Glue for wound hemostasis and healing and preparation method thereof
A wound and process technology, applied in the field of wound hemostatic healing glue and its preparation, can solve the problems of poor hemostatic effect, wound susceptibility to infection, and high requirements for blood storage, so as to reduce bleeding of the wounded, reduce medical costs, and reduce relapses. Effect of infection
Inactive Publication Date: 2009-01-21
方薛行
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Problems solved by technology
At present, dressing materials such as gauze are generally used to treat wounds and stop bleeding in different occasions such as hospitals. We know that gauze and other medical dressing materials do not have a good hemostatic effect, and the wounded may still bleed continuously after bandaging. If there is too much bleeding If there are too many seriously injured, a large amount of blood will be needed, which may cause an emergency situation where plasma is not enough, and some blood types are rare and it is difficult to find a suitable blood type. At the same time, the storage of blood The requirements are high, and the cost of storage is also high, and gauze and other medical dressing materials are easy to infect the wound and cause environmental pollution after use
Method used
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[0022] The present invention is a wound hemostatic and healing gel, comprising the following raw materials:
[0023] 1), Methanol (CH3OH), generally use industrial methanol;
[0024] 2) For paraformaldehyde (CH2O), industrial paraformaldehyde products with a content ≥ 90.0% can be used;
[0025] 3), catalyzer, adopts hexahydropyridine (C5H111N) as basic catalyst in the present embodiment, it generally adopts industrial hexahydropyridine products to get final product; Described catalyst can be sodium hydroxide, potassium hydroxide, pyridine Anchorage (such as hexahydropyridine), ethanolamine (such as diethanolamine), triethylamine, etc.
[0026] 4) Ethyl cyanoacetate (NCCH2COOC2H5), generally adopts industrial ethyl cyanoacetate products with content ≥ 99.0 and acidity (acetic acid) ≤ 0.02%. It is colorless or light yellow liquid in appearance;
[0027] The ethyl cyanoacetate compound can be but not limited to ethoxyethyl cyanoacetate, can also be 2-octyl cyanoacetate, methox...
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Abstract
The invention relates to a wound hemostatic healing adhesive and a preparation method thereof, and the adhesive contains the following ingredients of methyl alcohol, paraformaldehyde, catalyst, ethyl cyanoacetate, plasticizer, dehydrating agent, stabilizing agent, depolymerizing agent, polymerization inhibitor, sulfur dioxide and acetone, and the weight ratio of the ingredients is 1 to 3: 0.5 to 1.5: 0.001 to 0.004: 2 to 3: 0.1 to 0.3: 2 to 6:0.05 to 0.15: 0.02 to 0.1: 0.02 to 0.1: 20 to 80PPM: 0.5 to 2. The healing adhesive has the effects of safety, environmental protection and rapid wound hemostasis and healing. In preparation, the method has six steps of polycondensation, dealcoholization, dehydration, depolymerization, rectification and adhesive mixture.
Description
【Technical field】 [0001] The invention relates to a medicine for hemostasis and healing of wounds and a preparation method thereof. 【Background technique】 [0002] We are easily injured if we are not careful in our daily life. In various accidents such as earthquakes, natural disasters, wars, traffic safety, accidents, etc., it is more likely to cause a large number of injuries to people and animals, ranging from small scars, wounds and a small amount of bleeding If the incident is serious, it will cause a large wound and a large amount of bleeding. At this time, it is necessary to bandage the wound and stop the bleeding as soon as possible. At present, dressing materials such as gauze are generally used to treat wounds and stop bleeding in different occasions such as hospitals. We know that gauze and other medical dressing materials do not have a good hemostatic effect, and the wounded may still bleed continuously after bandaging. If there is too much bleeding If there are...
Claims
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IPC IPC(8): A61L15/24A61L15/58A61L15/42
Inventor 方薛行
Owner 方薛行