System for remote viewing and display of a slide

Inactive Publication Date: 2006-12-07
CARL ZEISS MICROIMAGING AIS
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However, users in the past were limited in t

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  • System for remote viewing and display of a slide
  • System for remote viewing and display of a slide

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Embodiment Construction

[0008] A virtual slide is a digital representation of an area of interest of a microscopic slide. A virtual slide can be created multiple ways.

[0009] One method is to use a motorized microscope that can move a specimen with respect to a microscope objective (e.g., a microscope with a motorized stage). With such system, one can capture one or more images through a microscope objective, such that a region of interest (all or part of the microscopic slide) is imaged. Each image is then joined together to form a composite or “virtual image.” Multiple methods of joining images together are known in the art. One example is when images are simply abutted one next to another. However, this method does not generally produce virtual slides without seams, because errors such as camera rotation relative to the axis of motion are difficult to correct. Even with submicron accuracy stages it is, in practice, difficult to obtain consistent positioning. Another method is to utilize overlap between ...

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Abstract

A method for creating a virtual slide is provided. A virtual slide is a digital representation of an area of interest of a microscope slide. One method is to use a motorized microscope that can move a specimen with respect to a microscope objective. With such a system, one can capture one or more images through a microscope objective, such that a region of interest is imaged. Each image is then joined together to form a composite or “virtual image.” In one embodiment, after a virtual slide is created, a user may fully utilize the full capabilities of the remote microscope. Among these capabilities is a set of “optical objectives” and “virtual objectives.” Optical objectives are images created by digitizing an image through a microscope objective in real time. Virtual objectives are digitally created magnifications created by utilizing the existing virtual slide data to digitally create a field of view.

Description

CROSS REFERENCE TO RELATED APPLICATIONS [0001] This is a divisional application filed from application Ser. No. 10 / 620,016, filed Jul. 14, 2003, which claims benefit of U.S. Provisional Application No. 60 / 087,523, filed Jun. 1, 1998, U.S. application Ser. No. 09 / 323,371, filed Jun. 1, 1999, and U.S. application Ser. No. 10 / 488,913, filed May 30, 2003. U.S. patent application Ser. No. 10 / 620,016 is incorporated herein by reference.BACKGROUND OF THE INVENTION [0002] This invention relates to a method and apparatus for viewing remote microscope images. [0003] Currently there is increasing demand for pathologist review of samples at remote locations. There exist multiple systems to address this need. They typically fall within one of two categories: live remote microscopy and virtual slide imaging. [0004] In live remote control microscopy, a user receives images that are taken from a slide on a microscope. In virtual slide imaging, a user receives images previously captured. Virtual sli...

Claims

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Application Information

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IPC IPC(8): G06F19/00G06K9/00G01N33/48G02BG06T9/00
CPCG06T9/007G02B21/367G16H10/40
Inventor ZEINEH, JACK A.RASHID, USMANDONG, RUI-TAO
Owner CARL ZEISS MICROIMAGING AIS
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