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Film coating agent for treating skin ulcer

A technology for skin ulcers and coating agents, which is applied in the direction of skin diseases, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve airtight, easy-to-contaminate wounds, and inability to absorb wound exudate, etc. question

Inactive Publication Date: 2008-09-17
乔晋琳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the former method can achieve anti-inflammatory and analgesic effects, since the base of the anti-inflammatory ointment is mainly vaseline, the wound is airtight after the ointment is applied, and the wound exudate cannot be absorbed, so it is not conducive to the repair of the wound.
With the latter method, the wound is ventilated, but it is easy to contaminate the wound and has no analgesic effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] 100 grams of notoginseng, 100 grams of broken blood flow, 100 grams of centella asiatica, 8 grams of borneol, and 0.5 grams of artificial musk.

Embodiment 2

[0014] Sanqi 130g, Duanxueliu 140g, Centella asiatica 180g, Borneol 18g, Artificial musk 1g.

[0015] The optimal ratio is: Panax notoginseng 120 grams, Duanxueliu 120 grams, Centella asiatica 160 grams, borneol 16 grams, artificial musk 0.8 grams.

[0016] Wherein, the above-mentioned gel matrix is ​​mainly made of polyvinyl alcohol, and then compounded with carboxymethyl cellulose sodium. The above-mentioned polyvinyl alcohol can adopt medical polyvinyl alcohol, such as polyvinyl alcohol-124.

[0017] Preparation method: Take 120 grams of Panax notoginseng, 120 grams of Duanxueliu and 160 grams of Centella asiatica, add 6 times of water to soak for 1 hour, decoct twice, 1 hour each time, combine the decoctions, and concentrate under normal pressure to Each milliliter contains 1 gram of crude drug, refrigerated, left to stand for 24 hours, and filtered to obtain a clear liquid; another 0.8 gram of artificial musk and 30 milliliters of glycerin is ground for later use, borneo...

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PUM

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Abstract

The invention discloses a coating agent treating skin ulcer aiming at solving the problems such as poor antalgic effect and air permeability for prior art. The coating agent treating skin ulcer is produced by following drugs with weight through matching gel-type vehicle with formula dosage according to conventional process: notoginseng 120g, clinopodium herb 120g, asiatic centella 160g, borneo l16g and artificial musk 0.8. The coating agent treating skin ulcer has the advantages of inhibiting platelet aggregation, dilating micro-vessel of partial ulcer, preventing micro thrombus from being formed and antagonizing forming inflammatory mediators, greatly improving partial blood supply of the ulcer, lowering pH value of ulcer surface, promoting acidic environment and facilitating repairing the ulcer and obviously shortening ulcer healing time.

Description

technical field [0001] The invention relates to a coating agent for treating skin ulcers. Background technique [0002] Chronic skin ulcer (CSU), also known as refractory ulcer, has complicated etiology. Common causes include: trauma, infection, vascular disease, chronic compression (decubitus), burns, etc. The local ischemia and hypoxia of ulcer is its common pathophysiological feature. Because of its protracted and difficult to heal, and easy to relapse, it has been paid attention by clinicians. Under the current conditions, anti-inflammatory analgesic ointment or sterile gauze is usually applied after debridement for cleaning. Although the former method can achieve anti-inflammatory and analgesic effects, since the base of the anti-inflammatory ointment is mainly vaseline, the wound surface is airtight after the ointment is applied, and the wound exudate cannot be absorbed, so it is not conducive to the repair of the wound surface. The latter method can ventilate the ...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K47/38A61P17/02A61K31/045A61K35/55
Inventor 乔晋琳
Owner 乔晋琳
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