36 results about "Cinnamates" patented technology

The application relates to the technical field of injection molding demolding master batches, in particular to a polyester transparent injection molding demolding master batch and a preparation method and application thereof. According to mass proportions, 85% to 97% of a carrier and 3% to 15% of a lubricant are included; the lubricant includes zinc bungarotoxin, zinc cinnamate and octadecyl octadecanoate with a mass ratio of (2 to 6):(2 to 6):(1 to 4). The lubricant with the specific component ratio improves the fluidity and demolding property of the polyester product and reduces the haze.

The invention relates to the technical field of biological medicine, in particular to application of esterified derivatives of methyl p-hydroxycinnamate in preparation of antitumor drugs. Experiments show that the derivative has an obvious inhibition effect on the cell viability of tumor cells such as gastric cancer, nasopharynx cancer and breast cancer, particularly has obvious proliferation, migration and invasion inhibition ability on the gastric cancer cells, can induce apoptosis of the gastric cancer cells, has relatively low toxic and side effects, and provides a new medicine for treating the gastric cancer.

The present invention relates to a composition comprising: 1) at least one inorganic UV filter selected from titanium dioxide; 2) at least one α-cyanodiphenylacrylate derivative of the given formula; and 3) at least one 4-hydroxybenzylidenemalonate or 4-hydroxycinnamate derivative of the given formula. The present invention also relates to a cosmetic method for treating skin against UV radiation using said composition.

The invention discloses a multi-scene deodorizing detergent composition and a preparation method thereof, and relates to the technical field of daily chemical industry. The multi-scene deodorizing detergent composition provided by the invention is prepared from the following core components: alkyl glycoside, sodium lauroamphoacetate, tea saponin, hydroxypropyl-beta-cyclodextrin, chitosan, compound enzyme, sodium cinnamate, dragon fruit extract, humulus lupulus extract and the like. Through the synergistic effect of all the components, the composition realizes integration of multiple effects: the irritation is remarkably reduced and the skin barrier is maintained while efficient decontamination is realized; an adsorption-degradation system formed by hydroxypropyl-beta-cyclodextrin, chitosan and compound enzyme can radically remove peculiar smell and efficiently degrade pesticide residues; the chitosan and the pitaya extract synergistically chelate heavy metal ions; and components such as sodium cinnamate have natural whitening and broad-spectrum preservative functions. The technical limitation that a traditional product is single in function is broken through, and a comprehensive and safe washing solution with a positive skin care effect is provided.

An objective of the present invention is to provide a photosensitive organic insulating composition having sufficient absorption, even of i-line radiation, as a photosensitive organic insulating composition that has little influence on device reliability and that is capable of forming a gate insulating film for transistors. An objective of the present invention is also to provide a gate insulating film and a transistor. A photosensitive organic insulating composition according to one embodiment of the present invention contains a chalcone compound and polyvinyl cinnamate.

The present invention discloses a composition and method for treating arthritis. The composition comprises a binary blend of molecules including citral, methyl cinnamate, and epicurzerenone. The binary blend exhibits synergistic efficacy in modulating inflammatory cytokines. The citral, epicurzerenone, and methyl cinnamate, are derived from essential oils of Cymbopogon citratus, Hedychium spicatum, and Zanthoxylum armatum, respectively. Both individual and binary blend exhibits downregulation of pro-inflammatory cytokines IL-2, IL-6, and TNF-α, and upregulation of anti-inflammatory cytokine IL-10

This invention generally relates to the use of hydroxycinnamic acid or its derivatives, such as alginate, in cosmetic or therapeutic settings. The invention further relates to compositions comprising hydroxycinnamic acid or its derivatives.

The present invention provides a repellent composition for mites which is excellent in mite-repelling effect against indoor mites even after a long period of time and is also excellent in safety to humans and animals. The present invention relates to a repellent composition for mites, which contains: (a) 1,8-cineol and / or 1,4-cineol and (b) a perfume ingredient, wherein the perfume ingredient contains one or two or more kinds of perfume compounds having a logP value of 2.0 to 5.5. The mixing ratio (a) / (b) of the (a) ingredient to the perfume compounds contained in the (b) ingredient is set to 5 to 100 on a mass basis. The perfume compounds contained in the (b) ingredient are at least one selected from the group consisting of ethyl cinnamate, allyl caproate, 3-methyl-5-phenyl-1-pentanol, citronellol, δ-dodecalactone, β-ionone, benzyl benzoate, linalyl acetate, geranyl acetate, tricyclo decenyl propionate, benzyl salicylate, limonene, and amyl salicylate.

