Green prune extract of anti acquired immuno-deficiency syndrome and bacterium

An anti-AIDS and extract technology, applied in the field of biomedicine, can solve the problems of no antibacterial reports, etc., achieve significant anti-AIDS virus and antibacterial effects, wide source of raw materials, and remarkable effects

Inactive Publication Date: 2008-09-03
陈光英 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After a comprehensive search of domestic and foreign literature, there is no report on its chemic

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Dry the greengage and crush it into powder, extract the greengage powder with 70% ethanol under reflux, combine the extracts, filter, recover the ethanol under reduced pressure, dilute with water, extract with ethyl acetate, concentrate the extract to obtain an extract, vacuum Drying to obtain powder is green plum extract.

Embodiment 2

[0018] Dry the greengage and crush it into powder, extract the greengage powder with 90% ethanol under reflux, combine the extracts, filter, recover the ethanol under reduced pressure, dilute with water, extract with ethyl acetate, concentrate the extract to obtain an extract, vacuum Drying to obtain powder is green plum extract.

Embodiment 3

[0020] Dry the greengage and crush it into powder, extract the greengage powder with 70% methanol under reflux, combine the extracts, filter, recover the ethanol under reduced pressure, dilute with water, extract with ethyl acetate, concentrate the extract to obtain an extract, vacuum Drying to obtain powder is green plum extract.

[0021] Examples of anti-HIV virus activity using green plum extract:

[0022] The sample to be tested was dissolved in RPMI-1640 complete medium and sterilized by 0.22 μm filter membrane, stored at 4°C, and the storage concentration was 1.0 mg / ml; AZT was dissolved in RPMI-1640 complete medium and 0.22 μm filter membrane was sterilized. Store at -20°C after aliquoting. All cells and viruses were cultured in RPMI-1640 complete medium containing 10% calf serum. Prepare HIV-1 by conventional method IIIB , titrate and calculate the TCID of the virus 50 . After aliquoting the virus stock solution, store it at -70°C. Cells and viruses were frozen a...

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PUM

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Abstract

The invention relates to the application of a prunus mume extract, and belongs to the field of biomedicines. The extract is obtained by extracting prunus mume with organic solvent, performing liquid extraction with organic solvent, and optionally refining; and can be used for preparing anti-HIV and antibacterial drugs. The inventive drugs have the advantages of high bioavailability of plant, good therapeutic effect, easily accessible raw material, and good safety. Researches and developments on the pharmacological activity of the extract are of great significance, and the extract has wide application prospect.

Description

technical field [0001] The invention relates to biomedicine, in particular to a plum extract used for anti-AIDS virus and antibacterial. Background technique [0002] The disease caused by HIV infection is called AIDS, and its full name is acquired immunodeficiency syndrome (acquired immunodeficiency syndrome, AIDS). + The number of cells decreases, followed by opportunistic infections, tumors, etc., and the clinical manifestations are various. The disease spreads quickly, has a high fatality rate, and is currently incurable, which has attracted the attention of governments and societies in various countries. [0003] Two types of HIV have been identified, namely HIV-1 and HIV-2. Both have similar viral structures and transmission routes. HIV-2 is mainly distributed in West Africa and has also been detected in some infected people in Europe and the Americas. Its virulence and transmissibility are lower than that of HIV-1, and the course of AIDS caused by it is slower and...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P31/04A61P31/18A61K125/00
Inventor 陈光英宋小平舒火明陈忠韩长日莫峥嵘
Owner 陈光英
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