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[0019]Some embodiments of the invention relate to intraluminal medical devices such as angioplasty balloon catheters and balloon-expandable stents and methods of using the same that have advantages over known such intraluminal medical devices. Specifically, some embodiments of the invention overcome or reduce the negative consequences of plaque shifting during expansion of an angioplasty balloon or stent, the “snow plow” effect, especially effects such as blocking of a branching vessel.
Problems solved by technology
Many illnesses are characterized or lead to narrowing or obstruction of the lumen of blood vessels, for example lesions such as plaque deposition, resulting in restricted flow of blood to critical parts of the body such as the heart and the brain.
Another major problem, for example as may occur during acute myocardial infarction (AMI) is that expansion of an angioplasty balloon (with or without a stent) may cause plaque or a thrombus to migrate to an undesired location, for example downstream into a narrow section of an artery, possibly obstructing blood flow and making retrieval or management of the plaque or thrombus difficult.
Method used
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embodiment 26
[0069]As shown in FIG. 5B, an embodiment 26 of an intraluminal device of the invention, comprising a catheter 28 on which is positioned a directionally-expandable angioplasty balloon 30 configured for directional expansion is guided within trunk vessel 10 along guidewire 22, until proximity with plaque lesion 24.
[0070]As shown in FIG. 5C, angioplasty balloon 30 is then directionally expanded from distal end 32 to proximal end 34.
[0071]As shown in FIG. 5D, the distal to proximal expansion of intraluminal device 26 causes plaque 24 to be pushed sideways and backwards along the inner luminal wall of trunk vessel 10, such that little if any plaque 24 is displaced towards branch vessel 12.
[0072]It should be noted that FIGS. 5A to 5D illustrate an exemplary operation in which expansion occurs in a distal to proximal direction. Similar principles apply in the case of proximal to distal, center to side and side to center directional expansions, and may be applied as required according to th...
embodiment 42
[0080]Referring now to FIGS. 7A to 7C, there is depicted an embodiment 42 of an intraluminal device of the invention comprising catheter 28 and a symmetrically-tapered angioplasty balloon 44. In balloon 44, a first end (in this embodiment, distal end 32) of a thinner material than that of a second end (in this embodiment, proximal end 34). In FIG. 7A, balloon 44 is in an uninflated state. As shown in FIG. 7B, when expansion fluid is introduced into balloon 44, less resistance to expansion is encountered at thinner end distal end 32, such that expansion is directional, from distal end 32 towards proximal end 34, until balloon 44 is fully expanded, FIG. 7C.
[0081]In some embodiments (not depicted), a stent is mounted on balloon 44 of device 42. When inflation fluid is introduced into balloon 44 causing balloon 44 to directionally expand from distal end 32 towards proximal end 34, the stent also expands directionally.
[0082]In some embodiments, a stent is crimped onto an asymmetrical or ...
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Abstract
Methods and devices useful, for example, in the field of angioplasty and stenting are disclosed. In some embodiments, the methods, devices and kits are configured for directional expansion inside a lumen, for example of a blood vessel obstructed by plaque. In some embodiments, the directional expansion displaces the plaque in a desired direction.
Description
RELATED APPLICATION[0001]The present application claims priority from U.S. Provisional Patent Application No. 61 / 092,561 filed 28 Aug. 2008.FIELD AND BACKGROUND OF THE INVENTION[0002]The present invention relates to intraluminal medical devices. In some embodiments, the invention relates to expandable devices such as angioplasty balloons and balloon-expandable stents that are configured for directional expansion, for example from a distal end of the device to a proximal end of the device or from a proximal end of the device to a distal end of the device.[0003]Many illnesses are characterized or lead to narrowing or obstruction of the lumen of blood vessels, for example lesions such as plaque deposition, resulting in restricted flow of blood to critical parts of the body such as the heart and the brain.[0004]Balloonangioplasty is a technique used to dilate a region of a lumen of a blood vessel that is narrowed or obstructed with the help of an inflatablecatheter-borne balloon. A gu...
Claims
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