Pediatric compound chicken's gizzard-membrane chewable tablets and preparation method thereof

A technology of chewable tablets and compound chicken, which is applied in the direction of medical formula, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., which can solve the problem of poor taste of powders and tablets, inconvenience of powder dosage, and lack of efficacy Treatment effects and other issues to achieve the effect of ensuring curative effect, controllable product quality, and clinical drug safety

Active Publication Date: 2011-01-12
HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is inconvenient to divide the doses of powders, and it is difficult to accept tablets for children, and the taste of powders and tablets is very bad, and patients, especially children, have poor compliance and often refuse to take them, which will not achieve the original therapeutic effect

Method used

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  • Pediatric compound chicken's gizzard-membrane chewable tablets and preparation method thereof
  • Pediatric compound chicken's gizzard-membrane chewable tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] In this example, children's compound Ji Nei Jin chewable tablets were prepared, and the following components were used:

[0044] Chicken gold 85g

[0045] Six Divine Comedies 165g

[0046] Sucrose 280g

[0047] Mannitol 640g

[0048] Citric acid 12g

[0049] Essence (strawberry flavor) 4g

[0050] Pigment (milk chocolate brown) 6.25g

[0051] 2% sodium carboxymethylcellulose 125ml

[0052]Magnesium Stearate 12g

[0053]

[0054] A total of 1000 pieces were made

[0055] The preparation process of this embodiment:

[0056] The above-mentioned gallinaceous gold, Liushenqu, and sucrose are pulverized respectively, and after passing through a No. 5 sieve, mix well; About 125ml of 2% sodium carboxymethylcellulose solution of chocolate brown) is used as a soft material for binder system, granulated with 18 mesh sieve, air-dried at 60°C, granulated with 16 mesh sieve, added magnesium stearate and mixed evenly, pressed Slice, inspec...

Embodiment 2

[0058] In this example, children's compound Ji Nei Jin chewable tablets were prepared, and the following components were used:

[0059] Chicken gold 80g

[0060] Six Divine Comedies 160g

[0061] Sucrose 240g

[0062] Mannitol 600g

[0063] Citric acid 10g

[0064] Essence (strawberry flavor) 3g

[0065] Pigment (milk chocolate brown) 6g

[0066] 2% sodium carboxymethylcellulose 100ml

[0067] Magnesium Stearate 10g

[0068]

[0069] A total of 1000 pieces were made

[0070] The preparation process of this embodiment:

[0071] The above-mentioned gallinaceous gold, Liushenqu, and sucrose are pulverized respectively, and after passing through a No. 5 sieve, mix well; Brown) about 100ml of 2% sodium carboxymethylcellulose solution is used as a binder to make a soft material, granulated with a 18-mesh sieve, air-dried at 60°C, granulated with a 16-mesh sieve, added magnesium stearate, mixed evenly, and pressed into tablets , che...

Embodiment 3

[0073] In this example, children's compound Ji Nei Jin chewable tablets were prepared, and the following components were used:

[0074] Chicken Gold 90g

[0075] Six Divine Comedies 170g

[0076] Sucrose 320g

[0077] Mannitol 680g

[0078] Citric acid 14g

[0079] Essence (strawberry flavor) 5g

[0080] Pigment (milk chocolate brown) 6.50g

[0081] 2% sodium carboxymethylcellulose 150ml

[0082] Magnesium Stearate 14g

[0083]

[0084] A total of 1000 pieces were made

[0085] The preparation process of this embodiment:

[0086] The above-mentioned gallinaceous gold, Liushenqu, and sucrose are pulverized respectively, and after passing through a No. 5 sieve, mix well; Chocolate brown) about 150ml of 2% sodium carboxymethyl cellulose solution is used as a soft material for binder system, granulated with 18 mesh sieve, air-dried at 60°C, granulated with 16 mesh sieve, added magnesium stearate and mixed evenly, pressed Slice,...

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PUM

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Abstract

The invention belongs to the field of Chinese patent medicine preparations and relates to pediatric compound chicken's gizzard-membrane chewable tablets and a preparation method thereof. The pediatric compound chicken's gizzard-membrane chewable tablets comprise the following components in parts by weight: 80-90 parts of chicken's gizzard-membrane, 160-170 parts of medicated leaven, 240-320 parts of first filler, 600-680 parts of second filler, 10-14 parts of flavoring agent, 3-5 parts of fragrance, 6-6.5 parts of pigments, 10-14 parts of lubricant and an appropriate amount of binding agent. The pediatric compound chicken's gizzard-membrane chewable tablets have the advantages of significantly improving the bioavailability and the efficacy, being easily absorbed, having rapid onset of action and being easy to be accepted by children.

Description

technical field [0001] The invention belongs to the field of Chinese patent medicine preparations, and relates to a Chinese patent medicine chewable tablet and a preparation process thereof, in particular to a children's compound Ji Nei Jin chewable tablet and a preparation process thereof. Background technique [0002] Anorexia in children is a common disease in pediatrics. Its incidence rate is relatively high, which affects the normal development and healthy growth of children. It has been widely concerned by the society and the medical field, and the demand for its therapeutic drugs is also increasing. In recent years, there have been many domestic researches on the treatment of anorexia in children, but there is currently a lack of effective western medicines in clinical practice, and there is also a lack of Chinese patent medicines for children with spleen-stomach disharmony and spleen dysfunction syndrome, which account for the majority of children with anorexia. effe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61K9/20A61K47/38A61P1/14A61K35/37A61K35/57
Inventor 江鸿
Owner HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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