8results about "Anhydrosugars" patented technology

The invention belongs to the field of separation and purification of bio-based chemicals, and particularly relates to a method for separating and purifying levoglucosenone from bio-oil. According to the method, the bio-oil obtained in the process of preparing levoglucosenone (LGO) through selective pyrolysis of biomass is used as a raw material, organic acid in the bio-oil is removed through a supersaturated carbonate solution, and then an oil phase is obtained through step-by-step extraction. And then adjusting working conditions, carrying out echelon reduced pressure distillation on the oil phase, and sequentially removing the extracting agent, low-boiling-point impurities and high-boiling-point oligomers, so as to obtain high-purity LGO. The pyrolysis bio-oil is subjected to coupling treatment of deacidification, step-by-step extraction and echelon reduced pressure distillation, so that the aim of separating and purifying high-added-value chemicals from low-value and complex-component bio-oil is fulfilled. The raw materials are cheap and easy to obtain, the process is simple, and the method is a biomass resource utilization method with great prospects.

The invention belongs to the field of separation and purification of bio-based chemicals, and particularly relates to a method for directionally separating organic acid in biomass pyrolytic oil and efficiently purifying levoglucosenone. According to the method, pyrolysis oil obtained by selective pyrolysis of biomass is taken as a raw material, firstly, a medium-polarity extraction agent is utilized to perform two-phase step-by-step fractional extraction on the pyrolysis oil, and a water phase rich in organic acid and an oil phase rich in LGO are respectively obtained; and the water phase is sequentially subjected to alkalization, acidification, filtration and water washing treatment to obtain an organic acid solid. And putting the oil phase into a rectifying tower, separating under the conditions that the temperature is # imgabs0 # and the vacuum degree is 300-2000Pa, and removing an extracting agent, furans and oligomers, thereby obtaining the high-purity LGO. The pyrolytic oil is subjected to coupling treatment of two-phase step-by-step fractional extraction, organic acid extraction and rectification, so that the aim of separating and purifying high-added-value chemicals from the low-value and complex-component pyrolytic oil is fulfilled.

The present invention provides methods of preparing immobilized engineered terminal nucleotidyl transferase (TnT) polypeptides, and compositions and methods for using these immobilized enzymes in processes for template-independent oligonucleotide synthesis.

A method for producing sugar anhydride, comprising: (1) first heat treatment step of heating polysaccharide having reducing end group at 130-350° C. in the presence of C1-C10 alcohol compound free of an acetal structure; (2) second heat treatment step of heating the first heat treated polysaccharide for pyrolysis to form a gaseous sugar anhydride, the second heat treatment forming no char or only filmy char and forming no carbon monoxide or some carbon monoxide such that the amount of carbon monoxide formed is not more than 5 parts by weight per 100 parts by weight of the absolute dry weight of the polysaccharide; and (3) recovery step of cooling the gaseous sugar anhydride to a temperature not higher than the boiling point thereof. According to this method, sugar anhydride can be easily produced at a high yield.

Compounds and compositions are described that have an asialoglycoprotein receptor (ASGPR) binding ligand conjugated to an extracellular protein binding ligand that selectively degrades target extracellular proteins in vivo to treat disorders mediated by the extracellular proteins.

To provide a polynucleotide molecule, and a polynucleotide conjugate molecule comprising a polynucleotide molecule and a linking portion.SOLUTION: A polynucleotide molecule is provided which comprises at least one 5'-vinylphosphonate-modified unnatural nucleotide, where the at least one 5'-vinylphosphonate-modified unnatural nucleotide is selected from 15 types of groups including those in the figure, where B represents a heterocyclic base moiety, and J represents an internucleotide linking group that connects the nucleotide to an adjacent nucleotide of the polynucleotide molecule.SELECTED DRAWING: Figure 1A

To provide a β(1→5)glucosylfranoside cyclic dimer and a method for producing the β(1→5)glucosylfranoside cyclic dimer.SOLUTION: The β(1→5)glucosylfranoside cyclic dimer of the present invention is represented by the following formula (1).SELECTED DRAWING: None