Application of mussel agglutinin to preparation of cosmetics

A technology of mussel lectin and cosmetics, applied in the application field of mussel lectin in the preparation of cosmetics, to achieve the effects of easy source, avoiding skin aging, and simple and mature preparation process

Inactive Publication Date: 2012-02-29
DALIAN OCEAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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  • Application of mussel agglutinin to preparation of cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Determination of growth-promoting activity of skin cream containing mussel agglutinin (CGL) on fibroblasts:

[0010] 1. Sample Preparation

[0011] N-acetylgalactosamine / galactose (GalNAc / Gal)-specific mussel lectin (CGL) according to Li Wei, Xiong Chuannan and Wang Jianhua et al. in "Journal of Shenyang Agricultural University", 2007, Vol. 38, No. 2 It was prepared by the method described in "Studies on the Anti-HIV Activity of Mussel Lectin" published on pages 207-210 of the issue.

[0012] Skin care cream is formula shown in table 1:

[0013] Table 1

[0014] Element mass percentage Element mass percentage Glyceryl monostearate 8 Propylparaben 0.5 stearic acid 8 Glycerol 10 cetyl alcohol 1 Triethanolamine 1 Propyl paraben 0.1 distilled water 69.9 Simethicone 1 essence 0.5

[0015] (1) Sample preparation of skin cream containing lectin: According to Table 1, t...

Embodiment 2

[0028] Determination of protective activity of mussel lectin (CGL)-containing skin cream against UV damage in fibroblasts:

[0029] 1. Sample Preparation:

[0030] The preparation methods of mussel lectin (CGL) and skin cream are the same as in Example 1.

[0031] (1) Sample preparation of lectin-containing skin cream: sample preparation of lectin-containing skin cream: mix the oil-phase raw materials and oil-soluble emulsifier according to the above table, mix and heat to 80°C under constant stirring, and maintain for 20 minutes to sterilize , add the water phase raw materials and water-soluble emulsifier to distilled water, heat to 80°C under stirring, maintain 20min for sterilization, and then cool down, add mussel agglutinin (CGL) with a mass ratio of 1 / 10,000 to the skin cream Slowly add to the water phase to stir and emulsify, then add the water phase to the oil phase, add the essence when the temperature drops to 45°C, continue to stir and cool, and then the skin crea...

Embodiment 3

[0044] Examples 1 and 2 respectively show that N-acetylgalactosamine / galactose (GalNAc / Gal)-specific mussel agglutinin (CGL) can significantly promote the growth of fibroblasts and protect fibroblasts from ultraviolet damage . For this purpose, N-acetylgalactosamine / galactose (GalNAc / Gal) specific mussel agglutinin (CGL) can be added to Among the basic raw materials of existing cosmetics, it can be made into skin cream, eye cream, barrier cream, hand cream and massage cream, etc., which can be applied to the skin to prevent skin damage caused by ultraviolet rays.

[0045] Prepare hand cream according to the formula proportioning shown in table 4:

[0046] Table 4

[0047]

[0048] According to Table 4, mix and heat the oil phase raw materials and oil-soluble emulsifier to 80°C under constant stirring, maintain for 20 minutes for sterilization, add the water phase raw materials and water-soluble emulsifier into distilled water, and ...

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Abstract

The invention discloses an application of mussel agglutinin to the preparation of cosmetics. The mussel agglutinin is specific mussel agglutinin (CGL) of N-acetyl galactosamine/galactose (GalNAc/Gal), namely the mussel agglutinin is used as a biological active constituent and is added into skin-care cosmetics. The mussel agglutinin has obvious functions of promoting growth of a fibroblast and protecting the fibroblast from ultraviolet radiation damage, so that the ultraviolet radiation damage can be effectively prevented, and skin ageing and the like caused by the ultraviolet radiation damage can be avoided; the mussel agglutinin is from mussel, so that the raw material of the mussel agglutinin can be obtained easily and is safe and reliable; the preparation process is simple and mature; and the mussel agglutinin is low in cost and convenient to apply.

Description

field of invention [0001] The invention relates to a new application of mussel agglutinin, especially the application of mussel agglutinin in preparing cosmetics. Background technique [0002] At present, there are many kinds of cosmetics, such as skin cream, eye cream, barrier cream, hand cream and massage cream. For example, the Chinese invention patent number is ZL02817885.8, and the invention patent named "Silicon dioxide-coated mixed crystal oxide particles, its preparation method and cosmetic materials prepared therefrom" discloses a sunscreen (prevention of skin damage caused by ultraviolet rays) ) functional cosmetics are made by adding silicon dioxide-coated mixed crystal oxide particles with the ability to block ultraviolet rays to the basic raw materials of cosmetics, that is, to prevent ultraviolet damage through physical methods. There is also a sunscreen cosmetic that adds fibroblast growth factor to the cosmetic base material to prevent ultraviolet damage by...

Claims

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Application Information

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IPC IPC(8): A61K8/64A61Q17/04
Inventor 李伟孔亮曲敏佟长青谭成玉金桥
Owner DALIAN OCEAN UNIV
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