Red flavonid and production process of its medicine composition

A technology for total red flavonoids and medicines, which is applied in the field of medicine, can solve the problems such as few production process researches, and achieves the effects of stable preparation, stable process and low process cost.

Inactive Publication Date: 2006-11-08
福州屏山制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is also little research on the product

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 540 grams of a little red, add appropriate amount of water (about 980 grams), heat and boil for about 1.5 hours, filter out the liquid medicine, add appropriate amount of water to the medicine dregs, heat and boil for about 1.5 hours, combine the two filtrates, concentrate to a clear paste (50 ℃ heat test When the relative density is 1.10 ~ 1.15).

[0028] Take an appropriate amount of the above-mentioned clear ointment, add water to dissolve, add dilute sulfuric acid to heat and reflux for hydrolysis, let it cool, and extract it with ethyl acetate as the test sample. main ingredient.

Embodiment 2

[0030] 10 kg of a little red, 7.5 kg of goldenrod, 0.63 kg of ginger, and 6.25 kg of Radix Banlangen, take a little red, goldenrod and ginger, put them in an extractor, add water and boil twice, each time for 1.5 hours, combine the decoction, and let it stand. Concentrate the supernatant into a clear paste. Take another Radix Radix, add water and decoct twice, each time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate into a clear paste (relative density when measured at 50°C is 1.10-1.15), add ethanol to make the alcohol content reach 60% , stand overnight, filter, and the filtrate is concentrated into a clear paste after recovering ethanol. The clear pastes obtained above were combined and concentrated into a thick paste (the relative density was 1.30-1.40 when thermally measured at 80°C).

Embodiment 3

[0032] The thick paste obtained in Example 2 is heated and stirred according to the concentration ratio of paste: purified water=1: 1.1 (weight ratio), fully dissolved, and passed through an 80-mesh sieve as a binder.

[0033] Take another 3.75 kg of licorice, grind it into a fine powder, and pass through a 100-mesh sieve. Get another 0.45 kg of dextrin. Put the licorice fine powder and dextrin into the granulator, after fully mixing, carry out one-step granulation with the above-mentioned prepared binder as the spray liquid and take it out after drying for 30 minutes, after the moisture content is determined to be qualified (moisture content 3-7 %) to obtain dry particles.

[0034] Add magnesium stearate according to 5 / 1000 of the weight of the dry granules, mix well, and then compress into tablets to make 10,000 tablets.

[0035] The prescription composition of the present invention belongs to clinical experience prescription, and curative effect is definite and stable. T...

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PUM

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Abstract

The present invention relates to the production process of effective Chinese medicine component, and is especially production process of tassel flower herb flavones. The present invention also relates to the production process of one medicine with function of clearing away heat and toxic material, and the medicine may be used in treating common cold, influenza, parotitis, laryngopharyngitis and other diseases. The present invention has simple preparation process, excellent preparation stability, extracts liquid as adhesive and excellent technological result.

Description

technical field [0001] The invention relates to a production method of active ingredients of traditional Chinese medicine, in particular to a production method of chemical ingredients of total flavonoids (Flavones) of Chinese medicine Yidianhong. The invention also relates to a production method of a medicine with heat-clearing and detoxifying effects, and the medicine can be used for treating diseases such as cold, influenza, parotitis, pharyngitis, tonsillitis or tracheitis. The invention belongs to the field of medicine. Background technique [0002] Compositae plant a little red, is a kind of herbal medicine commonly used to treat inflammation, mosquito bites, conjunctivitis, rheumatism, trauma, etc. It contains pyrrolizidine alkaloids and flavonoids, and flavonoids are its anti Active ingredient with anti-inflammatory and antioxidant effects. [0003] The content of flavonoids in a little red is relatively high, and flavonoids are a kind of compounds with strong physi...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P11/00A61P11/04A61P11/14A61P31/12A61P31/16
Inventor 王跃仁
Owner 福州屏山制药有限公司
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