Functional nutritional agent for regulating disharmony of intestinal florae and enhancing immunity and preparation method thereof

Abstract

The invention discloses a functional nutritional agent for regulating the disharmony of intestinal florae and enhancing immunity and a preparation method thereof. The functional nutritional agent is prepared from four traditional Chinese medicines of Szechwan tangshen root, largehead atractylodes rhizome, Indian buead and honey-fried licorice in a weight ratio of 2:2:2:1 and spirulina, wherein a weight ratio of the four traditional Chinese medicines to the spirulina is 1-6:1-6. The preparation method comprises the following steps of: concentrating decoction of the four traditional Chinese medicines, inoculating lactobacillus to the concentrated decoction, and fermenting to obtain fermentation liquor of four gentlemen decoction; performing ultramicro crushing on the spirulina, inoculating bifidobacterium and fermenting to prepare fermentation liquor of the spirulina; and mixing the fermentation liquor of the four gentlemen decoction and the fermentation liquor of the spirulina, centrifuging to remove thalli, inactivating enzyme and drying to obtain the functional nutritional agent. The functional nutritional agent can prevent and correct the disharmony of the intestinal florae and enhance immunologic function, and also can protect hematopoietic function and blood liquidity, balance the metabolism of trace elements and improve endocrine function, so the functional nutritional agent is suitable for crew who perform long-distance navigation on naval vessels or submarines.

Description

technical field [0001] The invention relates to a functional nutritional agent, in particular to a functional nutritional agent capable of regulating intestinal flora imbalance and enhancing immunity, and also relates to a preparation method of the functional nutritional agent. Background technique [0002] In the previous research work, the inventor took the ships or submarine crews of long-term voyage operations on the surface and underwater as objects, and systematically investigated and compared the effects of surface and long-term voyage conditions on the crew's cellular immunity, humoral immunity, whole blood cell components, blood Effects of rheology, peripheral blood thyroid axis, adrenal axis, gonadal axis hormone levels, normal intestinal flora and mental health status. The survey results show that most of the above-mentioned indicators have obvious abnormalities after the long-term voyage of the ship or submarine crew, among which the immune function and intestina...

AI Technical Summary

Problems solved by technology

At present, commercially available spirulina preparations are mainly spirulina powder or tablets or capsules made of spirulina powder according to conventional preparation methods. The preparation method has the following problems: ①The protein contained in spirulina mainly exists in the spirulina cells However, the cell wall of Spirulina is thicker, the inner wall contains peptidoglycan, and the outer wall contains lipoprotein, lipopolysaccharide and colloidal sheath. Simple crushing method can not destroy the cell wall of Spirulina, and it is difficult to release intracellular protein; ②The protein contained in Spirulina Most of them are high proteins with a molecular weight of more than 50,000, which can only be absorbed and utilized by the human body after being digested into oligopeptides with physiological functions, and the human body's own digestibility is very low; ③ some bioactive peptides are in an inactive state Exist in the polypeptide chain of protein, only when it is released through the action of protease, can it exert biological activity

[0005] So far, apart from the research results of the inventor's research group, there is no combination of Sijunzi decoction and spirulina to make a functional nutritional agent at home and abroad, and to use it for long-haul ships or submarine crews and other similar special operations and living environments Related research reports on regulating intestinal flora imbalance and enhancing immune function

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