81 results about "Medication effects" patented technology

Computer modeling of interactions between and among cortico and subcortical areas of the human brain, for example in a normal and a pathological state resembling schizophrenia which pathological state has inputs representing the effects of a drug(s), for the purpose of using the outputs to predict the effect of drugs in psychiatric and cognitive diseases on one or more clinical scales. Diseases that can be modeled include psychiatric disorders, such as schizophrenia, bipolar disorder, major depression, ADHD, autism, obsessive-compulsive disorder, substance abuse and cognitive deficits therein and neurological disorders such as Alzheimer's disease, Mild Cognitive impairment, Parkinson's disease, stroke, vascular dementia, Huntington's disease, epilepsy and Down syndrome. The computer model preferably uses the biological state of interactions between and among cortico and subcortical areas of the human brain, to define the biological processes related to the biological state of the generic synapse model, the striatum, Locus Coeruleus, Dorsal raphe, hippocampus, amygdala and cortex, as well as certain mathematical relationships related to interactions among biological variables associated with the biological processes.

A diagnosis system and method comprising a handwriting data collection and analysis software and accompanying tools for diagnosing a given condition such as an illness, a mental illness, a physiological condition, a mental or emotional state, medication effect, a personality trait, a skill, an expertise, deception or truth writing. The handwriting of a control group known to have a condition is analyzed in order to determine the detectable characteristic indicators of that group. Such measured indicators comprise spatial, temporal and pressure measures for each writing stroke. The handwriting of a subject is then analyzed to determine if the measured indicators indicate statistically that the subject can be diagnosed with a condition.

The invention relates to the technical field of devices and methods for supervising the medicine taking of patients, and discloses a device for supervising the medication compliance of a patient and tracking medication effects and a using method of the device. The device for supervising the medication compliance of the patient and tracking the medication effects comprises a medicine box, an intelligent terminal device, a patient mobile phone and a cloud service platform, wherein the intelligent terminal device is fixedly arranged in the medicine box, and comprises a shell; a sensor capable of sensing the opening of the medicine box, a wireless communication module, a timed reminding module, a sensing module and a power module are arranged in the shell. According to the device for supervising the medication compliance of the patient and tracking the medication effects and the using method of the device, the patient can effectively execute a medication plan, and can be effectively supervised to take medicine, the medication effects of the patient can be effectively tracked, the medication compliance of the patient is improved, and an important basis is provided for the subsequent treatment of the patient.

The invention provides an oral solution containing ambroxol hydrochloride and salbutamol sulfate, and belongs to the technical field of medicines. An auxiliary material of the oral solution mainly comprises preservatives and corrigents. The oral solution is used for treating respiratory system diseases such as acute and chronic bronchitis, asthmatoid bronchitis and bronchial asthma, has a simple prescription, a good medication effect and a good taste, and is quick in response.

The invention discloses an injector reducing residual volume of liquid medicine. The injector comprises an injector cylinder, an injection piston. The injector cylinder is provided with a nipple. Theinjection piston is arranged in the injector cylinder. The injector is characterized in that a hole is in the injection piston, a residual medicine piston is arranged in the hole of the injection piston, and is cooperated with the hole in a sealed manner. When liquid medicine is extracted, the injection piston and the injector cylinder are cooperated to extract the liquid medicine. When the liquidmedicine is injected, a piston on the front part of the injection piston discharges medicine of the injector cylinder, and then the residual medicine piston is pushed, a sealing gasket is cooperatedwith the nipple, and the sealing gasket on the front end of a piston rod completely discharges medicine in the nipple. After completion, a spring retaining ring and a return spring are cooperated, andthe piston rod is returned, to complete to inject the medicine. The injector is simple in structure, convenient in operation, and is safe and reliable. The injector can completely discharge residuesin the nipple, medicine injection dose is more accurate, and medicine waste is eliminated, medication effect and curative effect are guaranteed, and cost of a patient is reduced.