The present application provides use of compounds represented by formula (I) and formula (II) in the preparation of drugs for improving male reproductive ability. In the present application, different oligoasthenospermia models are constructed, and the improvement effects of the compounds represented by formula (I) and formula (II) on male reproductive ability impairment are verified by means of sperm count analysis, sperm motility analysis, mRNA expression level analysis of inflammatory and antioxidant genes, testicular histopathological damage analysis, etc. The experimental results show that the compounds represented by formula (I) and formula (II) increase the sperm count in mice with oligoasthenospermia, improve the sperm motility of the mice with oligoasthenospermia, ameliorate testicular histopathological damage in the mice, suppress the expression of inflammatory factors, and increase the expression of antioxidant genes, demonstrating great potential in the treatment of oligoasthenospermia.

This invention belongs to the field of polyether polyol synthesis technology, specifically relating to bio-based high-strength polyether ester polyols and their preparation methods. The bio-based high-strength polyether ester polyol is obtained from the following raw materials: small molecule polyol, catalyst, bio-based epoxide, and bio-based phenyl ester compound; the bio-based epoxide is one or more of limonene epoxide, α-pinene oxide, and caryophyllene oxide; the bio-based phenyl ester compound is one or two of benzyl benzoate and benzyl cinnamate. The raw materials used in this invention can be obtained through natural plant extraction, achieving full bio-based polyether ester polyol production, thus fundamentally reducing dependence on fossil resources. By introducing a large number of cyclic and benzene ring structures into the polyol molecule, the resulting product is applied in the field of rigid polyurethane foam, increasing the content of rigid groups in the molecular chain structure, and significantly improving the strength of rigid polyurethane foam compared to traditional polyether polyols.

The application discloses a kind of strawberry wine and its brewing method, adopt first Angelus yeast SY after Angelus yeast RW fermentation after the strawberry wine aroma compound content of aging is ester > alcohol > acid > other > terpene class.SY+RW fermentation of strawberry wine aroma compound content is ester > alcohol > other > acid > terpene class, it is rich in the complexity of wine aroma, give fruit wine more elegant and unique aroma;Wherein, in the fermentation of Angelus yeast SY, the highest OAV value of isoamyl acetate is given, and the main fermentation stage of wine body presents the rich banana aroma;In the fermentation stage of Angelus yeast RW, the content of ester is more, wherein the highest OAV value of ethyl decanoate and isoamyl acetate is given, and the rich pineapple, banana aroma of post-fermentation stage of wine body is given;With the progress of fermentation, the highest OAV value of ethyl cinnamate and phenylethanol is reached, and the rose flower fragrance and sweet amber paste fragrance of strawberry wine aging stage are given, and accompanied by the original aroma of strawberry fruit.

The application belongs to the field of natural product chemistry and medicinal chemistry, and discloses 10,11-dehydrovariecolin cinnamic acid derivatives, a preparation method and purposes thereof. The preparation method takes 10,11-dehydrovariecolin from a fungus as a starting material, and the target derivative is prepared by esterification reaction of the 5-position hydroxyl group of the starting material with cinnamic acid. The series of compounds show good bacteriostatic activity and antitumor activity, and can be used for preparing antitumor drugs or antibacterial drugs.

Sunscreen-effective active ingredient combinations made up of (a) one or more cinnamic acid derivatives of formula (1a) and (1b) in which the groups X, Y and R can be chosen independently from the group hydrogen, and branched or unbranched C1-C 18 Alkyl, and (b) 4-Hydroxyacetophenone.

The application provides a fluorescent probe based on a cinnamic acid derivative as well as a synthesis method and application thereof, and relates to the technical field of synthesis of specific probes. The fluorescent probe is prepared by introducing benzyl bromide into the hydroxyl group of a modified structure compound FHA using p-hydroxycinnamic acid as raw material, and a novel bifunctional fluorescent probe capable of specifically detecting Al 3＋ and N2H4 is developed. The application overcomes the defects of the prior art, the probe can specifically detect Al 3+ and N2H4, and has the characteristics of low detection limit, short response time, wide pH application range and the like; the probe has the characteristics of good biocompatibility, small toxicity, good optical properties and the like, and can be applied to cell imaging experiments.

