Application of ergot sterone in preparation of diuresis medicine

Abstract

The invention relates to an application of ergot sterone in preparation of diuresis medicine. Polyporus umbellatus crude drug is mainly used for clearing damp and promoting diuresis and treating dysuria, edema, diarrhea, strangury with turbid urine and morbid leucorrhea. The inventor utilizes diuresis as pharmacological index and screens target area and active ingredients identical with the function of the polyporus umbellatus on the basis of chemical ingredient research on the polyporus umbellatus. Normal saline loaded water retention animal model is adopted for diuresis screening on sterides compound therein, and the ergot sterone is found to have better diuresis effect and is determined as the target area of diuresis of the polyporus umbellatus.

Description

technical field

[0001] The invention relates to the application of ergosterone in the preparation of diuretic drugs, belonging to the technical field of medicine. Background technique

[0002] Polyporus umbellatus (Pers.) Fries] is a Polyporaceae plant. Its dry sclerotium is called medicinal Polyporus umbellatus, which is a commonly used traditional Chinese medicine. It is distributed in the Americas and is also used medicinally. Polyporus has a medicinal history of more than 2,500 years in China. It was first recorded in "Shen Nong's Materia Medica", and it was recorded in later "Chinese Materia Medica" and "Treatise on Febrile Diseases". For the "Chinese Pharmacopoeia" included. It has diuretic, anticancer and antibacterial effects, and its main function is diuresis and dampness. Many diuretic compound preparations contain Polyporus, such as Zhuling Decoction, Zhuling Pill, Zhuling Powder, Wuling Powder, Fenxiao Decoction, Yinchen Wuling Powder, etc. These compounds hav...

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