The invention provides a target region enrichment sequencing method for 165 genes. According to the method, 165 group-entering genes are screened according to the cancer genome and medicine data of TCGA, NCCN, FDA and the like. The 165 genes comprise detection genes recommended by NCCN, target genes corresponding to target medicines and important clinical medicines approved by FDA, genes influencing the medication effect of the target medicines, and genes influencing the chemical drug sensibility and toxic and side effects. According to the method, the exon regions of the 165 genes are enriched at once through the probe capturing technology, the multi-gene and multi-target parallel depth high-throughput sequencing is realized, the various variation types (such as point mutation, deletion, insertion, fusion and copy number amplification) of the genes can be simultaneously detected, and the detection depth and accuracy are superior to those of the prior art.

The invention discloses a medicine composition for ischemic diseases, which comprises the following raw materials by weight portion: 5 to 15 portions of radix astragali, 2 to 8 portions of Salvia miltiorrhiza, 1 to 5 portions of ligusticum wallichii, 1 to 5 portions of safflower and 1 to 3 portions of earthworms. The invention simultaneously discloses application of the medicine composition in preparing pharmaceutical preparation for treating ischemic cerebrovascular disorder, application of the medicine composition in pharmaceutical preparation for treating ischemic cardiomyopathy, and application of the medicine composition in pharmaceutical preparation for treating ischemic enteropathy. The medicine composition can be used for preventing and treating ischemic diseases such as ischemic cerebrovascular disorder, ischemic cardiomyopathy and ischemic enteropathy, and can also be used for treating coronary heart disease, arteriosclerosis and mesenteric vein embolism. The medicine composition has strong pertinence and obvious medicine effect, and provides more application selections for clinical medication.

The invention discloses a monitoring device and a monitoring method for remote detection of human vital signs. The device comprises a main control unit, wherein the main control unit is connected to an electrocardiogram and heart rate information processing unit, a blood pressure and pulse information processing unit, a blood oxygen concentration and pulse rate information processing unit, a body temperature information acquisition unit, a respiratory information identifying unit, a Bluetooth / WIFI signal transmitting and receiving unit and a GPS positioning and 2G / 3G / 4G remote communication unit. The monitoring device provided by the invention has the advantages of being simple in structure, outstanding and sensitive in performances and long in service life, regardless of regional and spatial limitation, the human vital sign multi-parameter monitoring equipment, which is applicable to an inpatient department of a hospital, is placed on the body of a discharged patient as a wearable product, so that doctors can follow up postoperative or medication effects in real time; and meanwhile, in the case that vital sign parameters of a monitored object become worse rapidly, an illness state can be timely mastered or a warning (one-touch calling and positioning) can be transmitted timely, so that the monitored object can be rescued timely and effectively to the greatest extent.

The invention provides a method for measuring the concentration of free magnesium ions in red cells by fluorescent indicators through being combined with flow cytometry, and aims at precisely measuring the concentration level (RBC[Mg<2+>]i) of endogenous metallic ions of magnesium ions closely interrelated to great amount of life activities in the red cells in the free state. A magnesium ion fluorescent probe is used for combining the flow cytometry, and the method has the advantages that the measurement is fast and is in real time; the operation is simple and convenient; the sample collection flux is high; the measuring result is precise and stable, and the like. The RBC[Mg<2+>]i measured by the method provided by the invention can be used for effectively showing the magnesium loss of the animal body in the diet intake lack, diabetes and senility process, and can also be used for effectively showing the memory power level of old animals and predicting the medication effect of exogenous magnesium compensation treatment of old animal memory injury. The RBC[Mg<2+>]i measured by the method can be a potential clinic physical index, and the reference standard can be provided for the health diet structure conditioning, disease diagnosis and monitoring and individualized precise medical care medication.