This invention relates to the field of biotechnology, and discloses an engineered *Yarrowia lipolytica* strain that produces p-coumaric acid using glucose as a substrate, its construction method, and its applications. Construction method: A tyrosine ammonia-lyase gene is integrated using a CRISPR / Cas9 localization and integration method. TAL In *Yarrowia lipophila* strains, the DAHP synthase gene was enhanced. ARO4 , DHS1 and AROG Overexpression of tyrosine synthase TYR Genes and histidine phosphotransferases HIS5 The protease gene was further integrated to synthesize exogenous phenylalanine deamination and hydroxylation pathway genes for p-coumaric acid, including phenylalanine ammonia-lyase gene, cinnamate hydroxylase gene, and P450 reductase gene. The p-coumaric acid produced by the engineered *Yarrowia lipolytica* strain of this invention can reach a maximum yield of 1.7 g / L in shake flasks, and a yield of 30 g / L in a 5 L fed-batch fermentation tank, demonstrating significant industrial application value.

This invention discloses a photosensitive resin composition for use as an alignment agent, the composition comprising: (A) a dianhydride monomer containing a photosensitive group, wherein the photosensitive group is selected from at least one of cinnamate, chalcone, anthracene, coumarin, or benzophenone; (B) a hydrogen donor diamine monomer; and (C) an aliphatic diamine monomer. This invention uses a self-initiating photosensitive resin composition to replace formulation systems relying on exogenous photoinitiators, introducing long alkyl chains into the polyimide molecular chain, which are complementary to the liquid crystal molecular structure, enhancing the interfacial anchoring energy, stabilizing the liquid crystal pretilt angle, and thus maintaining a stable display response time.

The invention relates to the technical field of cloth preparation, and provides a manufacturing process of antistatic grey cloth. The invention relates to an antistatic gray fabric which is obtained by sequentially carrying out padding treatment on a gray fabric through an antistatic finishing agent and an anti-ultraviolet finishing agent, the anti-ultraviolet finishing agent is prepared from the following components in parts by weight: 20 to 25 parts of 2-hydroxy-4-methoxy-5-benzophenone sulfonate, 5 to 6 parts of 4-methoxy isoamyl cinnamate, 15 to 18 parts of zinc oxide, 2 to 4 parts of a surfactant, 1 to 3 parts of a de-foaming agent, 3 to 6 parts of a methoxy-containing phenolic compound, 15 to 20 parts of ethanol and 80 to 85 parts of water; the phenolic compound containing the methoxy group comprises 2-methoxy-4-methylphenol and 4-ethyl-2-methoxyphenol, and the weight ratio of the 2-methoxy-4-methylphenol to the 4-ethyl-2-methoxyphenol is (1-9): 1. According to the technical scheme, the problem that the anti-ultraviolet performance of the gray fabric is poor in the prior art is solved.

The invention provides a liquid crystal aligning agent for forming a weak anchor film, a method for manufacturing a liquid crystal alignment film and a method for manufacturing a liquid crystal element. The liquid crystal alignment agent for forming a weak anchor film can form a liquid crystal alignment film for obtaining a liquid crystal element which has good liquid crystal alignment property and alignment uniformity and can be driven at a low voltage while having high brightness. The liquid crystal aligning agent for forming the weak anchor film is used for forming the weak anchor liquid crystal aligning film, and comprises a polymer (P), the polymer (P) has at least one selected from the group consisting of a specific cinnamate structure, a specific partial structure having a nitrogen-containing aromatic heterocyclic ring, an azobenzene structure, a chalcone structure, a coumarin structure, and a chromanone structure.

The invention discloses phenylalanine ammonia lyase and application of the phenylalanine ammonia lyase in preparation of S-type beta-amino acid. Compared with an amino acid sequence as shown in SEQ ID NO: 1, the amino acid sequence of the phenylalanine ammonia lyase comprises one or more amino acid residue differences in the following sites: the 147th site, the 244th site, the 251st site, the 314th site, the 333th site and the 342nd site. The S-type beta-amino acid is prepared by adopting a mutant of phenylalanine ammonia lyase from streptomyces and taking cinnamic acid or a derivative thereof as a substrate, and the regioselectivity, the enantiomer selectivity and the conversion rate of the product are all remarkably improved.

