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Medicine composition and preparation containing effective components of gastrodia tuber and Chuanxiong rhizome

A technology of active ingredients and pharmaceutical preparations, which is applied in the field of pharmaceutical compositions and preparations containing active ingredients of Gastrodia elata and Rhizoma Chuanxiong, can solve problems such as difficult quality control, unstable active ingredient content, heavy metal pesticide residues, etc., and achieve safety issues, The content of active ingredients is clear and the effect is quick

Inactive Publication Date: 2006-11-08
欧苏 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This new medication helps make medicine faster by giving it all its benefits without containing any unnecessary substances like tampons. It also includes specific components which help reduce side-effects such as staining clothing during administration.

Problems solved by technology

This patented technical problem addressed in this patents describes various methods for obtaining effective drugs from plants called Gymnema sppage Linnate Necklacea that contains many important biologically relevant molecules like gamma sterone, triterpene lactones, flavonoids, carboxylic acids, amino acids and lignans. These chemical agents play an essential role during life cycle stages including regulating blood flow, improving cognitive function, reducing pain sensitivity, treatments related illnesses, preventive therapy against stroke symptoms, relaxed nerve conductions after injury, immunotherapies targeting specific proteins involved in arterious disorders, chemophoresis, tranquilizers, suppression of clotting, calcium channel blockers, thrombaudinators, and servoisnector blocks.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Gastrodin 10g

[0025] Ligustrazine Hydrochloride 20g

[0026] 0.1mol / L hydrochloric acid appropriate amount

[0027] Add water for injection to 1000ml

[0028] Preparation method: Dissolve ligustrazine hydrochloride and gastrodin in about 800ml water for injection at 80°C, adjust the pH with 0.1mol / L hydrochloric acid, add water for injection to the full amount, filter and divide into 2ml ampoules, and sterilize with flowing steam (100 ℃, 30 minutes), to obtain the injection of the present invention.

Embodiment 2

[0030] Gastrodin 20g

[0031] Sodium Ferulate 25g

[0032] Mannitol 10g

[0033] 0.1mol / L hydrochloric acid appropriate amount

[0034] Add water for injection to 1000ml

[0035] Preparation method: Dissolve sodium ferulate, gastrodin and mannitol in about 800ml water for injection at 80°C, adjust the pH with 0.1mol / L hydrochloric acid, add water for injection to the full amount, filter and divide into 5ml vials, freeze Dry to obtain powder needle.

Embodiment 3

[0037] Gastrodin 100g

[0038] Ligustrazine Hydrochloride 50g

[0039] Starch 100g

[0040] Sodium Carboxymethyl Cellulose 40g

[0041] PVP1.5% solution appropriate amount

[0042] Magnesium Stearate 5g

[0043] Makes 1000 formulation units

[0044] Preparation method: Mix ligustrazine hydrochloride, gastrodin, starch, and sodium carboxymethylcellulose evenly, add PVP1.5% solution to make a soft material, ventilate and dry at about 60°C, granulate, add magnesium stearate and mix well , made into tablets, orally disintegrating tablets, granules, capsules, etc. according to conventional preparation methods.

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PUM

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Abstract

The present invention discloses a kind of medicine composition containing the effective components of gastrodia tuber and Chuanxiong rhizome and its medicine preparation. The effective components of gastrodia tuber extract include liposoluble components and water soluble components, and are gastrodine, gastrodine aglycon, acetyl gastrodine and vanillyl alcohol. The effective components of Chuanxiong rhizome extract include liposoluble components and water soluble components, and are ligustrazine, ferulic acid and their derivatives. The medicine composition may be prepared into various pharmaceutically acceptable preparation forms, such as tablet, dispersant tablet, capsule, etc. The combination of effective components from gastrodia tuber and that from Chuanxiong rhizome makes the medicine composition and its medicine preparation possess controllable quality and high curative effect.

Description

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Claims

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Application Information

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Owner 欧苏
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