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Compound drop pills of dahurian rhododendron leaf and preparation method

A Manshanhong, compound technology, used in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of inaccurate dosage, low dissolution rate, low drug content, etc., and improve bioavailability. , the effect of accelerated dissolution and absorption, and a high degree of automation

Inactive Publication Date: 2008-01-30
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, the dosage form of oral liquid also has the disadvantages of low drug content, large dosage, inaccurate dosage, inconvenient taking, and inconvenient disadvantages such as going out and carrying.
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] Now with several groups of specific examples, the preparation method of the compound Manshanhong dripping pills of the present invention will be further described.

[0033] Group 1: Tests with a single matrix

[0034] 1. Preparation of drug extract:

[0035] 1.1 Prescription: Manshanhong 200g, Baibu 100g, poppy shell 50g, Campanulaceae 100g, Polygala 100g;

[0036] 1.2 Preparation method: crush the above five flavors into coarse powder, refer to the percolation method under the fluid extract and extract item on the 13th page of the Chinese Pharmacopoeia 2000 edition, use 18% ethanol as a solvent, soak for 24 hours, and use 1~ Slowly percolate at a speed of 3ml, collect the primary filtrate and store it in another container, continue percolating until there is almost no filtrate oozing out, stop percolating and combine with the primary filtrate, concentrate to a thick paste with a relative density of 1.2-1.4 to obtain the product; or It is then dried at 60°C to 80°C an...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating bronchitis, cough and asthma is prepared from 5 Chinese-medicinal materials including dahurian rhododendron leaf, stemona root, poppy capsule, platycodon root, etc.

Description

technical field [0001] The present invention relates to a kind of pharmaceutical composition which has the effects of relieving cough, eliminating phlegm and relieving asthma, and is used for treating bronchitis, cough, asthma and other diseases, especially relates to the basic formula of compound Manshan red syrup, which is formulated by formulating A kind of pharmaceutical composition oral drop pill preparation. Background technique [0002] According to the ministerial drug standard WS 3 -Compound Manshan Brown Syrup prepared according to the formula and extraction process given in B-0342-90 is a liquid that has the effects of relieving cough, eliminating phlegm and relieving asthma, and is used to treat bronchitis, cough, asthma and other diseases Oral preparations have been clinically verified and have definite curative effects. They are commonly used drugs for clinical and family treatment of such diseases. [0003] The following is the drug standard WS 3 - Formula ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/904A61K36/69A61K36/66A61K36/45A61K36/34A61P11/00A61P11/14A61P11/06A61P11/10
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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