The present application belongs to the technical field of
cosmetics or drugs, and particularly relates to a composition for treating
gingivitis and application thereof. The composition is composed of shikonin acid and shikonin
naphthoquinone, and the
mass ratio of the shikonin acid to the shikonin
naphthoquinone is 10-100:1. The present application has excellent effects in improving gingival bleeding and inhibiting alveolar bone absorption. The shikonin acid is prepared by high-pressure
steam explosion combined with
ethanol extraction,
activated carbon decolorization and macroporous adsorption resin technology, and the shikonin
naphthoquinone is prepared by supercritical CO2 extraction combined with molecular
distillation technology. The preparation method is green, stable and controllable, the obtained
active ingredient has high purity, and is suitable for industrial production. The composition of the present application is derived from natural
plant ingredients, has high safety, can be prepared into various oral care dosage forms such as gels, toothpastes and mouthwashes, is used for the auxiliary treatment or daily care of
gingivitis, and has good application prospect.