Oral Care Compositions and Methods of Use

Inactive Publication Date: 2018-11-22
COLGATE PALMOLIVE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0009]It has been surprisingly found that oral care compositions comprising hemp seed oil and caprylyl glycol show unexpected benefits within o

Problems solved by technology

Dryness of mouth is a major cause of oral stress and discomfort experienced by many individuals.
Dry mouth can lead to a parched feeling in the throat, stickiness and cotton-ness in the mouth which can make it challenging to eat, drink, or even talk.
Dry mouth can also make the throat feel sore and scratchy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

Measurement of Frictional Coefficient

[0098]The apparatus used in these studies uses a modification of a butterfly haptics Magnetic Levitation Haptic Device (MLHD) manufactured by Butterfly Haptics (Pittsburgh, Pa.) and a custom tactor (see Yardley et al., Skin Research and Technology, 2016; 22: 115-127). The MLHD is a six degree-of-freedom (6-DOF) device which uses six Lorentz actuator coils to produce rotational and linear forces on a central component known as the ‘flotor’. While in operation, the flotor of the MLHD has no physical contact with the rest of the device, and as a result there is no friction or backlash produced. The MLHD is capable of moving the flotor in a 24 mm spherical diameter with a position resolution of 2000 Hz with a resolution of 20 mN.

[0099]Since the MLHD does not come equipped with a force / torque sensor, the flotor of the MLHD was modified to accept an ATI Nano-17 6-axis force / torque sensor (ATI Industrial Automation, Apex, N.C.). The sensor was fastened ...

example 2

In Vitro Analysis of Moisture Retention Capacity

[0107]A qualitative method was developed to evaluate and demonstrate moisture retention capacity of mouthwash products. This method utilizes Vitro Skin™ (IMS Inc., Portland, Me.) as a model substrate. Vitro skin™ is an advanced testing substrate that mimics the surface properties of human skin and contains both protein and lipid components. Its topography, pH, critical surface tension and ionic strength are similar to human skin.

[0108]Briefly, 20 mm diameter Vitro skin™ sheets were punched out and placed in a six well plastic plate. 50 μl of deionized water was then added on to the Vitro skin™ surface followed by 100 μl of the mouthwash products. The liquid was mixed and spread over the Vitro skin™ surface. Samples were left at room temperature over night without the lid. After 18 hours, volunteers were asked to visually inspect the samples and rate the level of moisture present on the Vitro skin™ surface from 1 to 5, with 5 being maxi...

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Abstract

Disclosed herein are oral care compositions comprising hemp seed oil and caprylyl glycol. In certain embodiments, the oral care composition optionally further comprises one or more ingredients selected from hyaluronic acid and aloe vera. Methods of making and using the compositions are also provided.

Description

FIELD[0001]This invention relates to oral care compositions comprising hemp seed oil and caprylyl glycol. In certain embodiments, the oral care composition optionally further comprises one or more ingredients selected from hyaluronic acid and aloe vera. The invention also describes methods of making and using these compositions.BACKGROUND[0002]Dry mouth, or xerostomia, is a subjective complaint of one's mouth feeling dry. It is usually caused by a reduction in salivary flow or by changes in the biochemical composition of saliva. Dryness of mouth is a major cause of oral stress and discomfort experienced by many individuals. Epidemiologically, dryness of the mouth is one of the most prevalent oral discomforts experienced by millions of people in the United States and around the globe. In one estimate, 44 million people in the United States alone are affected by xerostomia. Although dry mouth symptoms can affect persons of any age group, dry mouth is more likely to occur in middle and...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q11/00A61K8/92A61K8/34A61K8/73
CPCA61K8/97A61Q11/00A61K8/735A61K8/345A61K8/922
Inventor ANSARI, SHAMIMTRIVEDI, HARSH MAHENDRAMASTERS, JAMES
Owner COLGATE PALMOLIVE CO
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