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Application of camellia oleifera peel extract

The technology of extract and Camellia oleifera is applied in the field of use of the Camellia oleifera extract to prepare medicines, which can solve the problems of lack of biological activity and medicinal value, and achieve the effects of stable performance, reducing resource waste and protecting cardiovascular and cerebrovascular.

Active Publication Date: 2013-04-10
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

It has been reported that Camellia oleifera is used to produce chemical raw materials such as furfural, xylitol, activated carbon, potassium carbonate and potassium pyrophosphate and cultivate edible fungi, but the research on its biological activity and medicinal value is still very lacking

Method used

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  • Application of camellia oleifera peel extract
  • Application of camellia oleifera peel extract
  • Application of camellia oleifera peel extract

Examples

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Embodiment Construction

[0029] The present invention will be further elaborated below by example. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. Unless otherwise defined, all professional and scientific terms used herein have the same meanings as commonly understood by those skilled in the art. In addition, any methods and materials similar or equivalent to those described can be applied to the method of the present invention. The preferred implementation methods and materials described herein are for demonstration purposes only.

[0030] 1. Inhibitory effect of Camellia oleifera extract on 5α-reductase

[0031] 1.15 Preparation of α-reductase

[0032] Three clean-grade female SD rats were taken, fasted without food and water overnight, and then killed by dislocation of the cervical vertebrae. The liver was taken out and cut into pieces on ice. Homogenize with pre-cooled buffer solutio...

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Abstract

The invention discloses application of a camellia oleifera peel extract. The camellia oleifera peel extract serving as a 5-alpha-reductase inhibitor can be used for preparing medicaments for treating prostatitis, benign prostatic hyperplasia and prostate cancers medicaments or daily health products for treating acnes or medicaments or daily health products for treating androgenetic alopecia.

Description

technical field [0001] The invention relates to a new application of the extract of Camellia oleifera, in particular to the application of the extract of Camellia oleifera in the preparation of medicines, health care products and daily chemical products, and in the treatment of diseases related to 5α-reductase. Background technique [0002] 5α-reductase (5α-reductase, 5AR) is an NADPH-dependent enzyme that can catalyze testosterone (T) in vivo to generate more active dihydrotestosterone (DHT). Inhibiting the activity of this enzyme can reduce the generation of DHT, and then affect the diseases related to DHT, such as benign prostatic hyperplasia, prostate cancer, acne, male hair loss and so on. There are three isozymes of 5α-reductase, 5α-reductase I and 5α-reductase II and 5α-reductase III. Among them, type I enzymes are mainly expressed in non-reproductive tissues, such as liver and non-genital skin; type II enzymes are mainly expressed in reproductive tissues, such as pr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/82A61K8/97A61P13/08A61P17/10A61P17/14A61P35/00A61Q7/00A61Q19/00
Inventor 沈建福罗晓伟吴晓琴陈秋平陈忠海肖仁显车璐李利勉
Owner ZHEJIANG UNIV
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