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Rotary type multichannel fluorescentinducing method based on transmission optical fiber

A technology for transmitting optical fibers and inducing fluorescence, which is applied in the field of photoelectric detection in biomedicine, and achieves the effect of high detection accuracy, fast speed, and overcoming the problems of poor positioning and repeated positioning accuracy.

Inactive Publication Date: 2010-06-09
BEIJING UNIV OF TECH
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

In this way, the two-dimensional plane movement in the X and Y directions is replaced by a rotational movement, which avoids the two-dimensional movement of the optical system. Advantages of high precision

Method used

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  • Rotary type multichannel fluorescentinducing method based on transmission optical fiber
  • Rotary type multichannel fluorescentinducing method based on transmission optical fiber
  • Rotary type multichannel fluorescentinducing method based on transmission optical fiber

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Embodiment

[0019] For such as figure 1 In the single-channel detection device shown, the light emitted by the light source 1 becomes monochromatic light through the excitation light filter 2, converges through the incident coupling lens 3, splits the light through the dichroic mirror 6, and couples into a group of multiplex transmission optical fibers 4 In one optical fiber, the monochromatic light irradiates the sample 5 in the reaction cell after coming out from the transmission optical fiber 4, and excites the sample 5 to emit fluorescence; The fluorescence from the optical fiber 4 is split by the dichroic mirror 6, and becomes parallel light through the output coupling lens 7, and the narrow-band fluorescence filtered by the release filter 8 is all projected onto a rotatable disc, and the drive motor drives the disc to rotate; A hole is opened at the place where the fluorescence is projected onto the disk, and after the projected fluorescence passes through the hole, it is vertically...

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Abstract

The invention relates to a device and belongs to the photoelectric detection field. The device sequentially comprises a light source (1), an incidence coupling lens (3), a dichroic mirror (6), transmission optical fibre (4) and an outlet coupling lens (7), and is characterized in that the transmission optical fibre (4) is a group of multichannel transmission optical fibre; the rear of the outlet coupling lens (7) comprises a releasing optical filter or a prism device (8) and a photoelectric detector (9) connected with a computer (10); The light of the light source (1) split by the dichroic mirror enters the transmission optical fibre; The fluorescence emitted by the transmission optical fibre is split by the dichroic mirror and becomes parallel light through the outlet coupling lens, and the fluorescence filtered or split by the releasing optical filter or the prism device is projected on a rotatable disk to drive a motor for driving the disk to rotate; a hole is opened in the positionwhere the fluorescence is projected on the disk, after passing through the hole, the projection light is vertically injected into the photoelectric detector to complete a channel detection; the rotation of the disk realizes a multichannel detection. The mechatronics of the invention has simple structure, fast speed and high detection precision.

Description

technical field [0001] The invention is a rotating multi-channel induced fluorescence device and method based on transmission optical fiber, which belongs to the technical field of photoelectric detection in biomedicine. Background technique [0002] Because the external light source stimulates the object to be detected to induce fluorescence detection, it has very little impact on organisms, animals and human bodies. More importantly, the dynamic range and sensitivity of fluorescence detection are getting higher and higher, approaching or catching up with radioactive detection, so fluorescence detection It is widely used in life sciences, medical research and practical applications, especially in the field of real-time detection of living organisms, animals and human bodies. [0003] In the classic multi-channel excitation-induced fluorescence device and method, one input optical fiber and another output optical fiber are used to transmit light, that is, one input optical f...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/64G01N21/01
Inventor 冯继宏曾毅耿利娜刘长波张清悦张兰
Owner BEIJING UNIV OF TECH
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