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Compound Tripterygium wilfordii multi-glycosides formulation for curing rheumatic disease and preparation method thereof

A technology of tripterygium glycosides and rheumatic diseases, which is applied in the field of compound tripterygium polyglycosides preparations and its preparation, and can solve problems such as high toxicity and gastrointestinal damage

Inactive Publication Date: 2008-11-05
JIANGXI HERBFINE HI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the unilateral preparation of Tripterygium wilfordii is very toxic, and long-term use will cause great damage to the heart, liver, kidney, hematopoietic system, and gastrointestinal tract.

Method used

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  • Compound Tripterygium wilfordii multi-glycosides formulation for curing rheumatic disease and preparation method thereof
  • Compound Tripterygium wilfordii multi-glycosides formulation for curing rheumatic disease and preparation method thereof
  • Compound Tripterygium wilfordii multi-glycosides formulation for curing rheumatic disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Example 1 A compound tripterygium glycoside preparation for treating rheumatic diseases, which is a preparation made from tripterygium glycosides and artemether.

Embodiment 2

[0058] Example 2 A compound tripterygium glycosides preparation for treating rheumatic diseases, its weight ratio is: 5 grams of tripterygium glycosides; artemether: 5-30 grams.

Embodiment 3

[0059] Example 3 A compound tripterygium glycosides preparation for treating rheumatic diseases, the weight ratio of which is: 5 grams of tripterygium glycosides; artemether: 20-30 grams.

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PUM

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Abstract

The invention relates to a compound tripterygium glycoside preparation for treatment for rheumatic diseases and a preparation method thereof. The invention takes tripterygium glycoside and artemether as main drugs and is in combination with pharmaceutical excipients, microcrystalline cellulose, lactose, low-substituted hydroxyproxyl cellulose, tiny powder silica gel and magnesium stearate for preparing tablets. The weight ratio is that: 5g of tripterygium glycoside and 5 to 30g of artemether. The invention proposes to allow the tripterygium glycoside and the artemether to be compatible to realize the synergy of the efficacies, and the compatibility of the tripterygium glycoside and the artemether has higher treatment effects on rheumatic diseases than that of the tripterygium glycoside.

Description

technical field [0001] The invention relates to a preparation for treating rheumatic diseases and a preparation method thereof. In particular, a compound tripterygium glycoside preparation containing tripterygium glycosides and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disease, because the abnormality of immune cells causes synovial inflammation and hyperplasia, accompanied by a large number of inflammatory factors, thus causing bone and joint damage irreversible damage. Clinical subjective symptoms include limb joint pain and morning stiffness, and pathological examination shows the destruction of joint bone. [0003] RA is a common disease that can occur in people of all age groups, and the incidence rate increases with age. According to the survey, there are about 400 million patients with rheumatism in the world, which is the largest type of disease in the medical field. In Ch...

Claims

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Application Information

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IPC IPC(8): A61K36/37A61K9/20A61P19/02A61P29/00A61K31/357
Inventor 饶毅吕爱平魏惠珍罗晓健龚建平陈兰英陈银芳王金钱方海红张洁易剑峰彭旻
Owner JIANGXI HERBFINE HI TECH
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