Application of montmorillonite in preparing medicament

A technology for preparing medicine and montmorillonite, which is applied in the field of montmorillonite, and can solve problems such as diseases that have not yet existed

Inactive Publication Date: 2010-04-07
JINAN KANGZHONG PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The new use of montmorillonite disclosed in the Chinese patent approved in 2007 is to treat chronic renal failure diseases, which is also treated through digestive tract administration. So far, there has been no report on the treatment of diseases through other administration methods

Method used

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  • Application of montmorillonite in preparing medicament
  • Application of montmorillonite in preparing medicament
  • Application of montmorillonite in preparing medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0097] Embodiment 1 prepares montmorillonite nasal drops

[0098] Weigh 50 grams of montmorillonite and 5 grams of agar, add deionized water to 1000 ml, stir evenly, and then process the uniformly stirred mixed solution with a colloid mill to form a uniform liquid with a fineness of montmorillonite particles less than 20 μm. 60 Irradiate and sterilize, and pack to obtain montmorillonite nasal drops containing 5 grams of montmorillonite per 100 milliliters.

Embodiment 2

[0099] Embodiment 2 prepares montmorillonite nasal drops

[0100] Weigh 100 grams of montmorillonite, 10 g of methyl cellulose, add physiological saline to 1000 ml, stir well, and then ultrasonically process the evenly stirred mixture into a uniform liquid with montmorillonite particle fineness less than 45 μm, boil for 15 After being sterilized within 10 minutes, sub-package can obtain the montmorillonite nasal drops containing 10 grams of montmorillonite per 100 milliliters.

Embodiment 3

[0101] Embodiment 3 prepares montmorillonite nasal drops

[0102] Weigh 200 grams of montmorillonite, add water to 1000 milliliters, stir evenly, boil for 20 minutes to sterilize, then subpackage to obtain montmorillonite nasal drops containing 20 grams of montmorillonite per 100 milliliters.

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Abstract

The invention discloses application of montmorillonite in preparing a medicament, in particular application of the montmorillonite in preparing a medicament for preventing and treating cold. The cold comprises common cold and influenza. A prepared pharmaceutical dosage form of the montmorillonite for preventing and treating the cold is a montmorillonite nose drop; a prepared pharmaceutical dosage form of the montmorillonite for preventing and treating the cold is a montmorillonite spray; and a prepared pharmaceutical dosage form of the montmorillonite for preventing and treating the cold is a montmorillonite aerosol. The invention has the advantages that the invention explores the novel use on pharmaceutical montmorillonite and develops a novel application field; the montmorillonite nose drop or the montmorillonite spray or the montmorillonite aerosol can prevent and treat the common cold and the influenza; the montmorillonite only acts on the upper respiratory tract, is not absorbed by an organism, and has no toxicity and side effect; viruses and bacteria do not produce the drug tolerance; and the advantages of easily-obtained raw materials, low cost and low treatment cost are obviously superior to medicaments which are commonly used for preventing and treating the influenza at present.

Description

technical field [0001] The invention relates to a new application of montmorillonite, in particular to the application of montmorillonite in the preparation of medicines for preventing and treating colds. Background technique [0002] At present, the application of montmorillonite in medicine is through the digestive tract, mainly for the treatment of gastrointestinal diseases. The new use of montmorillonite disclosed in the Chinese patent approved in 2007 is to treat chronic renal failure disease and also to treat it through gastrointestinal drug administration. So far, there is no report on the treatment of diseases through other drug delivery methods. [0003] Montmorillonite is a typical 2:1 layered silicate mineral containing crystal water, which has many excellent properties such as high dispersion, suspension, swelling, cohesiveness, adsorption, and cation exchange. Montmorillonite has a long history of medicinal use. After oral administration, the drug can evenly co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K9/00A61K9/12A61P11/00A61P31/14A61P31/16
Inventor 张为胜李诗标许翠萍张梅雪张晶徐东峰
Owner JINAN KANGZHONG PHARMA TECH DEV
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