Use of a composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylimidazole polymer or copolymer
a technology of hydrophilic active principle and polymer or copolymer, which is applied in the field of composition comprising an oxidation-sensitive active principle, can solve the problems of easy decomposition on contact with water, conflict with desired effect, and inability to be stable in aqueous medium, and achieve good cosmetic effect, retain the depigmenting and/or lightening ability of the active principl
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Examples
example 1
[0081] Accelerated Storage Test.
[0082] The aim of this test is to study the decomposition of an oxidation-sensitive hydrophilic active principle after storing for two months at 45.degree. C. Various solutions were prepared and their compositions are collated in the following table:
1TABLE I Compositions (in Solution A water) (Control) Solution B Solution C Solution D Ascorbic acid 15% 15% 15% 15% Polymer 1 -- 1% -- --Polymer 2 -- -- 1% --Polymer 3 -- -- -- 1%
[0083] All the solutions are brought to pH 6 with 8.9 mol / l KOH.
[0084] The percentages of the polymers are given as active material.
[0085] Polymer 1: Vinylpyrrolidone / vinylimidazole (50 / 50) copolymer sold under the reference Luvitec VPI 55K72W of BASF (Weight-average molecular mass 1.2.times.10.sup.6).
[0086] Polymer 2: Vinylpyrrolidone / vinylimidazole (50 / 50) copolymer sold under the reference Luvitec VPI 55K18P of BASF (Weight-average molecular mass 10 000).
[0087] Polymer 3: Polyvinylpyrrolidone sold under the reference Kollidon ...
example 2
[0098] Demonstration of the Activity With Regard to the Dendricity of Melanocytes:
[0099] The aim of this test is to show the effect of the combination of ascorbic acid with a polymer or copolymer according to the invention on adjusting the melanogenesis of human keratinocyte-melanocyte cocultures.
[0100] Method: The cells are treated from inoculation with the ascorbic acid / vinylpyrrolidone-vinylimidazole copolymer combinations for 7 days.
[0101] Observations:
[0102] The melanocytes are labelled using the NK1beteb antibody (green colouring), which recognizes the melanosomes at every stage of maturation. The nuclei of all the cells, melanocytes and keratinocytes, are stained using propidium iodide (red colouring).
[0103] Results:
[0104] In the absence of the ascorbic acid / vinylpyrrolidone-vinylimidazole copolymer combinations, the melanocytes in cocultures are highly dendritic. The pigment is visibly transferred to the neighbouring keratinocytes.
[0105] In the presence of the ascorbic acid / ...
example 3
[0107] O / W Anti-Blemish Cream
[0108] The following composition is prepared in a way conventional to a person skilled in the art.
3 A.sub.1 Sorbitan tristearate 0.7 g Polyethylene glycol (40 EO) stearate 1.6 g Cetyl alcohol 3.2 g Glyceryl mono-, di-, tripalmitate / stearate 2.4 g Myristyl myristate 2 g Liquid fraction of karite butter 2 g Preservative 0.2 g A.sub.2 Cyclopentadimethylsiloxane 15 g B Demineralized water 60.53 g Glycerol 3 g Ascorbic acid 5 g 50% Potassium hydroxide 3.07 g Vinylpyrrolidone / vinylimidazole copolymer 1 g Preservative 0.2 g C Fragrance 0.1 g
[0109] This cream which is soft on application makes it possible to reduce pigmentary blemishes and confers good stability on ascorbic acid.
PUM
Property | Measurement | Unit |
---|---|---|
Percent by mass | aaaaa | aaaaa |
Percent by mass | aaaaa | aaaaa |
Percent by mass | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com