Fat taste receptors and their methods of use

A taste receptor and fat technology, used in the identification of compounds that taste like fat and in the field of food preparation, can solve the problems that the taste and delicious taste of fat cannot be completely simulated

Inactive Publication Date: 2008-07-09
NESTEC SA
View PDF0 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, some fat substitutes, while mimicking these qualities, do not quite mimic the taste and taste of fat

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Fat taste receptors and their methods of use
  • Fat taste receptors and their methods of use
  • Fat taste receptors and their methods of use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] The present invention is based in part on the discovery of fat taste receptors and the proteins that make up fat taste receptors. The protein is a member of a class of proteins known as G protein-coupled receptors, or GPCRs, and includes GPR40 and GPR120. The inventors have demonstrated that these receptors are present in cellular taste tissue expressing Trpm5, a key taste signaling protein. In addition, the inventors demonstrated that mice lacking a functional GPR40 gene (GPR40 knockout mice) had a decreased preference for and intake of corn oil, Intralipid, lauric acid, and oleic acid. Together, these data demonstrate that GPR120 and GPR40 are fat taste receptors and can be utilized as screening tools for compounds that mimic fat taste. Such compounds can be incorporated into foods as fat substitutes.

[0020] Fat taste receptor proteins were identified in part by analogy to the taste phenomenon of bitter, sweet, and umami compounds in which taste perception is elic...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

Fat taste receptors and methods for using the receptors to screen compounds that mimic fat taste are disclosed. The receptors can include G-protein coupled receptor proteins, such as GPR40 or GPR120. New methods for preparing foods are also disclosed that involve testing compounds in the assay system and then incorporating into foods the identified nonfat compounds that have the taste of fat.

Description

Background of the invention [0001] The mouth's detection of fat has traditionally been thought to depend on its texture, viscosity and smell. However, some fat substitutes, while mimicking these qualities, do not quite mimic the mouthfeel and delicious taste of fat. [0002] Partly for this reason, a fatty taste is believed to be present. fMRI (functional magnetic resonance imaging) studies have shown that vegetable oils stimulate the gustatory areas of the human cortex, and neural recordings in rats have shown that application of free fatty acids (FFA) to the tongue stimulates the lingual branch of the glossopharyngeal nerve. This suggests that fat sensation has an outer trifurcated component. Isolated rat taste cells have also been observed to inhibit delayed rectifier potassium channels in response to medium- and long-chain FFAs. Thus, several lines of evidence suggest that medium- and long-chain FFAs are capable of eliciting a fatty taste. [0003] The food industry ur...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C07K14/72G01N33/04
CPCC07K14/705A23L35/00A23V2200/14C07K14/723G01N33/566
Inventor S·达马克J·勒-库特C·贝岑农C·卡尔托尼
Owner NESTEC SA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap