Preparation method of medicine for preventing and controlling liver and gall syndromes of aquatic animals

Abstract

The invention relates to a preparation method of a medicine for preventing and controlling liver and gall syndromes of aquatic animals. The preparation method comprises the following steps of: 1. weighing the following raw material medicines in parts by weight: 200-400 parts of astragalus, 300-400 parts of liquorice and 100-200 parts of silybum marianum; 2. placing all the raw material medicines weighed in the step 1 in a fully-closed powder device, and mechanically extruding and knocking to crush all the weighed raw material medicines into micropowder at 50 DEG C below zero to 30 DEG C by adopting a cell wall breaking micropowder production process; and 3. weighing 10-30 parts of glucurolactone and 100-200 parts of starch in parts by weight; and mixing the weighed glucurolactone and starch with the astragalus, liquorice and silybum marianum micropowder crushed in the step 2, and finally stirring evenly to obtain the finished product. The invention has the advantages of reasonable formula, simple preparation and remarkable effect; by adopting the cell wall breaking micropowder production process, the dissolution rate of the raw material medicines is increased, and the biological availability of effective components is improved; moreover, traditional Chinese medicines and western medicines work together to achieve good prevention and control effects on liver and gall syndromes of aquatic animals without medicine residue.

Description

technical field [0001] The invention relates to a preparation method of an aquatic animal medicine, in particular to a preparation method of a medicine for preventing and treating hepatobiliary syndrome of an aquatic animal. Background technique [0002] Hepatobiliary syndrome is a common disease in intensive fish farming. The main organs such as the liver and gallbladder of the diseased fish have serious lesions and damages, resulting in a decrease in fish feed intake, or even no food intake, and a decline in the body's disease resistance. Other pathogenic bacteria are more likely to infect the fish. Fish with hepatobiliary syndrome are often accompanied by symptoms such as bleeding, rotten gills, enteritis, and rotten tail. When drugs, germs (including parasites) and other adverse stimuli to the fish body will aggravate the hazards of hepatobiliary syndrome and cause fish death, it is especially serious under stress conditions such as pond division and fishing. [0003] ...

AI Technical Summary

Problems solved by technology

The current drugs for the prevention and treatment of this type of aquatic animal hepatobiliary syndrome are still unsatisfactory in terms of drug efficacy and drug residues.