Bee pollen peptide slice and preparation method thereof

A technology of bee pollen and peptide tablets, applied in the biological field, can solve the problems of less dissolution of active ingredients, low absorption and utilization rate, allergy phenomenon, etc., and achieve the effect of enriching species and eliminating fatigue.

Inactive Publication Date: 2011-10-05
徐春华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no effective development and utilization at present, direct consumption or ingestion, the dissolution of active ingredients is very small, the absorption and utilization rate of the human body is very low, and some people will also have allergies

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The preparation method of this bee pollen peptide tablet is to crush the bee pollen after screening, removing impurities and drying, the particle size reaches 40-80 mesh, add process water with 40% bee pollen weight, stir evenly, and place it below -18°C Freeze for 24-48 hours. Immediately after taking it out, add 100°C bee pollen weight 160% process water and stir to dissolve, use a homogenizer to homogenize for 20-60 minutes, put it into an enzymatic hydrolysis tank and add cellulase for enzymatic hydrolysis for 0.5-2 hours, and then use lye After adjusting the pH value, add neutral protease for enzymatic hydrolysis for 3-6 hours. Immediately after enzymolysis, heat the bee pollen peptide solution to 80°C and keep it warm for 30 minutes to inactivate the enzyme. Using starch as excipient, granulate in a boiling one-step granulator. Control the water content of the granules below 5%, then add magnesium stearate, polyvinylpyrrolidone and other auxiliary materials into...

Embodiment 2

[0023] The preparation method of this bee pollen peptide tablet is to crush the bee pollen after screening, removing impurities and drying, the particle size reaches 40-80 mesh, add process water with 40% bee pollen weight, stir evenly, and place it below -18°C Freeze for 24-48 hours. Immediately after taking it out, add 100°C bee pollen weight 160% process water, stir and dissolve, use a homogenizer to homogenize for 20-60 minutes, adjust the pH value with lye, and then add complex protease for enzymatic hydrolysis for 3-6 hours. Immediately after enzymolysis, heat the bee pollen peptide solution to 80°C and keep it warm for 30 minutes to inactivate the enzyme. Using starch as excipient, granulate in a boiling one-step granulator. Control the water content of the granules below 5%, then add magnesium stearate, polyvinylpyrrolidone and other auxiliary materials into the mixer for mixing, and then compress the granules in the tablet machine for sampling, according to Q / DLY018-...

Embodiment 3

[0025] The preparation method of this bee pollen peptide tablet is to crush the bee pollen after screening, removing impurities and drying, the particle size reaches 40-80 mesh, add process water with 40% bee pollen weight, stir evenly, and place it below -18°C Freeze for 24-48 hours. Immediately after taking it out, add 100°C bee pollen weight 160% process water and stir to dissolve, use a homogenizer to homogenize for 20-60 minutes, put it into an enzymatic hydrolysis tank and add cellulase for enzymatic hydrolysis for 0.5-2 hours, and then use lye After adjusting the pH value, add compound flavor protease for enzymolysis for 3-6 hours. Immediately after enzymolysis, heat the bee pollen peptide solution to 80°C and keep it warm for 30 minutes to inactivate the enzyme. Using starch as excipient, granulate in a boiling one-step granulator. Control the water content of the granules below 5%, then add magnesium stearate, polyvinylpyrrolidone and other auxiliary materials into ...

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Abstract

The invention belongs to the biological technical field, which relates to a tablet which is produced by the performing enzymolysis on bee pollen by protease to obtain a polypeptide, and producing the polypeptide into the tablet and a method for preparing the same. The bee pollen after screening, impurity removal and drying is crushed until the requirement is met, added with fresh water and evenlystirred and frozen at a temperature below 18 DEG C below zero for 24 to 48 hours; the mixture is taken out, added with fresh water with the temperature of 100 DEG C and stirred until the mixture is dissolved; the mixture is homogenized by a homogenizer for 20 to 60 minutes, put in an enzymolysis container and added with cellulase for enzymolysis for 0.5 to 5 hours, and the pH value of the mixtureis adjusted by alkali liquor and added with the protease for enzymolysis for 3 to 6 hours; after enzymolysis, the bee pollen peptide liquid is heated up for killing enzyme; by taking starch as an excipient, the granulation is performed; the water content of the granule is controlled to below 5 percent, and the granules are put in a mixer, and evenly mixed with auxiliary materials such as magnesium stearate, polyvinylpyrrolidone and the like, and the granules are put in a tablet machine for tabletting; by the sampling analysis of acid soluble proteins, microbes and nutrient components, the results meet the requirements; and finally, the obtained tablets are bottled to obtain finished products.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a tablet made from bee pollen enzymatically hydrolyzed into polypeptide by protease and a preparation method thereof. [0002] The raw material bee pollen used in this product comes from the primeval forest of Daxing'an Mountains. It is located between 50 degrees and 53 degrees north latitude. It is a natural pure land with a large temperature difference between day and night, which is suitable for the growth of wild flowers. The vegetation here is lush and rich in species. On the 84,000 square kilometers of land, there are thousands of wild plants, including 59,850 mu of honey, powder, and glue source plants, and the annual reserves of bee products can reach 840,000 tons. The raw materials of this product are all in line with the organic food production and processing standards of the EU organic food certification organization, and it is a safe functional nutritional foo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K35/64A61P3/02C12P21/00A61K38/00
Inventor 徐春华
Owner 徐春华
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