Estriol therapy for autoimmune and neurodegenerative disease and disorders

US20130203722A1Inactive Publication Date: 2013-08-08RGT UNIV OF CALIFORNIA

Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
RGT UNIV OF CALIFORNIA
Publication Date
2013-08-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, including post-partum auto immune diseases) and more particularly. Most preferably the invention uses estrogens, estranges, estriol or estrogen receptor active agents to prevent or ameliorate clinical symptoms of these Th1-mediated (cell-mediated) autoimmune diseases known to either have an initial onset following the birth of a child or which are exacerbated in patients in the post-partum period.
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Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application is a continuation of U.S. patent application Ser. No. 11 / 992,558, filed Mar. 25, 2008, which claims priority from International Patent Application No. PCT / US2006 / 037259, filed Sep. 26, 2006, which claims priority to U.S. Provisional Application No. 60 / 833,527, filed Jul. 26, 2006, and U.S. Provisional Application No. 60 / 720,971, filed Sep. 26, 2005, which is a continuation-in-part application of U.S. patent application Ser. No. 11 / 151,040, filed on Jun. 13, 2005, and issued as U.S. Pat. No. 8,372,826, which is a continuation of application Ser. No. 10 / 131,834, filed on Apr. 24, 2002, and issued as U.S. Pat. No. 6,936,599, which claims priority to Provisional Application No. 60 / 286,842, filed on Apr. 25, 2001, all of which are incorporated by reference herein.

[0002] This invention was made with Government support under Grant No. NS045443 awarded by the National Institute of Neurological Disorders and Stroke, National Instit...

Claims

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