Supermolecular gel used for protecting photostability of vitamin A derivatives and its preparation method

Abstract

The invention provides a supermolecular gel used for protecting the photostability of vitamin A derivatives. The supermolecular gel is a non-flowing quasi solid gel formed by molecular assembly of gel factors in a mixed solvent of organic solvent and absolute ethyl alcohol. The supermolecular gel used for protecting the photostability of the vitamin A derivatives has the characteristics of good biocompatibility, simple manufacture, easy operation, less introduced chemical substances, no toxin or harm, good protection effect, thermal reversibility and the like; when the phase inversion temperature of the supermolecular gel approaches body temperature, the gel is converted into solution, and the vitamin A derivatives are easy to release onto skin surface; the encapsulation quantity of the vitamin A derivatives can reach 100 percent, and the release quantity can also be regulated according to the concentration of the encapsulated vitamin A derivatives and the concentration of the gel factors; and the supermolecular gel can be widely applied to the fields of biomedical materials, cosmetics and the like.

Description

technical field [0001] The invention relates to a supramolecular gel for protecting the photostability of vitamin A derivatives and a preparation method thereof. Background technique [0002] Vitamin A derivatives (Vitamin A, Retinol) such as vitamin A acid, vitamin acetate, vitamin A palmitate, etc., are a fat-soluble vitamin necessary for the human body, and all contain conjugated unsaturated double bonds. These compounds affect almost all tissue cells of the body in different ways. The most important physiological functions include: maintaining vision, promoting growth and development, maintaining the integrity and soundness of epithelial structure, strengthening immunity and scavenging free radicals. Vitamin A in the narrow sense refers specifically to retinol, while vitamin A in the broad sense includes a series of derivatives of retinol, including β-carotene, some provitamins such as carotenoids, retinal, and some of retinol Esters such as vitamin A derivative palmit...

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a supramolecular gel for protecting the photostability of vitamin A derivatives, and at the same time provide a preparation method for this supramolecular gel. The present invention also provides a supramolecular gel of photostable vitamin A derivatives Gel, to overcome the shortcomings of the existing methods for protecting the photostability of vitamin A derivatives, such as complicated process, introduction of a large number of other chemical components, poor compatibility, and difficult diffusion of vitamin A from the protective matrix to the skin surface

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