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Coptis alkaloid and ferulic acid compound with glucose-lowering effect

A technology of Coptis alkaloids and ferulic acid, applied in the field of complexes, can solve the problems such as the compounding of ferulic acid and Coptis alkaloids, and the hypoglycemic activity of the complex has not been seen, and achieve low cost and good hypoglycemic activity. Effect

Inactive Publication Date: 2012-06-06
SOUTHWEST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, so far, there has been no report on the compounding of ferulic acid and coptis alkaloids, nor has there been any literature report on the research on the hypoglycemic activity of the compound

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Berberine 90g, ferulic acid 10g, after mixing evenly, pulverize to 80 mesh, put into No. 0 capsule, 0.5g per capsule. Taking 0.5 grams per person per day can effectively lower blood sugar.

Embodiment 2

[0024] Palmatine 50g, ferulic acid 50g, after mixing evenly, pulverize to 80 mesh, put into No. 0 capsule, 0.5g per capsule. Taking 1 gram per person per day can effectively lower blood sugar.

Embodiment 3

[0026] Coptisine 10g, ferulic acid 90g, mixed evenly, crushed to 80 mesh, filled with 0 capsules, 0.5g per capsule. Taking 5 grams per person per day can effectively lower blood sugar. .

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PUM

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Abstract

The invention discloses a coptis alkaloid and ferulic acid compound with glucose-lowering activity, which comprises the following components in percentage by weight: 0.1 to 99.9 percent of coptis alkaloid and 0.1 to 99.9 percent of ferulic acid, wherein the coptis alkaloid contains berberine or coptisine or palmatine or jatrorrhizine or the sum of four coptis alkaloids, or is total coptis alkaloids extracted from coptis. The compound has the advantages of better glucose-lowering effect compared with that of the coptis alkaloid or ferulic acid, and obvious glucose-lowering effect according to administration in a dosage of 0.5 to 5 grams every person per day.

Description

technical field [0001] The invention relates to a compound with hypoglycemic effect, in particular to a compound of coptis alkaloids and ferulic acid. Background technique [0002] Diabetes has become a major problem threatening human health. The number of diabetic patients in my country ranks second in the world, and the increase rate is astonishing: according to preliminary statistics, the total number of diabetic patients in my country is about 80 million, mainly type 2 diabetes; in 1979, the incidence of type 2 diabetes in my country was only 1.00%. The prevalence has risen to 2.5%, and has grown to more than 5% so far. It is a great contribution to mankind to develop natural drug compound preparations with better hypoglycemic effects and make efforts for the prevention and treatment of diabetes. [0003] Coptis chinensis is bitter in taste and cold in nature, enters the heart, liver, stomach, and large intestine meridian, can clear away heat and dampness, relieve fire ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/4375A61K36/718A61P3/10
Inventor 李学刚叶小利
Owner SOUTHWEST UNIV
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