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Antiperspirant formulations

a technology of antiperspirant formulations and antiperspirant, applied in the direction of drug compositions, disinfection, pharmaceutical delivery mechanisms, etc., can solve the problems of reducing the effectiveness of antiperspirant formulations, increasing the visible whiteness of such formulations, and no simple matter to reformulate antiperspirant formulations with alternative oils, and achieve excellently low visible deposits

Inactive Publication Date: 2002-04-04
UNILEVER HOME & PERSONAL CARE USA DIV OF CONOPCO IN C
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0021] By the choice of such a combination of carrier fluid components and structurant, it has been possible to obtain antiperspirant sticks showing excellently low visible deposits.

Problems solved by technology

However, many conventional fatty alcohol or other wax structured sticks tend to leave visible white deposits on application to human skin, and likewise, visible deposits can also be transferred onto clothing by physical contact with the skin.
Although volatile silicone oils enable the antiperspirant formulations to exhibit many desirable properties, there are two consequences of employing them as the principal component of the carrier fluid, namely that such antiperspirant formulations tend to exhibit comparatively high visible whiteness when they are topically applied and also the visible whiteness of such formulations tends to increase further with the passage of time.
However, it is no simple matter to reformulate antiperspirant formulations with alternative oils.
Whilst many oils have been accepted within the industry as minor components of a volatile-silicone-based carrier fluid, the very properties which have rendered them suitable to be considered suitable as emollients have been thought to render them unsuitable as the principal carrier oil.
Accordingly, although such specifications assert that they provide formulation exhibiting low visible deposits, this assertion is often judged against those sticks which were commercially available when the applications were sought and in practice, there often remains considerable room for improvement and do not provide adequate teaching to the skilled formulator to enable that person to choose effectively.
For the reasons of colour, odour and irritancy identified hereinbelow, it is undesirable to employ methoxy cinnamates in compositions intended for use by the general public, so the skilled man would be prejudiced against this text.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

Wax Structured Opaque Sticks

[0200] The formulations made in Example 1 and their properties are summarised in Table 1 below.

[0201] CWS=Commercially available conventional white solid stick, structured with waxes (stearyl alcohol+castor wax) employing a mixture of volatile silicone oils as the principal carrier fluid.

[0202] ISS=Commercially available solid stick with lower visible deposits, structured with waxes (stearyl alcohol+castor wax) and employing as carrier fluid a mixture of volatile silicone oils (refractive index of about 1.4) with a non-volatile masking oil (refractive index of below 1.465) (Fluid AP) at a weight ratio of about 4:1.

[0203] nm=measurement not made

[0204] Comp CA: Stick cracked and fell apart, so that no characterisation measurements could be made.

2TABLE 1 Comp Comp Comp Comp Ex Ex Ex Ex CWS ISS CA CB 1.1 1.2 1.3 1.4 Syncrowax (1) Castorwax (2) 4.5 4.5 5 4 3 4.5 K82H (3) 13.5 13.5 15 12 9 13.5 AZAG 7167 (8) 24 24 24 24 24 24 Finsolv TN 11.4 22.8 55 59 63 57 (1...

example 2

Opaque Sticks Structured with a Non-polymeric Fibre-forming Gellant Alone or With a Wax

[0206] The formulations and resultant properties of sticks made in Example 2 are summarised in Table 2 below.

3TABLE 2 Ex Ex Ex Ex Ex Ex Ex Ex Ex 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 12-HSA (6) 6 6 6 6 6 6 6 6 GP-1 (7) 6 K62 (4) 8 8 8 8 K82H (3) 8 8 8 8 AZAG 7167 (8) 24 24 24 24 24 24 24 24 24 Finsolv TN 61 34.9 48.8 36.6 61 48.8 42.7 36.6 55.2 (10) DC245 (11) 6.1 12.2 24.4 12.2 18.3 24.4 Eutanol G 13.8 (15) Perfume 1 1 1 1 1 1 1 1 1 Penetrometer 10.4 12.9 11.1 11.7 9.8 9.4 10.1 10.5 16.5 Hardness (mm) Whiteness on n / d 24.4 21.8 24.9 22.1 22.1 21.5 23.3 21.3 Black Wool Whiteness on n / d 32.6 33.6 35.6 31.2 33.4 34.5 33.3 23.1 grey abrasive paper Ex Ex Ex Ex Ex Ex Ex Ex Ex 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 12-HSA (6) 6 4 GP-1 (7) 2 6 6 Montan Acid 6 3 Wax (17) K82H (3) 10 10 10 8 8 AZAG 7167 (8) 24 24 25 25 24 24 24 24 24 Finsolv TN 53.6 66.0 65 60 47.2 41.3 35.4 59 (10) Finsolv BOD 61 (20)...