The present invention discloses a medication compliance assessment method. The method comprises the steps of: recording actual medication time and the number of medication times of a patient; calculating and obtaining an actual medication completion rate W and an actual medication time accuracy rate Q through the actual values of the medication time and the number of medication times and a set value; setting weights [Alpha] and [Beta] for the influence of the medication compliance for the actual medication completion rate and the actual medication time accuracy rate; comprehensively calculating and obtaining a medication compliance index AI, wherein the closer to 100% the AI, the better the compliance, and the compliance is employed to pre-assess the medication effect and perform intervening for the patient medication. In a condition that the patient takes various medicines, the medication compliance index of each medicine can be subjected to further weighted average to obtain a comprehensive average medication compliance index. The method can accurately, timely and extensively reflect the patient's medicine taking condition and can fully consider the influences of different diseases and different medicine treatments on the calculation of the compliance so as to allow the indexes to more have actual meaning in the guidance of the clinic disease management.

The invention provides a nifedipine controlled-release preparation that can put off release and a preparation method thereof. The controlled-release preparation can put off release for a period of time and then can release continuously to prolong the duration of drugs. Patients can take drugs before sleep and effective dose of drugs are released continuously in the morning next day, thus causing the effect of the drugs to be consistent with the rhythm of disease incidents, leading the patients with high blood pressure to safely go through the outbreak period of cardiovascular disease and overcoming the inconvenience that the conventional preparation used for the 'morning peak phenomenon' of the high blood pressure needs to be taken drugs in the wee hours.

The present invention discloses a motion delay and tremor quantitatively detecting device and detecting method, and relates to the field of medical instruments. The motion delay and tremor quantitatively detecting method and device disclosed by the present invention are implemented through cooperation of software in combination with hardware electronic devices. According to the scheme of the present invention, fine pen data input by a subject by using an electronic pen is captured and analyzed through deep learning and big data methods, and the motion time, the median motion speed, the acceleration maximum value, the tremor frequency, the tremor amplitude, and the position (x,y) of the pen during handwriting of the subject, a motion trajectory within 1 cm from the plane written by using the electronic writing input device, dynamics indicators such as the speed and the acceleration, and other data are obtained, so that a solution of an auxiliary detection and medication effect trackingmethod for quantifiable objective indicators of the motion delay and tremor (especially in the early stages) is provided from the perspective of typical motion delay and tremor core symptoms such as the tremor, the motion delay, the spasticity and the like.

The invention belongs to the technical field of veterinary medicines, and particularly relates to a ceftiofur hydrochloride powder injection as well as a preparation method and an application thereof. The ceftiofur hydrochloride powder injection is prepared from the following effective components ceftiofur hydrochloride and a cosolvent at the weight ratio of (48-52) to (28-34). Ceftiofur sodium is replaced with the ceftiofur hydrochloride; veterinary cefepime hydrochloride powder injection is prepared by weighing the effective components and the cosolvent at the weight ratio of (48-52) to (28-34), mixing evenly, and sub-packaging; and the veterinary cefepime hydrochloride powder injection can be produced and stored at a room temperature. According to the ceftiofur hydrochloride powder injection, the problems that an existing veterinary cefepime hydrochloride powder injection needs to be produced by a freeze-drying method, the raw materials and the preparation need to be stored at a low temperature of 4-10 DEG C, the placement time in a room-temperature or high-temperature season is overlong, and the medication effect is poor due to degradation are solved; the prepared powder injection has the same antibacterial effect as a ceftiofur sodium freeze-dried powder injection; and the ceftiofur hydrochloride powder injection is low in cost and wide in application prospect.

The invention discloses a regional collaborative linkage medication management method and system based on an NFC visual smart card. The system disclosed by the invention comprises a collaborative medical platform, a smart drug library system, a hospital management information system, a family doctor subsystem and a patient subsystem, which can separately perform information interaction with the visual smart card. The method comprises the following steps: writing prescription information into the visual smart card at the hospital management information system or through the collaborative medical platform, and using the visual smart card to trigger an electronic label at a position of a smart drug library corresponding to the medicine in the prescription information at the smart drug librarysystem to send medicine withdrawal prompt, and after the medicine withdrawal is completed, performing, the visual smart card and the electronic label, delivery information, and uploading a patient medicine withdrawal record to the collaborative medical platform. During the medication treatment of a patient, the medication effect information is uploaded to the collaborative medical platform through the smart card, the family doctor subsystem and the patient subsystem.

