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Cough-relieving Chinese medicinal composition and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of cough-relieving traditional Chinese medicine composition and its preparation, can solve the problems of single dosage form, inability to be used by patients, and limited promotion, and achieve the effects of good quality, good drug effect, and improved production efficiency

Active Publication Date: 2010-10-20
TEYI PHARMACEUTICAL GROUP CO LTD
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  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

[0004] Zhikebao Tablets is an exclusive variety in the country and is a national essential medicine, but the dosage form is single, and some patients cannot use it, which limits the promotion of this medicine in cough treatment

Method used

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  • Cough-relieving Chinese medicinal composition and preparation method thereof

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preparation example Construction

[0016] The present invention is a kind of preparation method of antitussive traditional Chinese medicine composition, comprises the following steps:

[0017] (1) Prepare the following medicinal materials: poppy husk, aster, licorice, tangerine, hundred leaves, schisandra, bellflower, aurantium, tangerine peel, nepeta, peucedanum, dried ginger, ammonium chloride, mint oil.

[0018] (2) Put the pure medicinal material of poppy shell in a multi-functional extraction tank, add 60% ethanol, 1:8~1:10 solid-liquid ratio, heat reflux extraction twice, each time for 3.5-4.5 hours, filter the alcohol extract, Merge and discard the dregs.

[0019] (3) Pump the ethanol extract of poppy shell into the alcohol recovery tower to recover ethanol until the ethanol temperature reaches 85-90°C, transfer it to the double-effect evaporator, control the steam pressure ≤ 0.2MPa, vacuum degree: first effect -0.04~ -0.08MPa, second effect -0.06~-0.08MPa, concentrate to a relative density of 1.05~1.10...

Embodiment 1

[0030] Example 1 of the present invention, the antitussive traditional Chinese medicine honey refining paste of poppy shell extract, aster, licorice, tangerine, hundred leaves, schisandra, bellflower, aurantium, tangerine peel, nepeta, peucedanum, dried ginger, ammonium chloride, mint oil preparation

[0031] a) Preparation of No. 1 clear ointment powder: put the pure medicinal material of poppy shell into a multifunctional extraction tank, add 60% ethanol, 1:8~1:10 solid-liquid ratio, heat reflux extraction twice, each time for 4 hours, alcohol extraction The solution was filtered through 120 mesh, the filtrates were combined, and the dregs were discarded. Pump the alcohol extract into the alcohol recovery tower to recover ethanol until the temperature of ethanol reaches 85-90°C, transfer it to the double-effect evaporator, control the steam pressure ≤ 0.2MPa, vacuum degree: -0.04-0.08MPa for the first effect, -0.04-0.08MPa for the second effect Effectiveness -0.06~-0.08MPa,...

Embodiment 2

[0037] Example 2 Preparation of cough-relieving traditional Chinese medicine capsules of poppy shell extract, aster, licorice, tangerine, hundred-head, schisandra, bellflower, aurantium, tangerine peel, nepeta, peucedanum, dried ginger, ammonium chloride, and peppermint oil of the present invention

[0038] a) Preparation of No. 1 clear ointment powder: put the pure medicinal material of poppy shell into a multifunctional extraction tank, add 60% ethanol, 1:8~1:10 solid-liquid ratio, heat reflux extraction twice, each time for 4 hours, alcohol extraction The liquid was filtered through 120 mesh, the filtrates were combined, and the dregs were discarded. Pump the ethanol extract of poppy shell into the alcohol recovery tower to recover ethanol until the temperature of ethanol reaches 85-90°C, transfer it to the double-effect evaporator, control the steam pressure ≤ 0.2MPa, vacuum degree: first effect -0.04-0.08MPa , Second effect -0.06~-0.08MPa, concentrated to a relative densi...

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Abstract

The invention discloses a cough-relieving Chinese medicinal composition and a preparation method thereof. A conventional prescription, namely, a cough-relieving medicament is subjected to modern extraction and preparation processes, such as hot reflux, double effect evaporation, spray drying and the like to prepare extract and the extract is prepared into a corresponding formulation. The preparation method has the advantages of extracting medicinal materials by a more reasonable process, greatly improving production efficiency, completely extracting active ingredients compared with the conventional process of cough-relieving tablets and enhancing the quality of the medicament, so that the method can bring medicament effect into full play and be widely applied to clinical work in a better way.

Description

technical field [0001] The invention relates to a Chinese medicine composition, especially a cough-relieving Chinese medicine composition and a preparation method thereof, as well as a new derived dosage form and a new administration mode of the Chinese medicine composition. Background technique [0002] In recent years, due to the increasingly serious air pollution of the earth, the continuous increase of industrial and civil pollution sources, coupled with poor environmental governance and other factors, the living environment of human beings has deteriorated, the immune function of the human body has been destroyed, and the incidence of respiratory diseases has shown an obvious upward trend. The mortality rate of the disease is also increasing year by year. At present, respiratory diseases have become one of the major "killers" of human beings. According to the statistics of the national health department, nearly 300 million people in my country are infected with respirat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P11/14A61K33/02
Inventor 许丹青
Owner TEYI PHARMACEUTICAL GROUP CO LTD
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