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Medical cassava starch composite film and preparation method thereof

A technology of tapioca starch and production methods, applied in medical science, absorbent pads, bandages, etc., can solve the problems of rare medical applications, and achieve the effects of good biocompatibility, good development prospects, and high wet strength

Inactive Publication Date: 2010-02-10
TROPICAL CORP STRAIN RESOURCE INST CHINESE ACAD OF TROPICAL AGRI SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the domestic research on starch and polyvinyl alcohol film is mainly in plastics and food, and the research on medical application is rare.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] 1. Gelatinization of starch

[0019] Weigh 6g starch, add 50ml distilled water, heat and stir in a water bath at 80℃, and gelatinize for 30min

[0020] 2. The dissolution of polyvinyl alcohol

[0021] Control the temperature of the water bath to 95°C, add 3g of polyvinyl alcohol to 100ml of distilled water to soak, wait for the water temperature to reach 95°C, put it in the water bath, stir for half an hour, and pass through a 250 mesh sieve after dissolution.

[0022] 3. Mix the solution and spread the film

[0023] Dissolve 0.2 g of sodium trimetaphosphate and 0.2 g of boric acid in 10 ml of distilled water to prepare a solution, add the polyvinyl alcohol solution to the gelatinized starch paste, and add the crosslinking agent solution at the same time. After stirring at 80°C for 10 minutes, take out the water bath and let it stand for 10 minutes, spread the film on the glass plate, and dry it in an oven at 50°C to form a film.

[0024] 4. Cross-linking

[0025] The film was cro...

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PUM

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Abstract

The invention belongs to the field of pharmaceutical material and particularly relates to a medical cassava starch composite film prepared by the compounding of cassava starch and a preparation methodthereof; and the preparation method comprises the following steps: simultaneously weighting cassava starch, polyvinyl alcohol and crosslinking agent according to a certain proportion, then dissolvingseparately, mixing the raw materials, spreading film, crosslinking, removing impurities and loading drugs to prepare the medical cassava starch composite film. The composite film of the invention haswide sources of raw materials and cheap price; cassava starch and polyvinyl alcohol are crosslinked to prepare the reinforced and toughened starch composite film so that the composite film has good biocompatibility, drug-loading property and degradability and higher wet strength; and the film can be used for the coating of body surface traumas, burns and the like and the used waste material can be fairly rapidly degraded so that the medical cassava starch composite film can be utilized to develop a kind of environmentally protective medical film material and has better development potential.

Description

Technical field [0001] The invention relates to a medical polymer film, in particular to a medical tapioca starch composite film prepared by using tapioca starch and a preparation method thereof, belonging to the field of medical materials. Background technique [0002] Polymer membranes, especially natural polymer membranes, are increasingly widely used in the medical field and are making major contributions to human health and longevity. Bioabsorbable medical films have good application prospects in abdominal surgery and external trauma. The main polymer film materials currently used in medical treatment include polylactic acid, cellulose, cellulose acetate, acrylic polymer, polyester, polycarbonate, polyolefin, etc., among which polylactic acid polymer film materials are The performance indicators are good, but most of the products need to be imported from abroad, the price is more expensive, and the long-term dependence on imports has seriously restricted the development of m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/24A61L15/18A61L15/44
Inventor 张可喜曹阳李开绵蒋盛军曹献英王江叶剑秋赵同建王华明李鸿
Owner TROPICAL CORP STRAIN RESOURCE INST CHINESE ACAD OF TROPICAL AGRI SCI
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