The invention discloses a preparation method of a triptolide nano coating agent. The triptolide nano coating agent is prepared by the following steps: preparation of nanoparticles, freeze drying, preparation of a sol, and preparation of the nano coating agent. The coating agent prepared by the preparation method disclosed by the invention is convenient to use, so that the long-acting control-released medicine effect can be realized, the bioavailability of the medicine is improved, the use level of the medicine is reduced, the toxic and side effects of triptolide are effectively reduced, and the officinal dosage forms of triptolide are enriched.

The invention discloses an improved structure for a health-care cervical pillow. The structure comprises a pillow body with a hollow structure, wherein a thermal conductive baffle plate which is arranged in the pillow body transversely separates the inside of the pillow body into an upper separate space and a lower separate space; a heating device connected with thermal conductive baffle plate is arranged in the lower separate space; an air conductive structure communicated with the inner space of the upper separate space and the outer space of the pillow body is arranged on the wall of the upper separate space; and the heating device comprises a heating element attached to the bottom surface of the thermal conductive baffle plate and a control circuit connected with the heating element. The structure also comprises a voltage regulating device, wherein the voltage regulating device is connected with the control circuit through a power cord. The improved structure for the health-care cervical pillow is a health-care product integrated with medication, thermal therapy and other functions, and has the characteristics of simple structure, safe and convenient use and good medication effect.

The invention discloses a traditional Chinese medicine preparation for treating synovitis, which is prepared for promoting blood circulation by removing blood stasis, relieving inflammation and pains, eliminating blood stasis and promoting tissue regeneration, on the basis of overview of traditional Chinese medicine on synovitis diseases and of modern medicine to pathogenesis and treatment principle. The preparation uses the following pure natural Chinese herbal medicine: pseudo-ginseng, safflower, gardenia, mastix, myrrh, rhubarb, pearl, nutgall and calculus bovis, which are combined according to the theory of traditional Chinese medicine and concocted respectively. The preparation has the advantages of quick medical effect, quick disappearance of clinical symptoms, small toxic and side effects, short treatment course, little pain, low cost and high primary healing rate, and can relieve the pain of a synovitis patient quickly.

The invention relates to an application of medical sponge as a vagina administration carrier and a vagina administration device, in particular to the application of the medical sponge and medical devices manufactured by taking the medical sponge as a main material. The invention also discloses the application of the medical sponge as the vagina administration carrier. The vagina administration device consists of a medical sponge body and a core rod and the medical sponge body is pipe shaped and sheathed on the core rod, wherein the core rod is manufactured by tenacious medical plastics. When in operation, the medical sponge body absorbs liquid medicine which can cure gynecological diseases and the device is placed in the vagina. The medical sponge can cause the medicine to be applied at the affected parts in liquid form and the liquid medicine can be provided to the affected parts for a long time, thus realizing ideal medication effect.

The invention discloses a waste water discharge port for separation processing. A liquid inlet pipe and a liquid outlet pipe are inserted into two ends of the port through screw threads; one end of aseal box is connected to an upper end face of the port in a penetrating way; a liquid storage bin is fixedly connected to the other end of the seal box; a rotating wheel is rotatably connected to an inner rear wall of the port; a plurality of annularly distributed blades are fixedly connected to a side wall of the rotating wheel; one end of a first connecting rod is rotatably connected to a frontwall of the rotating wheel; water pressure enables the rotating wheel to rotate so as to drive a piston block to longitudinally move in a reciprocating way, so that a rotating plate is shaken so as todrive a stirring plate to longitudinally move in a reciprocating way; meanwhile, the piston block pressurizes the liquid storage bin, so that a medicament enters a second connecting pipe and then flows into the liquid outlet pipe so as to be finally mixed with waste water. The medicament can be automatically added into the waste water, the occurrence of the phenomena that the medicament forms a precipitate after long-time standing, the medicine concentration is nonuniform, and a medication effect is influenced can be prevented, and meanwhile, the working efficiency is improved.

