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Treatment of diseases

A disease, neurological disease technology, applied in a method and composition for restoring or improving neurotransmitter, disease drug, treatment of non-demyelinating neurological disease, group of autoimmune diseases field, able to solve slow and other problems

Inactive Publication Date: 2007-04-25
AIMSCO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Furthermore, such an activity is expected to act relatively slowly

Method used

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  • Treatment of diseases

Examples

Experimental program
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Embodiment Construction

[0040] Example of production of goat serum

[0041] Goats were inoculated by intramuscular injection of a lysed HIV virus mixture in Freund's adjuvant. The virus was first heat killed at 60°C for 30 minutes. After an appropriate time interval, such as 2 weeks, blood samples are drawn for initial evaluation. In the optimized protocol, goats were injected weekly for 4 weeks, and then blood was drawn from the animals at 6 weeks to obtain the agent.

[0042] Under aseptic technique, approximately 400 cc of blood was extracted from the goat. The area for needle extraction was shaved and prepared with povidone-iodine. An 18-gage needle was used to extract approximately 400 cc of blood from the animal. It should be noted that animals tolerated the withdrawal of approximately 400 cc of blood without suffering any adverse effects. The animals do not have to be sacrificed. The animal can then be bled again approximately 10-14 days after it has replenished its blood volume.

[004...

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PUM

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Abstract

Methods of treatment of various non-demyelinating and demyelinating neural disorders are provided, comprising administering a serum composition obtained from a goat after challenge with an immunogen. Also provided are methods of treatment of certain autommune disorders using such a composition.

Description

field of invention [0001] The present invention relates to methods and compositions for the treatment of neurological disorders. In particular, but not exclusively, the present invention relates to methods and compositions for restoring or improving neurotransmitters in damaged nerve cells. Certain aspects of the invention relate to methods and compositions for treating non-demyelinating neurological diseases. Other aspects of the invention relate to methods of treating an autoimmune disease selected from the group consisting of lupus, psoriasis, eczema, thyroiditis, and polymyositis; and certain aspects of the invention relate to methods for treating Drugs for such diseases. Background of the invention [0002] PCT publications WO03 / 004049 and WO03 / 064472 describe therapeutic agents and treatments based on serum compositions with a number of surprising beneficial effects. The respective contents of each of these two documents are hereby fully incorporated by specific ref...

Claims

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Application Information

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IPC IPC(8): A61P25/00A61P25/28A61P37/00A61P17/06A61K39/395A61K39/42C07K16/06C07K16/10
Inventor B·尤尔
Owner AIMSCO LTD
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