Heavy metal removal method from mineral drug

A mineral medicine and heavy metal technology, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, inorganic active ingredients, etc., can solve the problems of energy consumption, time-consuming, and clean removal of external ingredients, and achieve the effect of increasing drug properties and low cost

Inactive Publication Date: 2006-10-04
LANZHOU UNIVERSITY
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Problems solved by technology

But on the other hand, so far in the production of traditional Chinese medicine, there is no better treatment method except that the traditional Chinese medicine processing method is still used to process mineral medicine.
The mineral traditional Chinese medicine processing methods stipulated in the Chinese Pharmacopoeia, such as: burning moxibustion, water flying, forging, and vinegar quenching, are not only time-consuming, laborious, and energy-consuming, but also produce waste gas and wastewater pollution. More importantly, the use of such methods is not only ineffective. Dissolving mineral traditional Chinese medicine, let alone quantitatively control the content of active ingredients in the medicine, and effectively remove harmful heavy metals in it
Theoretically speaking, mineral traditional Chinese medicine can be dissolved by using chemical methods, but chemical methods often require harsh conditions such as aqua regia, and it is difficult to retain the necessary active ingredients in mineral medicines, thus losing the therapeutic effect of traditional Chinese medicine; on the other hand, using pure chemical methods Drug processing may also introduce components that the drug itself does not have, and even introduce toxic and highly toxic components into the drug. Remove these extra ingredients
[0003] In addition, these traditional Chinese medicine mineral medicines are used in medical practice by themselves or in combination with other medicines to treat diseases. Because the mineral medicines are insoluble in water, there are the following defects in application. First, the active ingredients cannot fully exert their effects; Second, the amount of mineral medicine used is relatively large, and the content of heavy metals and arsenic exceeds the standard; third, mineral medicine is difficult to dissolve in water, so its use is subject to some restrictions, such as difficult to apply in the prescription of injection medicine, etc.
Fourth, it is impossible to quantitatively control the content of active ingredients and harmful substances in drugs

Method used

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  • Heavy metal removal method from mineral drug

Examples

Experimental program
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Effect test

Embodiment 1

[0021] Processed mineral herbal medicines are realgar, cinnabar and natural copper.

[0022] Crush the mineral medicine to about 100 meshes, and then carry out spectrometry on the mineral medicine powder to understand its specific composition.

[0023] Mineral fine powder is then added to the treatment solution according to mineral powder: the treatment solution is a ratio (weight ratio) of 1: 10, the treatment solution wherein contains the basic components of bacterial strains and 9K medium [9K medium basically consists of: each 1000 ml culture medium containing (NH 4 ) 2 SO 4 3.0g, KCl 0.1g, K 2 HPO 4 0.5g, MgSO 4 7H 2 O 0.5g, Ca(NO 3 ) 2 0.01g, FeSO 4 7H 2 [044.7g], wherein the strains used are: Thiobacillus ferrooxidans, Thiobacillus thiooxidans and Leptospira ferrooxidans are combined in equal proportions, and the inoculum size is 10%.

[0024] After stirring the mineral powder and the treatment solution evenly, use 25% dilute sulfuric acid solution to adjus...

Embodiment 2

[0032] Processed mineral herbal medicines are realgar, cinnabar and natural copper.

[0033] The mineral medicine is pulverized into different particle sizes, and the mineral medicine is processed according to the processing method of Example 1, and the results are shown in Table 3

[0034] mineral medicine

[0035] Cinnabar

Embodiment 3

[0037] Processed mineral herbal medicines are realgar, cinnabar and natural copper.

[0038] Mineral medicine was crushed into 80 meshes, mineral powder and treatment liquid in the system were added in different proportions, and realgar, cinnabar and natural copper were treated according to the treatment method of Example 1. The results are shown in Table 4.

[0039] mineral medicine

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Abstract

The invention discloses a process for processing mineral medicaments such as cinnabar, orpiment, native copper, magnetite, and reddle, especially the method for dissolving and removing hazardous materials in the medicaments, which comprises processing the minerals with bacteria, dissolving the minerals insoluble to water into aqueous solutions under the action of bacteria, then removing unwanted ions in the solution through chemical or physical methods.

Description

technical field [0001] The present invention relates to a treatment method for traditional Chinese medicine ore medicine (referring to mineral medicine in traditional Chinese medicine and other ethnic medicines), more precisely, it is a kind of treatment method for using bacteria to treat insoluble mineral medicine, such as: cinnabar, realgar, natural copper , Magnet, substitute ocher, etc., become soluble components and dissolve into the solution, and remove harmful substances. Background technique [0002] In addition to a large number of herbal medicines and animal medicines, the Pharmacopoeia of Chinese Medicine also contains many mineral medicines, such as: cinnabar, realgar, natural copper, magnet, ochre, etc. In Chinese medicine practice, the unique effects of these drugs are used to treat various diseases in combination with other drugs. However, due to the excessive amount of heavy metal harmful ingredients contained in mineral medicines, its use is subject to some...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/00C12P1/04
Inventor 李红玉张景红支德娟
Owner LANZHOU UNIVERSITY
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