The invention relates to a kit for detecting medication effects of clozapine and risperidone by virtue of rs4680 polymorphism, and belongs to the field of gene technology. The invention relates to separated nucleotide which contains a single-nucleotide polymorphism site, wherein the sequence of the nucleotide is as shown in SEQ ID NO: 1; the single-nucleotide polymorphism site is on the 854th position; and rs4680 is as shown from G to A. The invention relates to a method for detecting the nucleotide, wherein the method comprises the following steps: 1, detecting the nucleotide which has the sequence as shown in SEQ ID NO: 1 and is located on the 854th position; and 2, by virtue of a Taqman-MGB typing method, detecting whether single-nucleotide polymorphism exists on the 854th position or not. The kit disclosed by the invention lays a foundation for researching a relation between COMT (catechol-O-methyl transferase) gene polymorphism in China's people and clinical medication safety and provides a theoretical basis for the individualization of clinical medication; and meanwhile, the kit also provides a guidance basis to new drug research and development on the basis of pharmacogenomics concept.

The invention discloses a lotus root powder for preventing epistaxis, which is characterized in that fresh lotus root is used as the main material, combined with daylily flowers, lotus flowers, radices japonicus and rhizome of rhizoma rhizome, and is made through processes such as hydrocyclone separation, hot air drying and the like. Lotus root starch has high nutritional value and good medicinal effect. It is a good food therapy for stopping bleeding and removing blood stasis. Combined with daylilies, lotus, radix radix and Imperatae root, the nutritious lotus root powder can be made to clear away heat and moisten the lungs, dredge wind and collaterals, nourish blood and stop bleeding. , can be eaten for a long time.

The invention relates to a Bola type ribavirin compound. A structure is shown as a general formula I. Through studying the characteristics of the special structure of the Bola type amphiphilic molecules, the structure optimization is performed by aiming at 1, 2, 4-ribavirin; the water solubility and the cancer cell growth inhibition rate of the compound are improved. Further, the compound has the capability of forming nanometer scale particles through self assembly in a water solution, so that the compound can be more easily gathered into the tumor tissues to realize the targeted medication through high permeability of the solid tumor and the retention effect. Meanwhile, as a nanometer medicine carrier, the compound can also encapsulate and seal other micromolecular medicine to reach the combined medication effect. In the general formula, n, R1, R2, R3 and R4 are defined as the patent claim. The formula I is shown as the accompanying drawing.

The invention relates to the technical field of Baidu AI, and specifically relates to a pharmacy member intelligent medicine buying method implemented based on Baidu AI. The method comprises the stepsthat 1, a member enters the pharmacy; 2, the pharmacy calls a Baidu face recognition interface through a camera to obtain membership information; 3, the membership information is pushed to a pharmacyterminal; 4, an assistant checks the pharmacy terminal to understand the illness; 5, the assistant recommends rational medication according to the illness; 6, the member buys the medicine and leavesthe pharmacy; and 7, the pharmacy terminal asks the medication effect at regular time and completes the service closed-loop. The pharmacy member intelligent medicine buying method solves the problemsthat the pharmacy member can enjoy dedicated services without carrying a membership card, the member is recognized through Baidu face recognition, the membership information is obtained in real time,and the assistant can recommend rational medication according to the illness of the member.

The present invention is one novel medicine package for preventing and treating women's cervical virus infection, and the medicine package has novel medicine recipe, novel medicine form and novel medicine transfer device. The medicine package is for treating chronic cervicitis caused by sexually transmitted cervical human papilloma virus (HPV), herpes simplex virus II (HSV-2), cytomegalovirus (CMV), etc and cervical epithelium maldevelopment. It has the functions of inhibiting virus propagation and preventing cervical carcinoma. The present invention has unique medicine recipe, special medicine transfer mode, accurate administration to the pathological cervical part, high local medicine concentration, lasting medicine action period and raised antiviral effect. The cervical Papanicolaou smear examination reveals that the present invention is advance and effective.

