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Medicament capable of protecting cell membrane

A technology of drugs and medicinal ingredients, applied in the field of drugs that reduce the damage of free radicals to cell membranes, and can solve problems such as illegality and inconvenient injections

Inactive Publication Date: 2009-10-21
BEIJING COMPETITOR SPORTS SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, in fact, sports teams do use fructose 1,6-bisphosphate, and often adopt intravenous injection, but the inconvenience and illegality of injection are self-evident

Method used

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  • Medicament capable of protecting cell membrane
  • Medicament capable of protecting cell membrane
  • Medicament capable of protecting cell membrane

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Get each component as follows (weight in g): 1,6-diphosphate fructose 35, taurine 14, L-aspartic acid 5.3, vitamin B 1 1. Citric acid 1.1, sieve the above ingredients according to the proportion from small to large (40 mesh), remove the impurities in the residue on the sieve, and sieve the large particles after pulverizing with a pulverizer; then put the weight ratio close to The materials are mixed one by one in the order from small to large in proportion, fully stirred, poured into the capsule filling mold to make capsules, planed the powder on the surface of the capsules, and packed in medicine bottles. Add desiccant and cotton into the medicine bottle, then seal the electromagnetic induction membrane, screw the cap, and sterilize to obtain the 1,6-diphosphate fructose capsule preparation of the present invention that protects the cell membrane and reduces free radical damage to the cell membrane.

Embodiment 2

[0026] Get the following ingredients (weight in g): 1,6-diphosphate fructose 40, taurine 14, L-aspartic acid 4, vitamin B 1 1. Citric acid 1, starch 20, dextrin 20, sucrose powder 20, sieve the above ingredients from small to large (40 mesh), remove impurities in the residue on the sieve, and grind the large particles with a pulverizer before passing screen. Then mix the materials with similar weight ratios one by one in the order of proportion from small to large, stir well, use 80% ethanol as a binder, and make a suitable soft material, pass the above soft material through the YK with 12 mesh -160 type oscillating granulator to make wet granules; divide the wet granules evenly, and after the alcohol is completely volatilized, put the bulk material into the DPL-30 multifunctional granulator, and boil and dry at 50°C for one hour , so that the water content of the final product is controlled within 5%; then the granules are sized and subpackaged to obtain the 1,6-diphosphate ...

Embodiment 3

[0028] Get each component as follows (weight in g): 1,6-diphosphate fructose 30, taurine 12, L-aspartic acid 6, vitamin B 1 2, citric acid 2, starch 5, dextrin 7, above each batching is sieved (40 order) from small to large successively, the impurity in the residue on the sieve is removed, and big particle is sieved after pulverizing with pulverizer. Then mix the materials with close weight ratios one by one in order of proportion from small to large, stir well, add 1% of the total weight of the above materials HPMC and 1.5% CMS-Na, mix all the above materials, add 60% The ethanol aqueous solution is fully stirred to make soft materials; the above soft materials are granulated through a YK-160 swing granulator with 12 mesh meshes to make wet granules; Batch materials are put into a DPL-30 multifunctional granulator, boiled and dried at 60°C to make dry granules; an appropriate amount of magnesium stearate is added to the granules, and they are compressed into tablets by a tabl...

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Abstract

The invention relates to a medicament capable of protecting a cell membrane, comprising main components of fructose-1,6-diphosphate or salts thereof, taurine, L-asparaginic acid or salts thereof, citric acid and vitamin. The medicament can protect the cell membrane, reduce the damage of free radicals to the cell membrane, quickly provide a large amount of energy substances, quickly repair damaged muscle, promote aerobic metabolism and avoid corresponding lactic acid accumulation. The animal experiment proves that the medicament can markedly improve and train the swimming capability of wistars and can prevent skeletal muscle contraction device from being damaged by sports. The medicament provided by the invention is convenient to use, and particularly suitable to athletes practicing endurance events.

Description

technical field [0001] The invention relates to a medicament, in particular to a medicament capable of protecting cell membranes and reducing the damage of free radicals to the cell membranes. Background technique [0002] During intense physical activity, the consumption of oxygen increases significantly, making the body in a state of relative hypoxia. At the same time, the consumption of antioxidant substances (vitamin C, vitamin E, mercapto) in the body also increases accordingly. The effects of these two aspects As a result, a large number of free radicals can be produced in the body, and these free radicals will invade the cell membranes of all tissues in the human body, causing lipid peroxidation on the cell membranes, and the lipid peroxidation damage of the tissue cell membranes is manifested as early fatigue in the body of sports people , It is difficult to recover after fatigue, thereby reducing exercise capacity. In addition, due to various reasons, sports people...

Claims

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Application Information

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IPC IPC(8): A61K31/7024A61K31/185A61K31/51A61P39/06A61P43/00
Inventor 白厚增杨则宜焦颖
Owner BEIJING COMPETITOR SPORTS SCI & TECH
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