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Application of plant extract composition to preparation of food or medicine for preventing and treating alcoholic liver injury

A technology of alcoholic liver damage and plant extracts, applied in the fields of natural health food and pharmaceuticals, can solve the problems of liver cell damage, liver damage, and affecting biological activity, etc., and achieve the effect of simple preparation process, wide range of sources, and low cost

Inactive Publication Date: 2012-03-21
YANGZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] (3) Generate free radicals, exacerbate cell lipid peroxidation, and reduce the activity of the free radical scavenging system in liver cells, thereby triggering a series of free radical toxicity;
[0009] (6) Cytokines are produced, leading to liver cell damage and even liver cirrhosis;
[0010] (7) Acetaldehyde can explain protein and affect its biological activity
At present, there is no specific medicine for alcoholic liver damage, and some western medicines that are effective for fatty liver also have certain damage to the liver itself

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Preparation of extract (take the preparation of "lyophilized powder" as an example):

[0032] (1) Crush Hovenia dulcis seeds, green fruits and mulberries, and pass through 20-30 mesh sieves;

[0033] (2) Add 3 to 5 times the weight of water and decoct 3 to 5 times, each time for 1 to 2 hours, remove the dregs, take the medicinal juice and combine the filtrate;

[0034] (3) concentrating the obtained filtrate under reduced pressure at 70-90°C to obtain extract;

[0035] (4) Refrigerate the extract at low temperature for one day and night, dry it in vacuum, crush it, and pass it through a 80-120 mesh sieve to obtain freeze-dried extract powders of three kinds of extracts.

Embodiment 2

[0037] Preparation of health food or medicine (take the preparation of "hangover oral liquid" as an example):

[0038] (1) Mix the 3 kinds of extract freeze-dried powder according to the following weight ratio: 4 parts of Hovenia dulcis fruit extract, 3 parts of mulberry fruit extract, 3 parts of green fruit extract, and then add 0.5% taurine, citric acid 0.02%, vitamin C 0.03%, sucrose 7%, stabilizer 0.15%, etc., then add sterile water to make a liquid;

[0039] (2) The finished oral liquid is processed into the final product through filtration, sterilization, bottling, etc.

[0040]

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PUM

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Abstract

The invention belongs to the technical fields of natural health-care foods and pharmacy, and relates to application of a hovenia dulcis thumb, mulberry fruit and Chinese white olive extract composition to preparation of a medicine for preventing and treating alcoholic liver injury. The plant extract composition consists of the following components in part by weight: 2 to 5 parts of hovenia dulcis thumb extract, 1 to 3 parts of mulberry fruit extract and 2 to 4 parts of Chinese white olive extract. Experimental verification proves that the composition has an auxiliary protection effect on the alcoholic liver injury. The composition can be used for various liver-protecting health-care foods or medicines.

Description

technical field [0001] The invention belongs to the technical field of natural health food and pharmacy, and relates to the liver-protecting efficacy of Hovenia dulcis fruit, mulberry fruit and green fruit extract composition and a preparation method thereof. Background technique [0002] Statistics from the World Health Organization show that there are nearly 200 million long-term drinkers in my country at present, and the number of ordinary drinkers who drink alcohol exceeds 500 million, and 110,000 people die every year due to alcohol poisoning. [0003] From a physiological and biochemical point of view, after drinking, 90%-95% of alcohol is converted into acetaldehyde in the body, and then into acetic acid, and 5%-10% is excreted from the lungs, kidneys, and skin. The liver is the main organ for alcohol metabolism, and a small amount of alcohol is oxidized in the kidneys, muscles, intestines and lungs. Excessive drinking, bear the brunt of the impact and the most serio...

Claims

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Application Information

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IPC IPC(8): A61K36/72A61P1/16A23L1/29A23L33/00
Inventor 崔桂友唐晖慧
Owner YANGZHOU UNIV
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