Honghuoma extract and its preparation method and application

A technology of red live hemp and extract, which is applied in the field of Chinese herbal extracts and traditional Chinese medicine, and can solve the problem of no more effective therapeutic drugs

Inactive Publication Date: 2010-03-24
HUAZHONG UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] For autoimmune diseases, there are currently no more effective therapeutic drugs at home and abroad except for glucocorticoids and highly toxic immunosuppressive drugs such as CsA and FK506.

Method used

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  • Honghuoma extract and its preparation method and application
  • Honghuoma extract and its preparation method and application
  • Honghuoma extract and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] The preparation of the red live hemp extract of the present invention

[0074] Take 6kg of red live hemp produced in Enshi, Hubei, dry the medicinal materials, cut them into pieces, soak them in 95% medical alcohol to make them submerged, soak for three days each time, and soak five times in a row, mix the soaking liquid, and distill and recover the alcohol to obtain ethanol Concentrate 1311ml, mix the obtained ethanol concentrate with distilled water and then extract with analytical pure petroleum ether. The above-mentioned extraction was performed several times until the color of the petroleum ether layer was basically colorless. The extracts were mixed, and the solvent was recovered by distillation to obtain 9.60 g of the petroleum ether part and the residual concentrated solution. Ester extraction, each extraction volume ratio is 1:3 between the concentrated solution and petroleum ether, after mixing, let stand to separate layers, separate the petroleum ether layer,...

Embodiment 2

[0076] The preparation of the red live hemp extract emulsion of the present invention

[0077] Prescription: Ethyl acetate part extract, glycerin stearate, stearic acid, white petrolatum, liquid paraffin, glycerin, sodium lauryl sulfate, light phenylethyl ester, distilled water, etc.

[0078] Preparation method: take glyceryl stearate, stearic acid, white vaseline and liquid paraffin and heat and melt to form an oil phase. In addition, glycerin and distilled water were heated to 90°C, and sodium lauryl sulfate and phenethyl acetate were added to dissolve into the water phase. Then slowly pour the water phase into the oil phase, and stir until it condenses to obtain an emulsion matrix. Add the prepared ethyl acetate part extract into the above matrix, and stir evenly.

Embodiment 3

[0080] Preparation of red live hemp extract capsules of the present invention

[0081] Prescription: Paste powder of ethyl acetate part of red live hemp, starch, microcrystalline cellulose, talcum powder, sodium starch methylate, 75% ethanol.

[0082] Preparation method: Mix the raw and auxiliary materials according to a certain ratio and pass through a 100-mesh sieve, add wetting agent 75% ethanol, stir and granulate with a glass rod, dry, and fill capsules.

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Abstract

The invention provides a Honghuoma extract, which is an ointment obtained by immersing the Honghuoma with 95% medical alcohol, distilling and recycling alcohol, and extracting the residual concentrated solution obtained after extracting the obtained ethanol concentrated solution with petroleum ether with ethyl acetate. It is proved that the Honghuoma extract has the functions of analgesia, anti-inflammatory and immunosuppression.

Description

technical field [0001] The invention relates to traditional Chinese medicines, in particular to Chinese medicinal material extracts, especially Chinese medicinal material extracts with analgesic, anti-inflammatory and immunosuppressive effects. Background technique [0002] Red live hemp is distributed in Enshi Autonomous Prefecture, Hubei Province, Yichang, Shennongjia, Xiangfan and other places, mainly derived from the dry root of Laportea bulbifera (Sieb.et Zucc.) Wedd., the dry stem bark and leaves, Buds are also used medicinally. Hong Huo Ma is pungent, bitter and warm in nature and taste, and has the effects of expelling wind and removing dampness, promoting diuresis to reduce swelling, promoting blood circulation and relieving pain. It is picked locally and boiled in water to be used as medicine to treat rheumatoid joint pain, bruises, and dystrophic edema. The effect is remarkable. Due to the limitation of the distribution of medicinal material resources, there is ...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P29/00A61P37/06A61K125/00
Inventor 向明苏志强
Owner HUAZHONG UNIV OF SCI & TECH
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