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Efficient scurf removing and itch relieving composite as well as preparation method and application thereof in shampoos

An anti-dandruff, antipruritic, and shampoo technology, applied in the field of daily chemicals, can solve the problems of dry hair, covering shampoo pearls, lack of anti-dandruff effect, etc. The effect of the crumb effect

Active Publication Date: 2012-04-25
广州增城潮徽生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when zinc pyrithione (ZPT) is used in shampoo formulations, there are still some technical defects: (ZPT) will settle in the formulation; it is easy to change color when it encounters iron ions, and it will cause serious problems if it is not handled carefully or the equipment requirements are not high. Discoloration occurs; it is unstable to light and will cover the pearly luster of the shampoo. In addition, its degreasing ability is strong, and long-term use will cause dry hair and other problems
However, water-soluble chitosan derivatives are generally not used alone, mainly because the anti-dandruff effect is lacking, and the effect of zinc pyrithione (ZPT) or bispyridinethione (SPT) cannot be achieved yet.

Method used

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  • Efficient scurf removing and itch relieving composite as well as preparation method and application thereof in shampoos
  • Efficient scurf removing and itch relieving composite as well as preparation method and application thereof in shampoos
  • Efficient scurf removing and itch relieving composite as well as preparation method and application thereof in shampoos

Examples

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Effect test

example 1

[0044] (1) Preparation of water-soluble chitosan derivatives: 3g chitosan was added in a 500ml there-necked flask, 300g distilled water was added, stirred; 1.5g glacial acetic acid was slowly added dropwise to dissolve the chitosan; then 10g acrylic acid and 5g propylene were added Amide, add 0.03g ammonium persulfate initiator, nitrogen protection, heat up to 55°C; stir and react at constant temperature for 5.0h, cool down to obtain chitosan / acrylic acid / acrylamide polymer aqueous solution. Add 100ml of absolute ethanol to the obtained polymer aqueous solution, let it stand for 3 hours to precipitate the polymer, filter it with suction, wash the obtained solid three times with absolute ethanol, and freeze-dry to obtain chitosan / acrylic acid / acrylamide polymer .

[0045] (2) Preparation of high-efficiency anti-dandruff and antipruritic composition: 50 g of bispyridinethione (commercially available, cosmetic grade, the same below) with a mass percentage of 99.9% and a particle ...

Embodiment 2

[0047](1) Preparation of water-soluble chitosan derivatives: 10g chitosan is added in a 500ml there-necked flask, 300g distilled water is added, stirred; 5.0g glacial acetic acid is slowly added dropwise to dissolve the chitosan; 10g acrylic acid and 12g 2- Acrylamido-2-methylpropanesulfonic acid, nitrogen protection, heating up to 85°C, adding 0.25g of initiator azobisisobutyronitrile, stirring at constant temperature for 10h, cooling down to obtain chitosan / acrylic acid / 2-propylene Amino-2-methylpropanesulfonic acid polymer aqueous solution; the obtained polymer aqueous solution was added to 100ml of absolute ethanol, and stood for 8h to precipitate the polymer, suction filtered, and the obtained solid was repeatedly washed three times with absolute ethanol, Freeze drying to obtain chitosan / acrylic acid / 2-acrylamide-2-methylpropanesulfonic acid polymer;

[0048] (2) Preparation of high-efficiency anti-dandruff antipruritic composition: 40 g of bispyridinethione with a partic...

Embodiment 3

[0050] (1) Preparation of water-soluble chitosan derivatives: 5g chitosan was added in a 500ml there-necked flask, 300g distilled water was added, stirred; 3.0g glacial acetic acid was slowly added dropwise to dissolve the chitosan; 10g acrylic acid and 15g dimethylformamide were added Diallyl ammonium chloride, under nitrogen protection, heated up to 75°C, added 0.1g of initiator potassium persulfate, stirred at constant temperature for 7 hours, cooled to obtain chitosan / acrylic acid / dimethyldiallyl chloride Ammonium polymer aqueous solution; add 100ml of absolute ethanol to the obtained polymer aqueous solution, let it stand for 5 hours to precipitate the polymer, filter it with suction, wash the obtained solid three times with absolute ethanol, and freeze-dry to obtain chitosan / acrylic acid / Dimethyldiallylammonium Chloride Polymer.

[0051] (2) Preparation of high-efficiency anti-dandruff antipruritic composition: 50 g of bispyridinethione with a mass percentage of 90.0% ...

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Abstract

The invention discloses an efficient scurf removing and itch relieving composite as well as a preparation method and an application thereof in shampoos. The efficient scurf removing and itch relieving composite comprises bispyrithione and a water-soluble chitosan derivative, and has the following advantages that (1) the composite is a solid powder, thus being convenient to use; (2) the composite can be evenly distributed in the shampoos, has enough contact surface with bacteria and fungi which cause the scurf during hair washing, thus being capable of giving a full play to the efficacy; (3) the efficacies of the antibiosis, the moisture preservation, and the chelation and the like of the water-soluble chitosan derivative are combined with the efficacies of the bispyrithione, thus improving the scurf removing effect of the bispyrithione, lowering the degrease capability of the bispyrithione, reducing the sensitive degree of the bispyrithione to the metal icons, and achieving the purpose of synergism; and (4) the composite is used to greatly improve the color stability in the shampoos, and has less acrimony to the skin. The shampoos prepared by the efficient scurf removing and itch relieving composite have preferable stability as well as scurf removing and itch relieving properties.

Description

technical field [0001] The invention relates to the technical field of daily chemicals, in particular to a high-efficiency anti-dandruff and anti-itch composition and its preparation and application in shampoo. Background technique [0002] The surface of the human scalp and the internal structure of the scalp form a complete ecosystem. There are secretions of sebaceous glands, dust, dirt, various bacteria and so on on the surface. The scalp is an active tissue that is constantly renewing and aging, and is easily affected by the outside world. Through normal metabolism, the excreted secretions accumulate on the surface of the scalp. Dander and scalp metabolites, the fungus in turn uses dust mites and human dander as the main source of nutrition, thus forming a miniature ecosystem on the human scalp. It is generally believed that symbiotic dermatophytes, such as dermatophyte ovale and other dermatophytes, if their growth is unbalanced, enter the hair follicles, and their ana...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/73A61K8/81A61K8/49A61K8/89A61Q5/02A61K8/42A61K8/46
Inventor 程建华曹文丹谢培镇张鹏
Owner 广州增城潮徽生物技术有限公司
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