing maca flowers, and performing vacuum freeze drying, so that the moisture content is 3-7%; S2, coarse grinding, namely grinding the dried maca flowers into coarse powder, and standing under the condition of 0-15 DEG C; and S3, superfine grinding, namely introducing air subjected to freeze drying into the coarse powder, and obtaining the maca flower superfine powder by adopting a cell disruption superfine grinding technology, wherein the particle size of the powder is less than 10 microns. According to the invention, the defects that the traditional Chinese medicine health care products are complicated in processing, nutritive materials are lost in the processing process and the like are overcome due to the adoption of a low-temperature disruption superfine grinding method. Pigments, other additives and the like are not added in the operating process, so that the nutrition and flavor substances of the maca flower are remained to the greatest degree, the obtained maca flower superfine powder is pure, natural, safe and sanitary, the retention rate of active ingredients such as macamides, glucosinolate, adenosine, total saponins and the like is high, and the powder is uniform.

The invention discloses medical modified collagen matrix drug loading sponge. The sponge is prepared by carrying out modification treatment on a porous collagen matrix through a microorganism modifying agent, and finishing loading of a drug carrier by utilizing a polar group on the surface of the modified porous collagen matrix, wherein the microorganism modifying agent comprises falciform cellulose bacteria, acetobacter xylinum and saccharomycetes; the drug carrier is a drug which does not react with the porous collagen matrix and is hydrophilic. According to the medical modified collagen matrix drug loading sponge disclosed by the invention, the quantity of hydrophilic groups on the surface of the porous collagen matrix and the hydrophilic polarity are increased, so that the drug loadingdosage of the modified collagen matrix on hydrophilic drugs is increased; the finally prepared medical modified collagen matrix drug loading sponge has a great drug loading dosage, a remarkable medical effect and a lasting medical effect and can be widely applied to medical utilization of various departments.

The invention discloses a medical carrying sponge with chitosan modified porous gel matrix and a preparation method. A medical sponge load with chitosan modified porous gel matrix is prepare by modifying chitosan porous gel matrix with microbial modifier. And utilize polar groups on that surface of modified chitosan porous gel matrix to complete loading of drug carrier. The microbial modifier comprises lactobacillus, bifidobacterium and yeast; The drug carrier is a drug that does not react with the chitosan porous gel matrix and is hydrophilic. A surface of that chitosan porou gel matrix is biochemically modified to increase the numb of hydrophilic groups and the hydrophilic polarity of the surface of the chitosan porous gel matrix, thereby increasing the drug load of the chitosan porou gel matrix to hydrophilic drugs. The final prepared chitosan modified porous gel matrix drug-loaded medical sponge has the advantages of large drug loading amount, remarkable drug application effect, lasting drug effect, good biocompatibility and wide application.

The invention relates to a wound healing pressurizing device for pediatric surgery. The device comprises a connecting base, connectors are fixed to the two sides of the connecting base respectively, the connectors are used for fixing bandages, a circular through groove is formed in the inner side of the connecting base, a pressing assembly is inserted into the through groove, and the pressing assembly is connected with an adjusting assembly rotationally installed on the connecting base; a containing cavity is reserved between the adjusting assembly and the pressing assembly, and the inner sideof the containing cavity is used for containing a medicine bag; a one-way air outlet valve and a one-way air inlet valve are installed on the adjusting assembly, an air outlet pipe is arranged on theouter side of the one-way air outlet valve, and a flow control assembly used for adjusting the air circulation amount is arranged on the air outlet pipe. The containing cavity is used for containinga medicine bag, the air outlet pipe and the flow control assembly are arranged in a matched mode to achieve the air flowing speed of the inner side of the containing cavity, the standing time of a medicine in the containing cavity is controlled according to needs, and the medication effect is improved.