Reduction of the Deleterious Effects of Tobacco Smoking by the Induction of Phase 2 Enzymes by Nerf2

a technology of nerf2 and enzymes, applied in the field of tobacco treatment, can solve the problems of compensatory oxidative stress or even oxidative damage, dna damage, etc., and achieve the effect of inhibiting or reducing the deleterious effects in a human body
US20080017207A1Inactive Publication Date: 2008-01-24SAVIPU PHARMA
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
SAVIPU PHARMA
Publication Date
2008-01-24
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention features a method for inhibiting or reducing the deleterious effects of tobacco smoking including increased incidence of cancers, cardiovascular diseases, various lung disorders and the oxidative effects. The method includes the incorporation of an effective amount of a compound or a standardized plant extract that is that comprises an inhibitor of antioxidant stress due to the induction of phase 2 enzymes regulated by Nerf2 into tobacco or a tobacco product.
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Description

[0001] This application claims priority of U.S. Application Ser. No. 60 / 807,685 filed on Jul. 18, 2006 and incorporated herein in its entirety by reference.Background of the Invention

[0002] 1. Field of the Invention

[0003] The field of the invention relates to the treatment of tobacco to lessen the deleterious effect of tobacco smoking. In particular the invention relates to the treatment of tobacco or a tobacco product with an effective amount of an inhibitor of oxidative stress due to the induction of phase 2 enzymes regulated by Nerf2 such that the deleterious effects of smoking tobacco are reduced.

[0004] 2. Description of the Related Art

[0005] Tobacco smoke (TS) is a major risk factor for a number of diseases including cancer, chronic obstructive pulmonary disease (COPD) and cardiovascular disease. Smokers have a high incidence of lung cancer, which is the most common cause of cancer in Western countries, accounting for more deaths than those caused by prostrate, breast, and ...

Claims

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