High-effective mosquito repelling liquid medicine

A technology of mosquito repellent water and extract, which is used in cosmetics, preparations for skin care, cosmetic preparations, etc.

Inactive Publication Date: 2010-05-05
TIANJIN HEERBO BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many types of mosquito repellent aquatic products on the market, but there are very few mo

Method used

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  • High-effective mosquito repelling liquid medicine
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  • High-effective mosquito repelling liquid medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Formula 1: Contains 7% DEET, 1% licorice extract, 1% Sophora flavescens extract, 0.5% menthol, 0.05% rose essential oil, 30% alcohol, and the balance is deionized water.

[0015] Formula 2: Contains DEET 2%, licorice extract 2%, Sophora flavescens extract 2%, menthol 0.5%, rosemary essential oil 0.05%, lavender essential oil 0.1%; alcohol 70%, the balance is deionized water .

[0016] Formula 3: Contains 5% DEET, 0.5% licorice extract, 0.5% Sophora flavescens extract, 0.5% menthol, 0.05% rose essential oil, 50% alcohol, and the balance is deionized water.

[0017] Formula 4: Contains 3% DEET, 1% glycyrrhizic acid, 1% matrine, 0.5% menthol, 0.05% tea tree essential oil, 40% alcohol, and the balance is deionized water.

[0018] Formula 5: Contains 4% DEET, 2% glycyrrhetinic acid, 1.5% oxymatrine, 1% menthol, 0.2% lemon essential oil, 60% alcohol, and the balance is deionized water.

[0019] Formula 6: Contains 6% DEET, 0.5% glycyrrhetinic acid, 1% matrine, 2% borneol, 0...

Embodiment 2

[0020] Embodiment two: pharmacological experiment result

[0021] 1. Anti-inflammatory activity

[0022] Test method: 50 mice were randomly divided into 5 groups, 10 in each group, respectively negative control group (preparation made of alcohol-water), strong mosquito repellent water low concentration group, strong mosquito repellent water concentration group, high-concentration group of strong mosquito repellent water, positive drug control group (compound piyanping ointment). The medication group used 0.5 grams of low, medium and high-concentration strong mosquito repellent water, 0.5 grams of external matrix in the model group, and 0.5 grams of Compound Piyanping ointment in the positive drug control group. After 1 hour, 0.03ml of xylene was dropped on the two sides of the right ear shell of the mouse to cause inflammation. After 2 hours, the mouse was killed by dislocation, and the round ears were removed from the symmetrical parts of the left and right ears with a 6mm d...

Embodiment 3

[0032] Embodiment 3 Mosquito repellent water efficacy test:

[0033] Test insects: female adults of Aedes albopictus (Aedes albopictus) who have not sucked blood 4-5 days after eclosion.

[0034] Testing basis "Pesticide Registration Hygienic Insecticide Indoor

[0035] Drug efficacy evaluation" (GB / T 17322.10-1998)

[0036] Testing conditions: ambient temperature 26±1°C, relative humidity 65±5%.

[0037] Experimental results:

[0038] Average frequency of bites at different times (times / 2 minutes)

[0039]

[0040] Experimental results:

[0041]The efficacy of the powerful mosquito repellent water against Aedes albopictus was evaluated in the laboratory according to GB / T17322.10-1998 in "Indoor efficacy evaluation of insecticides for pesticide registration and sanitation". The formulas 1#, 3#, 5# and The repellent effect of 6# meets the A-level standard, and the repellent effect of formula 2# and 4# can be maintained for 4-5 hours.

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Abstract

The invention relates to high-effective mosquito repelling liquid medicine which is characterized by comprising the following components by weight percent: 2%-7% of N, N-Diethyl-m-toluamide, 0.2%-2% of glycyrrhiza extract (0.1%-90% of glycyrrhizinic acid or glycyrrhetinic acid or physiologically acceptable salt thereof), 0.2%-2% of flavescens extract (0%-90% of matrine or oxymatrine or physiologically acceptable salt thereof), 0%-50% of menthol or borneol and 0.01%-2% of plant essential oil. The high-effective mosquito repelling liquid medicine is the hormone-free preparation made of pure Chinese herbal medicine for external application and is prepared by uniquely combining the high-effective repellent with the components having the anti-inflammatory, the antibacterial and the antipruritic effect, thereby being innovative. The high-effective mosquito repelling liquid medicine of the invention has the function of repelling the mosquito, relieving the itching, refreshing the consciousness and protecting the skin from the insect bite and can repel the mosquito for 5-7 hours. The high-effective mosquito repelling liquid medicine of the invention is non-toxic to the skin and mucous membrane, can not cause the allergic reaction and has higher stability.

Description

technical field [0001] The invention relates to the field of daily chemical industry, in particular to a powerful mosquito repellent water with repellent and antipruritic effects, which contains a repellent and is matched with a herbal drug composition. Background technique [0002] Insects have caused many problems to humans. In addition to causing direct harassment and harm to humans, they will also bring other troubles to varying degrees. Such as affecting sleep, spreading diseases, and those who are severely bitten by insects will directly pose a threat to human health and life. Therefore, human beings have been constantly looking for various effective ways to resist the annoyance of insects. [0003] The main method of combating insects is the use of insecticides. However, insecticides are toxic, and insecticide is an extreme method, which is not suitable for general use in human daily life. At present, insect repellents are often used to prevent insects from staying...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q17/02A61K8/42A61K8/34
Inventor 刘岱琳陈虹谢文利高颖张静泽曹波白淑芳
Owner TIANJIN HEERBO BIOLOGICAL TECH CO LTD
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