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Silkworm cocoon health-care preparation and production method thereof

A silkworm cocoon and preparation technology, applied in the field of health care preparations, can solve the problems of large adverse reactions of immediate release preparations

Active Publication Date: 2013-04-10
曾光强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3. Niacin is the earliest blood-lowering drug used. It can reduce triglyceride and cholesterol levels. However, the immediate-release preparations of the drug have serious adverse reactions and are basically not used alone. Taking it with food can reduce its gastrointestinal adverse effects reaction
[0004] It can be seen from the above that although Western medicine has a quick effect on the treatment of hyperlipidemia and cholesterol, there are many side effects, especially statins, some of which have become the most worrying and concerned safety issues

Method used

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  • Silkworm cocoon health-care preparation and production method thereof

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Experimental program
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Effect test

preparation Embodiment 1

[0064] Preparation of enzymatically hydrolyzed cocoon fibroin 1

[0065] The solid cocoon silk fibroin taken from the silk reeling factory, the solid silk fibroin is treated with 0.5% Na at 90-100°C before use3 CO 3 The solution is degummed to cocoon silk fibroin for 20-30 minutes at a solid-to-liquid weight ratio of 1:10, and filtered to obtain silk fibroin solids, which are dissolved in CaCl with a weight content of 20-40% at 40-70°C 2 In aqueous solution (according to 1 weight of silk fibroin: 10 weights of CaCl2 aqueous solution), the time is 1 hour, and then every kilogram of CaCl 2 Add 0.5 g of papain to the aqueous solution for enzymatic hydrolysis at room temperature for 2 hours, and use a MWCO 500 ultrafiltration membrane to filter out small molecular substances such as pigments and peculiar smells. The enzymatic silk fibroin obtained by drying is preserved for future use.

preparation Embodiment 2

[0067] The solid cocoon silk fibroin taken from the silk reeling factory is treated with 1% Na at 70-85°C before use. 3 CO 3 The solution is degummed to cocoon silk fibroin for 20-30 minutes at a solid-to-liquid weight ratio of 1:15, and filtered to obtain silk fibroin solids, which are dissolved in CaCl with a weight content of 20-40% at 40-70°C 2 In aqueous solution (according to 1 part by weight of silk fibroin: 10 parts by weight of CaCl2 aqueous solution), the time is 1.5 hours, and then every kilogram of CaCl 2 Add 1 gram of papain to the aqueous solution for enzymatic hydrolysis at room temperature for 1 hour, use MWCO 500 ultrafiltration membrane to filter out small molecular substances such as pigment and peculiar smell, and dry to obtain enzymatic silk fibroin for future use.

preparation Embodiment 3

[0069] Soak the cocoon and pupal lining in hot water at 70-100°C with a solid-to-liquid weight ratio of 1:10-15 for 1-2 hours, then boil for 0.5-2 hours, filter to remove residue, and prepare the liquid for later use, or concentrate the liquid to obtain silk fibroin cream Save the body for later use.

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Abstract

The invention relates to a health-care preparation, in particular to a health-care preparation which is prepared by using silkworm cocoon as main raw materials and has auxiliary control effects on hypertension, hyperlipaemia and hyperglycemia, and a production method thereof. The main components of the health-care preparation include silkworm cocoon fibroin, black soya bean, Rehmannia glutinosa, medlar, dogwood and rhizoma alismatis. The prepared health-care preparation has the effects of promoting nutrient supply of human bodies, lowering cholesterol concentration and blood sugar level in blood of the human bodies, preventing cardiovascular and cerebrovascular diseases, helping to restore body immunity and the like.

Description

technical field [0001] The invention relates to a health-care preparation, especially a health-care preparation which uses silkworm cocoons as the main raw material and has an auxiliary control effect on hypertension, hyperlipidemia and hyperglycemia and a production method thereof. Background technique [0002] When people are middle-aged and elderly, many symptoms are easy to appear, especially the symptoms of "three highs", namely high blood pressure, high blood fat and high blood sugar. It is a common disease of modern people, mainly because with the improvement of living standards, the intake of high-fat, high-protein, high-sugar, and high-calorie diets makes the incidence of cardiovascular diseases on the rise, which seriously threatens human health. The research on hyperlipidemia, hyperlipidemia and hyperglycemia has become a hotspot in clinical and basic research, while hypertension, hyperlipidemia and hyperglycemia are mainly caused by disorders of lipid metabolism ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L1/29A23L33/00
Inventor 曾光强
Owner 曾光强
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