Elk horn active site and preparation method and application thereof

Abstract

The invention discloses an elk horn active site and a preparation method and application thereof. The elk horn active site uses an elk horn of 3 to 5 years as a raw material and is prepared by the following steps of: adding ethanol in an amount which is 6 to 10 times that of the elk horn into the elk horn to perform reflux and extraction, combining the extract, concentrating the extract to obtain extractum, adding water into the extractum to suspend the extractum, adding petroleum ether into the solution and extracting the solution for 1 to 3 times, reclaiming the petroleum ether solution to obtain a petroleum ether extracting site, then adding ethyl acetate into the solution and extracting the solution for 1 to 3 times, adding n-butanol into the solution and extracting the solution for 1to 3 times, reclaiming the n-butanol to obtain an n-butanol extracting site, and combining the petroleum ether extracting site and the n-butanol extracting site to obtain the elk horn active site. Pharmacological experiments show that the elk horn active site provided by the invention can obviously enhance the function of a yin deficiency model mouse on stress injury resistance, has obvious promotion effect on the immune system of the mouse, and is expected to be developed to form a new medicament for treating yin deficiency diseases or low immunity diseases.

Description

technical field [0001] The invention relates to a traditional Chinese medicine elk horn, in particular to an active part of elk horn, a preparation method thereof and an application thereof. Background technique: [0002] Elk antlers are the ossified and exfoliated old horns of the deer family elk (Elaphurus davidianus Milne-Edwards). Elk horn is a traditional tonic Chinese medicinal material. It has been used as medicine for more than a thousand years until the extinction of elk in China at the end of the Qing Dynasty. Traditional Chinese medicine believes that elk antler is warm and salty in nature, enters the liver and nourishes the kidneys, can nourish the depleted yin and fluid, so it can calm the mind and treat symptoms such as dysphoria, heat, and irritability. Due to the extinction of elk in China in modern times, the modern medicinal records of elk horns and related research are very rare. In modern times, Zhang Dechang and others compared the composition content ...

AI Technical Summary

Problems solved by technology

However, there are no research reports on the active parts, active substance basis and mechanism of action of elk horns. Therefore, it is necessary to further study the active parts and active substances of elk horns on the existing basis to provide a scientific basis for restoring the medicinal use of elk antlers. and its clinical efficacy

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