example 3

Non-opaque Sticks

[0208] The formulations and resultant properties of sticks made in Example 3 are summarised in Table 3 below.

4 TABLE 3 Ex 3.1 Ex 3.2 Ex 3.3 Ex 3.4 Ex 3.5 Ex 3.6 12-HSA (6) 106 6 GP-1 (7) 6 6 6 2 2 AZAG 7167 24 24 (8) AACH A418 20 20 20 20 (18) Finsolv TN 70 74 64 67 20.4 (10) Prisorine 10 7 3515 (16) Eutanol G (15) 13.6 DC704 (14) 47.6 54.4 RI AP Active 1.534 1.534 1.534 1.534 1.562 1.562 RI Solvent 1.4841 1.4841 1.4803 1.4814 1.5343 1.5312 Penetrometer 11.9 12.9 Nm 12.5 3.6 10.4 Hardness (mm) Whiteness on nm 16.3 Nm 16.2 16.0 18.0 Black Wool Whiteness nm 32.7 Nm 35.8 26.5 26.6 on grey abrasive paper

[0209] All of the sticks made in Example 3.1 to 3.6 were all slightly translucent in appearance and left virtually no white deposits when applied to skin.

EXAMPLE 4

[0210] Further wax-structured sticks were made in accordance with the general procedure of Example 1 and as summarised in Table 4 below (n / d=test not carried out).

5TABLE 4 Ex Ex Ex Ex Ex Ex Ex 4.1 4.2 4.3 4.4 4...

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Abstract

Anhydrous antiperspirant formulations in which a particulate antiperspirant active is suspended in a carrier fluid can result in significant visible deposits when applied to skin or when transferred onto clothing. Anhydrous antiperspirant suspension sticks which exhibit very low visible deposits are obtainable by employing a carrier fluid in which at least 45% and preferably at least 60% of its weight comprises an oxygen-containing emollient oil having a refractive index of at least 1.465, in conjunction with structurant comprises a wax or a non-polymeric fiber-forming gellant, excluding certain gellants or gellant combinations. Preferred emollient oils include alkyl benzoates and alkylphenylsiloxanes. The waxes can even comprise fatty alcohols.

Description

[0001] The present application relates to antiperspirant formulations, and in particular to antiperspirant stick formulations.BACKGROUND AND PRIOR ART[0002] Topically applied antiperspirant compositions are in widespread use throughout much of the world, in order to enable their users to avoid or minimise visible wet patches on their skin, especially in axillary regions. Antiperspirant formulations containing astringent metal salts such as aluminium or zirconium salts commonly act also as deodorants. Antiperspirant formulations have been produced or proposed for use in several physical forms, such as solids, gels, soft solids, creams, lotions and particulate mixtures and these forms can be applied using a range of different dispensers, including aerosol, roll-on, pump spray, sticks, and barrel dispensers, in accordance with the individual preferences of consumers. In some parts of the world, solid formulations in stick form are especially popular, the stick usually being dispensed f...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/28A61K8/33A61K8/365A61K8/37A61K8/44A61K8/891A61Q15/00
CPCA61K8/0229A61K8/042A61K8/28A61K8/33A61K8/365Y10S424/05A61K8/375A61K8/44A61K8/891A61K2800/31A61Q15/00A61K8/37
Inventor FRANKLIN, KEVIN RONALDTURNER, GRAHM ANDREW
Owner UNILEVER HOME & PERSONAL CARE USA DIV OF CONOPCO IN C
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