Emulsifiable paste for curing acne and preparation thereof

A technology of cream and acne, applied in the field of medicine for treating acne and its preparation, which can solve the problems of short drug action time, dry skin, peeling, etc., and achieve the effect of strong antibacterial effect, delicate paste, and increased water absorption

Inactive Publication Date: 2008-11-05
哈尔滨乐泰生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention aims to solve the defects of dry skin after use, even peeling and cracking, and short drug action time in existing medicines for treating acne, and provides a cream for treating acne and a preparation method thereof

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0007] Specific embodiment 1: The cream for treating acne of this embodiment consists of 7-13 parts of clindamycin hydrochloride, 5.6-10.4 parts of metronidazole, 59.5-110.5 parts of stearic acid, and 42-78 parts by weight. It is made of glyceryl monostearate, 84-156 parts of white petrolatum, 21-39 parts of polysorbate 80, 35-65 parts of glycerin and 445.9-828.1 parts of water.

specific Embodiment approach 2

[0008] Embodiment 2: The cream for treating acne in this embodiment consists of 8 to 12 parts of clindamycin hydrochloride, 6.4 to 9.6 parts of metronidazole, 68 to 102 parts of stearic acid, and 48 to 72 parts by weight. Glyceryl monostearate, 96-144 parts of white petrolatum, 24-36 parts of polysorbate 80, 40-60 parts of glycerin and 509.6-764.4 parts of water.

specific Embodiment approach 3

[0009] Specific embodiment three: The cream for treating acne of this embodiment consists of 8.5 to 11.5 parts of clindamycin hydrochloride, 6.8 to 9.2 parts of metronidazole, 72.25 to 97.75 parts of stearic acid, and 51 to 69 parts by weight. Glyceryl monostearate, 102-138 parts of white petrolatum, 25.5-34.5 parts of polysorbate 80, 42.5-57.5 parts of glycerin and 541.45-732.55 parts of water.

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PUM

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Abstract

The invention discloses a cream for treatment for acnes and a preparation method thereof, which relates to a drug for the treatment for acnes and the preparation method thereof. The invention can solve the shortcomings that the existing drugs for the treatment for acnes can cause dry skin after usage, even peeling, cracking and short action time of the drug. The cream for the treatment for acnes of the invention is prepared by clindamycin hydrochloride, metronidazole, stearic acid, glycerol monostearate, white Vaseline, polysorbate 80, glycerin and water; the preparation method is carried out according to the following steps: (1) the oil phase is prepared; (2) the water phase is prepared; and (3) the oil phase is added into the water phase; thus obtaining the cream for treatment for acnes. The cream for treatment for acnes can kill propionibacterium acnes, have long action time of the drug and have no peeling and cracking phenomena after the usage.

Description

Technical field [0001] The invention relates to a medicine for treating acne and a preparation method thereof. Background technique [0002] Acne is a chronic inflammation of the sebaceous glands of the hair follicle. It is generally caused by sebum in the hair follicle. The sebum in the hair follicle leads to the proliferation of Propionibacterium acnes in the hair follicle. The enzyme produced by Propionibacterium acnes can decompose sebum to produce free fatty acids. The hair follicles produce irritation and cause inflammation. Existing acne treatment drugs have the defects of dry skin, even peeling and cracking after use, and short action time of the drugs. Summary of the invention [0003] The invention aims to solve the defects of dry skin, even peeling, cracking, and short drug action time in the existing medicine for treating acne after use, and provides a cream for treating acne and a preparation method thereof. [0004] The acne treatment cream of the present invention...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7056A61K9/06A61K47/34A61P17/10A61P31/02A61K31/4164A61K47/26
Inventor 郎伟君
Owner 哈尔滨乐泰生物科技有限公司
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