The application discloses a hydroxyl cinnamic acid alkoxyl alcohol ester derivative and application thereof in cosmetics. Specifically, the application provides a hydroxyl cinnamic acid alkoxyl alcohol ester derivative which is a compound as shown in formula I. The compound provided by the application has good oil phase solubility, high stability in a system, and one or more effects such as antioxidation, whitening and ultraviolet absorption.

A composition for inhibiting sebum secretion is disclosed. The composition contains 3,4,5-trimethoxycinnamate thymol ester, a stereoisomer, pharmaceutically acceptable salt, hydrate, or solvate thereof as an active ingredient. The composition can inhibit sebum secretion in the skin or scalp, and further has useful effects such as the prevention or improvement of seborrheic dermatitis, seborrheic scalp dermatitis, or acne, or the tightening of pores. Methods for inhibiting sebum secretion employing 3,4,5-trimethoxycinnamate thymol ester, a stereoisomer, pharmaceutically acceptable salt, hydrate, or solvate are disclosed.

The invention provides a fluorescent probe based on a cinnamic acid derivative as well as a synthesis method and application of the fluorescent probe, and relates to the technical field of synthesis of specific probes. The fluorescent probe is a novel bifunctional fluorescent probe capable of specifically detecting Al < 3 + > and N2H4, which is developed by taking p-hydroxycinnamic acid as a raw material and introducing benzyl bromide into a hydroxyl site of a modified structural compound FHA. The probe overcomes the defects in the prior art, can specifically detect Al < 3 + > and N2H4, and has the characteristics of low detection limit, short response time, wide pH application range and the like; and the probe has the characteristics of good biocompatibility, low toxicity, good optical property and the like, and can be applied to cell imaging experiments.

The present invention discloses a composition and method for treating arthritis. The composition comprises a binary blend of molecules including citral, methyl cinnamate, and epicurzerenone. The binary blend exhibits synergistic efficacy in modulating inflammatory cytokines. The citral, methyl cinnamate, and epicurzerenone, are derived from essential oils of Cymbopogon citratus, Hedychium spicatum, and Zanthoxylum armatum, respectively. Both individual and binary blend exhibits downregulation of pro-inflammatory cytokines IL-2, IL-6, and TNF-α, and upregulation of anti-inflammatory cytokine IL-10.

The invention discloses a catalytic system for efficiently synthesizing methyl cinnamate, belongs to the technical field of solid acid catalyst processing, and is used for solving the technical problem that the conversion rate of methyl cinnamate prepared by using a solid acid catalyst to catalyze a reaction between cinnamic acid and methanol and the cyclic regeneration performance of the catalytic system need to be further improved in the prior art. The preparation method specifically comprises supported solid acid and a water removal agent, and a preparation method of the supported solid acid comprises the following steps: mixing coprecipitation particles and sulfuric acid, raising the temperature of a reaction system to 70-80 DEG C, reacting for 120-160 minutes, carrying out post-treatment to obtain a supported solid acid blank, and carrying out coating modification on the supported solid acid blank through hexadecyl trimethoxysilane. According to the method, through the synergistic effect of the nitrogen-phosphorus complex and the Zr-Si skeleton and the combination of low water activity control of the 3A molecular sieve, the conversion rate of preparing methyl cinnamate through the reaction of the cinnamic acid and methanol is effectively improved, and the catalytic system also has good cyclic regeneration performance.

The invention relates to the field of gene engineering, in particular to saccharomyces cerevisiae gene engineering bacteria for producing verbascoside and echinacoside through de novo synthesis and application of the saccharomyces cerevisiae gene engineering bacteria. The genetically engineered bacterium contains a coded chorismate synthase mutant, a chorismate mutase mutant, shikimic acid kinase, cytochrome b5, glucose-6-phosphate-dehydrogenase, aromatic acetaldehyde synthase, UDP (User Datagram Protocol) glucosyltransferase, tyrosine ammonia lyase, phenylalanine ammonia lyase, cinnamate hydroxylase, 4-coumaric acid: coenzyme A ligase and acyltransferase. The invention relates to a gene encoding a UDP glucosyltransferase mutant, and more preferably, the gene encoding the UDP glucosyltransferase mutant comprises genes of a UDP glucosyltransferase mutant, a UDP glucosyltransferase mutant, a UDP glucosyltransferase mutant and a UDP glucosyltransferase mutant. Under a shake flask condition, verbascoside produced by the strain reaches 231 mg / L, echinacoside produced by the strain reaches 184 mg / L, and the strain has industrial application potential.

