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Stevia rebaudian valid target as well as its activity and application

A kind of technology of effective parts, stevia, applied in hypoglycemic and lipid-lowering activity and application fields

Inactive Publication Date: 2008-04-09
石任兵
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report to determine the effective part of hypoglycemic and lipid-lowering from Stevia rebaudiana

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Example 1: Preparation of stevia effective fraction capsules

[0061] Take 200g of the effective part of stevia rebaudiana, pulverize it, pass through a 80-mesh sieve, mix evenly with 100g of microcrystalline cellulose, granulate with 95% ethanol, dry, granulate with a 20-mesh sieve, and fill capsules.

Embodiment 2

[0062] Example 2: Preparation of stevia effective fraction tablet

[0063] Take 50g of the effective part of stevia rebaudiana, crush it, pass it through a 80-mesh sieve, mix it with 70g of microcrystalline cellulose and 5g of sodium carboxymethyl starch, granulate it with 5% PVP, dry it, granulate it with a 20-mesh sieve, add stearic acid Magnesium 2g, compressed into tablets.

Embodiment 3

[0064] Embodiment 3: the preparation of the effective part of Stevia rebaudiana drop pill

[0065] Take 60g of the effective part of Stevia rebaudiana, crush it, pass through a 80-mesh sieve, mix evenly, put it into 180g of heated and melted polyethylene glycol 6000, stir until dissolved, transfer it to a liquid storage bottle, seal it and keep it warm at 80-90°C, adjust Dropping pill machine liquid dosing valve, drop into the liquid paraffin at 10-15 ℃ from top to bottom, drain the formed drop pills and wipe off the liquid paraffin, and dry.

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PUM

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Abstract

The invention discloses an effective part of stevia and the activity and the application thereof. The effective part mainly comprises stevioside category and flavone category which are obtained by extracting and separating from dried stevia leaves, wherein the sum of the percentage content of the stevioside components in the stevioside part is 5 to 100 percent (w / w), and the stevioside components mainly contains the stevioside, stevibioside, rebaudioside A, B, C, D, E, and F, dulcoside A and the derivative thereof, etc.; the sum of the percentage content of the flavone components in the flavone part is 5 to 100 percent (w / w), and the flavone components mainly contains luteolin, quercetin, luteolin-7-O-Beta-D-glucoside, apigenin-7-O-Beta-D-glucoside, quercitrin, quercetin-3-O-Beta-D-arabinoside, quercetin-3-O-(4-O-anti form-caffeoyl acyl-Alpha-L-rhamnose-(1 to 6)-Beta-D-galactoside) and the derivative thereof, etc., and 4, 5-dicaffeoylquinic acid and the derivative thereof, etc. The effective part has significant sugar-reducing and fat-reducing effects, can be used singly or combined with any other Chinese medicines and Western medicines or foods in any proportion, is used for preparing medicines or functional foods, and is used for treating hyperglycemia and hyperlipoidemia.

Description

technical field [0001] The invention belongs to the technical field of food and medicine, and specifically relates to steviosides and flavonoids of effective parts of stevia rebaudiana, as well as the blood sugar and lipid-lowering activity of the effective parts and application thereof. Background technique [0002] In recent years, the problem of people's overnutrition has become more and more serious, and the voice of quitting sugar is getting higher and higher. The many harms caused by excessive consumption of sucrose have prompted scientists to constantly search for and develop new sugar sources. As a kind of natural sweetener products with high sweetness and low calorie value, stevioside and other diterpene glycoside related substances in Stevia rebaudiana leaf extract are more and more favored by consumers. It not only meets the requirements of modern dietary health, but also provides a sweet substitute that does not induce disease for patients with diabetes, obesity,...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61K9/00A61P3/10A61P3/06
Inventor 石任兵张来旺刘斌骆宾
Owner 石任兵
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