Injection preparation and use

A technology of injection needles and injections, applied in the field of biomedicine, can solve the problems of epilepsy mechanism not very clear, patient injury and pain, behavior out of control, etc., and achieve the effect of small drug dosage, no drug residue, and fast action
CN1977828AInactive Publication Date: 2007-06-13ιŸ©θ‹
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
ιŸ©θ‹
Publication Date
2007-06-13
Estimated Expiration
Not applicable Β· inactive patent
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Abstract

The present invention relates to an injection preparation containing thyrotropin releasing hormone (TRH). The effective component contained in said injection preparation is an artificially-synthetic 3 peptide substance, it is made up by connecting pyroglutamic acid, histidine and praline, its chemical composition is pGlu-His-Pro, its molecular formula is C16H21N5O5 and its molecular weight is 363.4 daltons. Said injection preparation can be used for curing the diseases due to HRH neurohormone imbalance, epilepsia, depression and others.
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Description

technical field

[0001] The present invention relates to the application of a kind of synthetic thyrotropin releasing hormone (ThyrotropinReleasing Hormone, abbreviated TRH), its chemical composition is by pyroglutamic acid-histidine-proline (pGlu-His-Pro), molecular weight is 363.4 Daltons, molecular formula C 16 h 21 N 5 o 5 3-peptide substances. The substances containing TRH components are prepared into injections for the treatment of diseases caused by the imbalance of TRH neurohormones. It can be used clinically for anti-shock and wakefulness promotion, epilepsy, depression, postpartum lack of milk, and children's mental retardation. Treatment. The invention belongs to the field of biomedicine. technical background

[0002] Thyrotropin-releasing hormone (TRH) is a tripeptide substance secreted by the hypothalamus, and it is also the smallest functional peptide fragment found so far. It reaches the anterior pituitary through the pituitary-portal system, and it has t...

Claims

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