The invention provides a pediatric traditional Chinese medicine medication data analysis system. The pediatric traditional Chinese medicine medication data analysis system comprises a data acquisition and preprocessing module, a medication effect recovery module and a data analysis and decision module. The data acquisition and preprocessing module is used for acquiring, preprocessing and classifying traditional Chinese medicine use data and extracting medicine types, medicine doses and medicine use frequencies. The medication effect recovery module recovers the medication effect curve of the medicine in the patient based on the medication dosage. And the data analysis and decision-making module compares the current patient medication data with the effective medication model and the medication model to be observed, updates model data, identifies abnormal data, transfers stable data into the effective model, and discards invalid data. According to the system, accurate analysis of traditional Chinese medicine medication is achieved through multi-dimensional data analysis, medication decision is optimized, and the safety and effectiveness of pediatric traditional Chinese medicine medication are improved. The scientificity and the safety of pediatric traditional Chinese medicine medication can be effectively improved, the abnormal condition of medication is reduced, and the treatment effect is improved.

The invention discloses a tumor ECM degrading and / or inhibiting agent and a complete set kit and application thereof. The tumor ECM degrading and / or inhibiting agent comprises at least two kinds of ananti-hyaluronidase agent, an anti-collagen agent, and an anti-tissue agent. The tumor ECM degrading and / or inhibiting agent can effectively degrade or restrain generation of a tumor extracellular matrix in a broadspectrum manner, and the tumor penetrability is improved, so that drugs can effectively enter tumors to be in contact with and kill tumor cells, and improve the medication effect. The combination manner can be applied in an intratumoral injection manner, so that the applying concentration of single components can be reduced, and the side effect is low. The complete set kit can increase the medication effect, the medicament dose can be reduced, and dosage required for achieving the same effect by an antitumor intratumoral injection manner is lower than that used for venous or other nonintratumoral injection, the antitumor dosage is reduced, and besides, the antitumous effects are increased.

The invention discloses a medicine for preventing and treating motion sickness and Meniere disease and application of mozavaptan in preparation of medicines for preventing and treating motion sickness and Meniere disease. The medicine is prepared from mozavaptan with an effective dosage for preventing and treating motion sickness and a pharmaceutically acceptable carrier. By adopting the mode, the medicine has an effective reference effect in the aspects of prevention and treatment of motion sickness and Meniere disease, further achieves an effective medicinal effect, and has a relatively small side effect.

The invention discloses a graphene far infrared ceramic powder silica gel material, which is prepared from the following raw materials in percentage by mass: 5 to 11 percent of graphene, 29 to 35 percent of far infrared ceramic powder, 10 percent of G10 powder, and 50 percent of medical-grade silica gel. Compared with the prior art, the graphene far infrared ceramic powder silica gel material provided by the invention has the advantages of capability of avoiding side effects caused by current clinical routine medication, obvious curative effect, long medication effect, convenience in use, no toxic and side effects, and capability of effectively treating various acute and chronic swelling pain diseases.

The invention belongs to the field of Chinese medicine application, and particularly discloses a Chinese ointment for treating burn and scald. The Chinese ointment for treating burn and scald is prepared from the raw materials of glycyrrhiza, gynura bicolor, honeysuckle, dandelion, safflower and cordyceps, and is prepared according to a certain weight ratio. The Chinese ointment has no odor, is large in drug loading capacity, good in air permeability, strong in moisture retention, long in medicine action time and fast in transdermal affected part absorption, the pain can be stopped immediately, the curative effect is quick and exact, the pharmaceutical effect is safe, the ointment can be torn and pasted repeatedly, is good in compatibility at the skin affected part, has no excitancy and irritability, and has no toxic and side effects, people feel comfortable in applying the Chinese ointment, the use is convenient, and the skin has no scar after the recovery.