The application discloses a
plant lactobacillus and application of the
plant lactobacillus in a composition for preventing or treating a
tic disorder, and belongs to the technical field of microorganisms. The technical problem to be solved is to provide a
plant lactobacillus LP496 isolated from healthy
breast milk, wherein the plant lactobacillus LP496 can significantly reduce a tic behavior, improve a stereotypic symptom, improve
motor coordination and repair
muscle strength damage, realize double
neurotransmitter regulation by down-regulating
dopamine and up-regulating
serotonin, and has a significant protective effect on brain
neuron damage. A technical solution point is that the plant lactobacillus LP496 has a preservation number of CGMCC No. 33499. The application further discloses a
microbial agent containing the strain or a preparation of the strain, and application of the strain and the
microbial agent in preparation of a composition for preventing or treating a
tic disorder and related compositions, and provides a safe, effective and mild new microecological intervention scheme for the
tic disorder.