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Unitary-package-reaction-type chlorine dioxide tablet and preparation method thereof

A chlorine dioxide tablet, chlorine dioxide tablet technology, applied in the directions of botanical equipment and methods, applications, biocides, etc., can solve the problems of difficult to guarantee stability, low conversion rate, etc., and achieve high product stability, Easy to store and ensure stability

Inactive Publication Date: 2012-03-21
ZHONGBEI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some shortcomings in this type of preparations sold on the market, such as low conversion rate, difficult to guarantee stability, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] 1) Raw material pretreatment

[0042] Dry each raw material at 40-120°C for 2 hours, and cool down in a desiccator; grind the dried raw material and pass it through a 100-120 mesh sieve, and keep the raw material with an intermediate particle size;

[0043] 2) Preparation of plain tablets

[0044] Weigh 9Kg of sodium chlorite, 30Kg of sulfamic acid, 9Kg of sodium bromide, 15Kg of β-cyclodextrin, 0.7Kg of magnesium stearate, and 10Kg of sodium bicarbonate. Chlorine oxide tablets;

[0045] 3) Coating of tablets

[0046] Adopt concentration to be 75% ethanol solution to dissolve polyethylene glycol, be mixed with the polyethylene glycol coating solution that the concentration of sufficient volume is 6%, by means of coating pan, 2) the one element reaction type chlorine dioxide tablet that makes Coating, drying to obtain one-package reactive chlorine dioxide tablet;

[0047] 4) Packaging of tablets

[0048] Utilize the medical polyvinyl chloride film to pack the one-pa...

Embodiment 2

[0050] Sodium chlorite 8Kg, sulfamic acid 30Kg, sodium bromide 11.5Kg, β-cyclodextrin 17Kg, magnesium stearate 1Kg, sodium bicarbonate 12Kg, preparation steps are the same as embodiment 1.

Embodiment 3

[0052] Sodium chlorite 9Kg, sulfamic acid 20Kg, sodium bisulfate 10Kg, sodium bromide 4.5Kg, glucose 4.5Kg, polyvinylpyrrolidone 10Kg, β-cyclodextrin 5Kg, magnesium stearate 0.7Kg, sodium carbonate 10Kg, prepared Step is with embodiment 1.

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PUM

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Abstract

The invention provides a unitary-package-reaction-type chlorine dioxide tablet and a preparation method thereof. The tablet is prepared from the following raw materials: 8-20wt% of raw agent, 25-50wt% of acidulant, 8-20wt% of promoter, 15-25wt% of binder, 0.5-4wt% of lubricant and 10-22wt% of foaming agent. The preparation method comprises the following steps: mixing and pressing the raw materials into white pills; and then coating the white pills by a coating agent to finally obtain the chlorine dioxide tablet. When the chlorine dioxide tablet is in use, chlorine dioxide gas can be generated only by dissolving the tablet in water so as to play roles in sterilization and disinfection. The unitary-package-reaction-type chlorine dioxide tablet obtained by the preparation method has the advantages of high conversion rate, convenience in storage and high product stability.

Description

technical field [0001] The invention belongs to the technical field of chlorine dioxide disinfection, and in particular relates to a reactive chlorine dioxide solid preparation composed of alkali metal or alkaline earth metal chlorite such as sodium chlorite, solid acid and other accelerators. The invention also relates to a preparation method of the solid preparation. Background technique [0002] As a water-soluble strong oxidant, chlorine dioxide has high-efficiency and broad-spectrum bactericidal ability, and can oxidize and decompose bacteria, viruses and other microorganisms, as well as amino acids and other reducing substances in proteins, and can also react with organic matter and various inorganic ions reaction; and, compared with other chlorine-based products, chlorine dioxide will not produce distortion-causing, carcinogenic, mutagenic chloroform and other organic halides during sterilization, and the effect of killing viruses, bacteria, deodorization, bleaching, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/00A01N25/34A01P1/00
Inventor 晋日亚程仕勇李建锐
Owner ZHONGBEI UNIV
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