The invention discloses a phenolic acid or dipeptide modified nano drug delivery system for increasing oral absorption availability, which is characterized in that the system is prepared from a nano carrier and auxiliary materials, the nano carrier is modified on the surface of the nano carrier by taking phenolic acid or dipeptide as a ligand and actively targets intestinal mucosa epithelial cell surface receptors; the phenolic acid ligand is a hydroxyl cinnamic acid derivative; the dipeptide ligand is a combination of cationic amino acid and neutral amino acid. According to the invention, a nutrient substance phenolic acid or dipeptide required by a human body is creatively adopted as a ligand to construct an oral nano drug delivery system simulating a phenolic acid or dipeptide absorption pathway, and the oral absorption efficiency of the drug is remarkably improved by utilizing the natural and efficient absorption capability of small intestines to nutrient substances.

The invention relates to the technical field of biological medicines, in particular to novel application of p-hydroxycinnamic acid esterified derivatives. Research finds that an esterified derivative of p-hydroxycinnamic acid, especially methyl 4-valerylcinnamate, can effectively relieve inflammatory response of intestinal tracts and skin, protect colonic mucosal barriers and repair functional factors of intestinal barriers, so that symptoms of ulcerative colitis and atopic dermatitis are effectively relieved, the life quality of patients is improved, and the curative effect of the patients is improved. Good clinical application prospects and potential market values are realized.

The present invention relates to an agent for suppressing an unpleasant taste stemming from a high-intensity sweetener, said agent containing one or more active ingredients selected from the group consisting of lauric acid, trans-2-decenal, dodecanal, decanoic acid, anethole, nerol, tarragon essential oil, delta undecalactone, methyl cinnamate, gamma heptalactone, sweet fennel essential oil, 5-methyl-2-phenyl-2-hexenal, cassia essential oil, massoia lactone, 2-methylundecanal, thyme essential oil, trans-2-undecenal, and hedione.

The present invention relates to an off-flavor inhibitor and an off-flavor-inhibiting perfume composition for shielding off-flavor contained in foods and drinks, and foods and drinks in which off-flavor contained in foods and drinks is inhibited. The odor inhibitor of the present invention is an odor inhibitor that shields the odor contained in foods and drinks, and the odor is derived from an olfactory receptor polypeptide-responsive substance. The olfactory receptor polypeptide is at least one type selected from the group consisting of an olfactory receptor OR2AG2 and a polypeptide which contains an amino acid sequence having 80% or more identity with the amino acid sequence of the olfactory receptor and which is responsive to an odor-derived substance. The odor inhibitor contains, as a shielding component, one or more substances selected from the group consisting of isoamyl cinnamate, cinnamyl cinnamate, delta-damascone, 2, 3-heptanedione, carvacrol, Vanitol, and 5-methyl-2-phenyl-2-hexenal.

The invention belongs to the technical field of cosmetics, and provides an additive capable of increasing the sunscreen index, a sunscreen composition and application. The additive is prepared from the following components in parts by weight: 0.0001 to 1.9 parts of glucosyl hesperidin and 0.0001 to 5 parts of fructus forsythiae extract. The additive has a broad-spectrum effect of improving the sunscreen index of the sunscreen; the sun-screening agent can obviously improve the effects of physical sun-screening agents such as titanium dioxide and zinc oxide, and chemical sun-screening agents such as ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, diethylaminohydroxybenzoyl hexyl benzoate, butyl methoxydibenzoylmethane, beta-methoxycinnamate isoamyl ester, ethylhexyl salicylate and octocrylene. The additive has the sunscreen effect of mosalate and the like, or after the additive is used, the dosage is greatly reduced when the same sunscreen effect is achieved, and the problems of whitening, choking acnes, irritating sensitive skin and the like caused by too high dosage are avoided.